Calcium in PDB 8ha2: Crystal Structure of Voltage-Gated Sodium Channel Navab N49K/L176G Mutant in Calcium Ion Condition

The structure of Crystal Structure of Voltage-Gated Sodium Channel Navab N49K/L176G Mutant in Calcium Ion Condition, PDB code: 8ha2 was solved by K.Irie, Y.Oda, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.96 / 3.30
Space group	I 4 2 2
Cell size a, b, c (Å), α, β, γ (°)	127.13, 127.13, 200.55, 90, 90, 90
R / Rfree (%)	26.1 / 28.1

The binding sites of Calcium atom in the Crystal Structure of Voltage-Gated Sodium Channel Navab N49K/L176G Mutant in Calcium Ion Condition (pdb code 8ha2). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of Voltage-Gated Sodium Channel Navab N49K/L176G Mutant in Calcium Ion Condition, PDB code: 8ha2:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of Voltage-Gated Sodium Channel Navab N49K/L176G Mutant in Calcium Ion Condition


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Voltage-Gated Sodium Channel Navab N49K/L176G Mutant in Calcium Ion Condition within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1312 b:103.0 occ:0.25 O A:HOH1411 2.9 97.4 0.2 CA A:CA1313 4.6 113.9 1.0 O A:GLY1176 5.0 54.2 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of Voltage-Gated Sodium Channel Navab N49K/L176G Mutant in Calcium Ion Condition


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Voltage-Gated Sodium Channel Navab N49K/L176G Mutant in Calcium Ion Condition within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1313 b:113.9 occ:1.00 O6' A:LMT1301 3.8 95.1 1.0 CA A:CA1312 4.6 103.0 0.2

K.Irie, Y.Oda, T.Sumikama, A.Oshima, Y.Fujiyoshi. The Structural Basis of Divalent Cation Block in A Tetrameric Prokaryotic Sodium Channel. Nat Commun V. 14 4236 2023.
ISSN: ESSN 2041-1723
PubMed: 37454189
DOI: 10.1038/S41467-023-39987-0