Calcium in PDB 8hpy: Crystal Structure of Human LGI1-ADAM22 Complex

The structure of Crystal Structure of Human LGI1-ADAM22 Complex, PDB code: 8hpy was solved by H.Liu, F.Xu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.08 / 5.87
Space group	I 2 3
Cell size a, b, c (Å), α, β, γ (°)	280.342, 280.342, 280.342, 90, 90, 90
R / Rfree (%)	30.3 / 34.3

The binding sites of Calcium atom in the Crystal Structure of Human LGI1-ADAM22 Complex (pdb code 8hpy). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 8 binding sites of Calcium where determined in the Crystal Structure of Human LGI1-ADAM22 Complex, PDB code: 8hpy:
Jump to Calcium binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Calcium binding site 1 out of 8 in the Crystal Structure of Human LGI1-ADAM22 Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Human LGI1-ADAM22 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca804 b:472.1 occ:1.00 OD1 A:ASN436 2.2 476.1 1.0 OD2 A:ASP325 2.2 448.2 1.0 O A:CYS433 2.6 447.7 1.0 CG A:ASN436 2.8 478.8 1.0 CB A:ASN436 2.9 474.8 1.0 OE1 A:GLU242 2.9 475.8 1.0 CG A:ASP325 3.0 443.1 1.0 OD1 A:ASP325 3.0 444.5 1.0 O A:ASN436 3.5 475.6 1.0 CD A:GLU242 3.6 482.4 1.0 N A:ASN436 3.7 455.6 1.0 CA A:ASN436 3.7 470.0 1.0 C A:CYS433 3.8 446.5 1.0 CG A:GLU242 3.8 469.6 1.0 O A:TYR240 4.0 438.2 1.0 C A:ASN436 4.1 476.2 1.0 ND2 A:ASN436 4.1 482.0 1.0 CB A:GLU242 4.2 458.2 1.0 CA A:LEU434 4.3 443.5 1.0 CB A:ASP325 4.4 434.2 1.0 N A:LEU434 4.5 446.8 1.0 C A:LEU434 4.5 444.7 1.0 OE2 A:GLU242 4.5 500.6 1.0 N A:GLU242 4.6 444.8 1.0 CB A:CYS433 4.7 438.1 1.0 N A:PHE435 4.7 439.4 1.0 CA A:CYS433 4.8 449.2 1.0 C A:PHE435 4.9 445.6 1.0 CA A:GLU242 5.0 451.6 1.0

Calcium binding site 2 out of 8 in the Crystal Structure of Human LGI1-ADAM22 Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Human LGI1-ADAM22 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca805 b:461.4 occ:1.00 O A:PHE451 2.1 471.5 1.0 OD2 A:ASP459 2.1 474.3 1.0 O A:GLU446 2.2 467.6 1.0 OD1 A:ASN449 2.3 468.9 1.0 OE2 A:GLU456 2.8 474.7 1.0 OE2 A:GLU453 2.9 451.8 1.0 OE1 A:GLU456 3.0 481.3 1.0 CG A:ASN449 3.2 467.7 1.0 CG A:ASP459 3.3 474.9 1.0 CD A:GLU456 3.3 479.8 1.0 C A:PHE451 3.3 472.3 1.0 C A:GLU446 3.4 471.3 1.0 ND2 A:ASN449 3.8 461.8 1.0 OD1 A:ASP459 3.8 472.5 1.0 N A:PHE451 4.0 477.2 1.0 CA A:PHE451 4.1 475.0 1.0 CD A:GLU453 4.2 451.8 1.0 N A:GLU446 4.2 466.2 1.0 CA A:CYS447 4.3 478.6 1.0 N A:GLU453 4.3 471.3 1.0 N A:CYS447 4.3 476.9 1.0 N A:ILE452 4.3 466.3 1.0 CB A:ASN449 4.4 469.9 1.0 CA A:GLU446 4.4 470.5 1.0 CB A:ASP459 4.4 477.3 1.0 CB A:PHE451 4.4 478.1 1.0 N A:ASN449 4.5 473.9 1.0 CB A:GLU453 4.6 471.2 1.0 CA A:ILE452 4.6 464.0 1.0 N A:GLY448 4.7 475.2 1.0 CG A:GLU456 4.8 479.8 1.0 C A:ILE452 4.8 465.0 1.0 N A:GLY450 4.8 476.9 1.0 C A:CYS447 4.8 479.7 1.0 CG A:GLU453 4.9 465.3 1.0 CA A:ASN449 4.9 473.0 1.0

Calcium binding site 3 out of 8 in the Crystal Structure of Human LGI1-ADAM22 Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Crystal Structure of Human LGI1-ADAM22 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca806 b:465.0 occ:1.00 OE1 A:GLU514 2.2 460.8 1.0 OD1 A:ASN526 2.2 469.4 1.0 OD1 A:ASP511 2.4 485.5 1.0 OE2 A:GLU514 2.6 475.2 1.0 CD A:GLU514 2.7 473.5 1.0 OD2 A:ASP511 2.9 484.0 1.0 CG A:ASP511 3.0 486.2 1.0 O A:ILE512 3.0 499.3 1.0 CG A:ASN526 3.0 469.6 1.0 O A:ILE527 3.1 478.9 1.0 ND2 A:ASN526 3.5 471.3 1.0 N A:ILE527 3.7 466.6 1.0 C A:ILE527 4.0 472.0 1.0 C A:ILE512 4.1 498.9 1.0 CB A:ASN526 4.2 473.4 1.0 CG A:GLU514 4.2 488.3 1.0 CA A:ASN526 4.2 471.6 1.0 C A:ASN526 4.4 469.0 1.0 N A:ILE512 4.5 492.5 1.0 CB A:ASP511 4.5 485.4 1.0 CA A:ILE527 4.5 464.5 1.0 N A:HIS528 4.9 473.3 1.0 CA A:ILE512 4.9 496.3 1.0

Calcium binding site 4 out of 8 in the Crystal Structure of Human LGI1-ADAM22 Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Crystal Structure of Human LGI1-ADAM22 Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca604 b:368.9 occ:1.00 O D:VAL382 2.4 344.4 1.0 OE1 D:GLU383 2.5 353.7 1.0 OD2 D:ASP334 2.5 338.8 1.0 OD1 D:ASP381 2.7 319.6 1.0 OE2 D:GLU336 3.0 358.7 1.0 CG D:ASP381 3.4 320.8 1.0 OD2 D:ASP381 3.5 320.2 1.0 C D:VAL382 3.5 336.5 1.0 CG D:ASP334 3.6 345.3 1.0 CD D:GLU383 3.7 335.4 1.0 NZ D:LYS436 3.9 304.5 1.0 CD D:GLU336 4.0 345.5 1.0 OD1 D:ASP334 4.0 346.6 1.0 N D:VAL382 4.2 326.9 1.0 CA D:GLU383 4.3 331.1 1.0 CE D:LYS436 4.3 308.1 1.0 N D:GLU383 4.3 332.1 1.0 CB D:GLU383 4.3 332.4 1.0 OE1 D:GLU336 4.5 341.0 1.0 OE2 D:GLU383 4.5 327.2 1.0 CA D:VAL382 4.6 332.7 1.0 CG D:GLU383 4.7 330.2 1.0 O D:VAL435 4.7 327.7 1.0 CD D:LYS436 4.7 319.6 1.0 CB D:ASP334 4.8 354.4 1.0 CB D:ASP381 4.8 323.6 1.0 CG1 D:VAL382 5.0 350.4 1.0

Calcium binding site 5 out of 8 in the Crystal Structure of Human LGI1-ADAM22 Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Crystal Structure of Human LGI1-ADAM22 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca804 b:404.1 occ:1.00 OE1 B:GLU242 2.6 401.4 1.0 CB B:ASN436 2.7 425.4 1.0 O B:CYS433 2.8 370.7 1.0 OD1 B:ASP325 2.9 392.3 1.0 OD1 B:ASN436 3.2 438.4 1.0 OD2 B:ASP325 3.2 394.9 1.0 CG B:ASN436 3.4 427.5 1.0 CG B:ASP325 3.5 393.1 1.0 CD B:GLU242 3.8 400.3 1.0 C B:CYS433 3.9 368.3 1.0 CB B:CYS433 4.0 366.1 1.0 CA B:ASN436 4.0 425.8 1.0 N B:ASN436 4.2 417.3 1.0 OE2 B:GLU242 4.4 406.7 1.0 CA B:CYS433 4.4 372.6 1.0 ND2 B:ASN436 4.7 427.3 1.0 O B:ASN436 4.7 420.5 1.0 C B:ASN436 4.9 428.2 1.0 SG B:CYS433 4.9 364.1 1.0 CB B:ASP325 5.0 392.9 1.0 CG B:GLU242 5.0 398.6 1.0

Calcium binding site 6 out of 8 in the Crystal Structure of Human LGI1-ADAM22 Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 6 of Crystal Structure of Human LGI1-ADAM22 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca805 b:525.0 occ:1.00 OD2 B:ASP459 2.2 521.3 1.0 O B:PHE451 2.3 511.7 1.0 OE1 B:GLU453 2.3 501.2 1.0 O B:GLU446 2.4 519.8 1.0 OD1 B:ASN449 2.7 510.9 1.0 OE2 B:GLU456 2.7 505.9 1.0 OE1 B:GLU456 2.8 518.3 1.0 CG B:GLU453 3.0 496.8 1.0 CD B:GLU453 3.0 496.3 1.0 CD B:GLU456 3.1 506.2 1.0 CG B:ASP459 3.4 517.5 1.0 C B:PHE451 3.5 505.2 1.0 C B:GLU446 3.6 520.0 1.0 CG B:ASN449 3.7 509.0 1.0 CB B:ASP459 4.1 516.4 1.0 CA B:CYS447 4.2 523.1 1.0 N B:PHE451 4.2 506.9 1.0 ND2 B:ASN449 4.2 506.3 1.0 OE2 B:GLU453 4.3 488.8 1.0 N B:GLU453 4.3 490.6 1.0 N B:CYS447 4.3 523.4 1.0 CA B:PHE451 4.4 503.8 1.0 OD1 B:ASP459 4.4 513.5 1.0 N B:GLU446 4.4 517.7 1.0 N B:ILE452 4.4 497.5 1.0 CB B:GLU453 4.5 490.6 1.0 CA B:ILE452 4.6 492.8 1.0 CA B:GLU446 4.6 518.4 1.0 CG B:GLU456 4.6 494.7 1.0 N B:ASN449 4.7 514.6 1.0 N B:GLY448 4.7 522.2 1.0 C B:CYS447 4.8 521.4 1.0 CB B:PHE451 4.8 498.6 1.0 C B:ILE452 4.9 486.7 1.0 CB B:ASN449 4.9 509.8 1.0 N B:GLY450 4.9 509.0 1.0

Calcium binding site 7 out of 8 in the Crystal Structure of Human LGI1-ADAM22 Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 7 of Crystal Structure of Human LGI1-ADAM22 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca806 b:419.2 occ:1.00 OD1 B:ASN526 2.2 405.6 1.0 OE2 B:GLU514 2.3 413.0 1.0 OE1 B:GLU514 2.4 404.3 1.0 OD1 B:ASP511 2.5 393.9 1.0 O B:ILE512 2.6 396.3 1.0 O B:ILE527 2.6 395.1 1.0 CD B:GLU514 2.6 407.4 1.0 CG B:ASN526 3.2 406.7 1.0 N B:ILE527 3.2 402.1 1.0 CG B:ASP511 3.2 387.3 1.0 OD2 B:ASP511 3.3 385.4 1.0 C B:ILE527 3.5 391.8 1.0 C B:ILE512 3.8 394.4 1.0 ND2 B:ASN526 3.9 400.9 1.0 CA B:ILE527 4.0 394.6 1.0 CA B:ASN526 4.1 413.3 1.0 CG B:GLU514 4.1 411.0 1.0 C B:ASN526 4.1 406.1 1.0 CB B:ASN526 4.2 412.8 1.0 N B:ILE512 4.2 394.9 1.0 N B:HIS528 4.6 387.4 1.0 CA B:ILE512 4.6 392.8 1.0 CB B:ASP511 4.7 379.9 1.0 N B:ARG513 4.8 391.3 1.0 CB B:ILE527 4.8 397.3 1.0 N B:GLU514 4.8 411.6 1.0 CA B:ARG513 4.9 398.9 1.0 CB B:GLU514 4.9 410.5 1.0 CA B:HIS528 5.0 388.2 1.0

Calcium binding site 8 out of 8 in the Crystal Structure of Human LGI1-ADAM22 Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 8 of Crystal Structure of Human LGI1-ADAM22 Complex within 5.0Å range: probe atom residue distance (Å) B Occ E:Ca604 b:363.4 occ:1.00 O E:VAL382 2.1 336.9 1.0 OE1 E:GLU383 2.4 348.2 1.0 OE2 E:GLU336 2.9 352.0 1.0 OD2 E:ASP334 3.0 326.4 1.0 C E:VAL382 3.3 315.9 1.0 CD E:GLU383 3.4 340.9 1.0 OD1 E:ASP381 3.5 340.2 1.0 CD E:GLU336 3.5 339.4 1.0 OD2 E:ASP381 3.7 345.8 1.0 CA E:GLU383 3.8 315.8 1.0 OE1 E:GLU336 3.9 334.7 1.0 CG E:ASP381 4.0 345.6 1.0 N E:GLU383 4.0 308.1 1.0 CB E:GLU383 4.1 322.8 1.0 NZ E:LYS436 4.1 352.5 1.0 OE2 E:GLU383 4.2 340.3 1.0 CG E:ASP334 4.2 328.4 1.0 N E:VAL382 4.3 332.2 1.0 CG E:GLU383 4.4 333.1 1.0 CA E:VAL382 4.5 322.6 1.0 CB E:GLU336 4.5 326.4 1.0 CG E:GLU336 4.5 329.4 1.0 CE E:LYS436 4.6 357.4 1.0 OD1 E:ASP334 4.7 316.5 1.0 O E:VAL435 4.8 337.2 1.0 CG1 E:VAL382 4.8 322.7 1.0 CD E:LYS436 4.9 345.8 1.0

H.Liu, F.Xu. Crystal Structure of Human LGI1-ADAM22 Complex To Be Published.