Calcium in PDB 8tkp: Structure of the C. Elegans Tmc-2 Complex

The binding sites of Calcium atom in the Structure of the C. Elegans Tmc-2 Complex (pdb code 8tkp). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Structure of the C. Elegans Tmc-2 Complex, PDB code: 8tkp:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Structure of the C. Elegans Tmc-2 Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of the C. Elegans Tmc-2 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca301 b:66.1 occ:0.98 OE1 B:GLU182 2.3 63.2 1.0 OD1 B:ASP175 2.3 78.9 0.8 OD2 B:ASP175 2.4 78.9 0.8 O B:SER177 2.4 67.7 1.0 OE2 B:GLU182 2.4 63.2 0.8 CG B:ASP175 2.6 78.9 0.9 CD B:GLU182 2.7 63.2 0.9 OD2 B:ASP173 3.5 90.0 0.6 C B:SER177 3.5 67.7 1.0 ND2 B:ASN179 3.7 58.8 0.8 CB B:ASP173 3.7 90.0 0.8 OD2 B:ASP171 3.7 84.9 0.9 N B:ASN179 3.7 58.8 1.0 CG B:ASN179 3.8 58.8 0.9 CG B:ASP171 3.9 84.9 0.9 OD1 B:ASP171 4.0 84.9 0.9 CG B:ASP173 4.0 90.0 0.6 OD1 B:ASN179 4.1 58.8 0.9 CG B:GLU182 4.1 63.2 0.9 CA B:ILE178 4.2 56.2 1.0 CB B:ASP175 4.2 78.9 0.9 N B:ILE178 4.3 56.2 1.0 C B:ILE178 4.4 56.2 1.0 CB B:ASN179 4.4 58.8 1.0 N B:ASP173 4.4 90.0 1.0 OG B:SER177 4.5 67.7 1.0 N B:SER177 4.6 67.7 1.0 CA B:ASP171 4.6 84.9 1.0 CA B:ASP173 4.6 90.0 0.9 CA B:SER177 4.6 67.7 1.0 CB B:ASP171 4.7 84.9 1.0 N B:ASP175 4.7 78.9 1.0 CA B:ASN179 4.7 58.8 1.0 CA B:ASP175 4.9 78.9 1.0

Calcium binding site 2 out of 4 in the Structure of the C. Elegans Tmc-2 Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of the C. Elegans Tmc-2 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca302 b:80.4 occ:0.78 OD2 B:ASP141 2.3 83.4 0.8 OD1 B:ASP134 2.3 81.1 0.8 OD2 B:ASP132 2.3 80.7 0.7 O B:LEU136 2.3 72.1 0.8 OD1 B:ASP132 2.3 80.7 0.8 CG B:ASP132 2.6 80.7 0.7 CG B:ASP134 3.0 81.1 0.9 OD2 B:ASP134 3.0 81.1 0.9 OD1 B:ASP130 3.0 67.7 1.0 N B:GLY138 3.4 78.5 1.0 CG B:ASP141 3.4 83.4 0.8 C B:LEU136 3.5 72.1 1.0 CD1 B:LEU136 4.0 72.1 1.0 OD1 B:ASP141 4.1 83.4 0.8 CA B:GLY138 4.1 78.5 1.0 CB B:ASP132 4.1 80.7 0.9 CA B:LEU137 4.2 61.7 1.0 CG B:ASP130 4.2 67.7 0.9 C B:LEU137 4.2 61.7 1.0 N B:LEU137 4.3 61.7 1.0 CB B:ASP134 4.4 81.1 1.0 CB B:ASP141 4.6 83.4 1.0 N B:LEU136 4.6 72.1 1.0 CA B:LEU136 4.6 72.1 1.0 N B:ASP134 4.7 81.1 1.0 N B:ASP132 4.8 80.7 1.0 OD2 B:ASP130 4.8 67.7 0.7 OD1 B:ASP140 4.9 81.5 0.9 CA B:ASP132 5.0 80.7 1.0 CA B:ASP134 5.0 81.1 1.0

Calcium binding site 3 out of 4 in the Structure of the C. Elegans Tmc-2 Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Structure of the C. Elegans Tmc-2 Complex within 5.0Å range: probe atom residue distance (Å) B Occ E:Ca301 b:72.9 occ:1.00 OE1 E:GLU182 2.3 65.9 0.8 OD1 E:ASP175 2.3 81.5 1.0 O E:SER177 2.3 71.2 1.0 OE2 E:GLU182 2.4 65.9 0.8 OD2 E:ASP175 2.4 81.5 0.9 CD E:GLU182 2.6 65.9 0.9 CG E:ASP175 2.7 81.5 0.9 C E:SER177 3.5 71.2 1.0 ND2 E:ASN179 3.8 61.3 0.8 OD1 E:ASP171 3.8 92.5 1.0 N E:ASN179 3.9 61.3 1.0 OD2 E:ASP173 3.9 97.8 0.7 CG E:ASP173 3.9 97.8 0.7 CB E:ASP173 3.9 97.8 0.9 CA E:ILE178 4.0 57.7 1.0 CG E:ASN179 4.1 61.3 0.9 CG E:GLU182 4.2 65.9 0.9 N E:ILE178 4.2 57.7 1.0 CB E:ASP175 4.2 81.5 1.0 O E:ALA170 4.4 92.1 1.0 C E:ILE178 4.4 57.7 1.0 N E:ASP173 4.5 97.8 0.9 OD1 E:ASN179 4.5 61.3 0.7 OD1 E:ASP173 4.5 97.8 0.6 N E:SER177 4.6 71.2 1.0 CA E:SER177 4.6 71.2 1.0 OG E:SER177 4.6 71.2 0.9 N E:ASP175 4.7 81.5 1.0 CB E:ASN179 4.7 61.3 1.0 CA E:ASP173 4.7 97.8 0.9 CA E:ASP171 4.8 92.5 1.0 CA E:ASN179 4.9 61.3 1.0 CA E:ASP175 5.0 81.5 1.0 N E:LEU172 5.0 95.3 1.0 CB E:GLU182 5.0 65.9 1.0

Calcium binding site 4 out of 4 in the Structure of the C. Elegans Tmc-2 Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Structure of the C. Elegans Tmc-2 Complex within 5.0Å range: probe atom residue distance (Å) B Occ E:Ca302 b:83.4 occ:0.66 OD2 E:ASP132 2.3 78.2 0.8 O E:LEU136 2.3 68.9 0.8 OD2 E:ASP141 2.3 80.6 0.8 OD1 E:ASP134 2.3 79.1 0.7 OD1 E:ASP132 2.4 78.2 0.8 CG E:ASP132 2.7 78.2 0.8 OD2 E:ASP134 2.9 79.1 0.8 CG E:ASP134 3.0 79.1 0.9 OD1 E:ASP130 3.3 62.3 0.9 CG E:ASP141 3.4 80.6 0.8 C E:LEU136 3.5 68.9 1.0 N E:GLY138 3.6 74.5 1.0 OD1 E:ASP141 4.0 80.6 0.7 CB E:ASP132 4.2 78.2 0.9 CA E:GLY138 4.3 74.5 1.0 CA E:LEU136 4.3 68.9 1.0 N E:LEU137 4.4 61.1 1.0 CB E:ASP134 4.4 79.1 1.0 CB E:LEU136 4.4 68.9 1.0 N E:LEU136 4.4 68.9 1.0 CA E:LEU137 4.5 61.1 1.0 C E:LEU137 4.5 61.1 1.0 CG E:ASP130 4.5 62.3 0.9 CB E:ASP141 4.6 80.6 1.0 N E:ASP134 4.7 79.1 1.0 OD1 E:ASP140 4.7 83.2 0.8 N E:ASP132 4.8 78.2 1.0 CA E:ASP132 5.0 78.2 1.0

S.Clark, H.Jeong, R.Posert, A.Goehring, E.Gouaux. The Structure of the Caenorhabditis Elegans Tmc-2 Complex Suggests Roles of Lipid-Mediated Subunit Contacts in Mechanosensory Transduction. Proc.Natl.Acad.Sci.Usa V. 121 96121 2024.
ISSN: ESSN 1091-6490
PubMed: 38354260
DOI: 10.1073/PNAS.2314096121