Calcium in PDB 8vh8: Crystal Structure of Heparosan Synthase 2 From Pasteurella Multocida at 2.85 A

The structure of Crystal Structure of Heparosan Synthase 2 From Pasteurella Multocida at 2.85 A, PDB code: 8vh8 was solved by L.C.Pedersen, J.Liu, E.Stancanelli, J.M.Krahn, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.76 / 2.85
Space group	P 43
Cell size a, b, c (Å), α, β, γ (°)	118.57, 118.57, 262.356, 90, 90, 90
R / Rfree (%)	19.8 / 22.3

The structure of Crystal Structure of Heparosan Synthase 2 From Pasteurella Multocida at 2.85 A also contains other interesting chemical elements:

Sodium	(Na)	4 atoms
Manganese	(Mn)	8 atoms
Chlorine	(Cl)	18 atoms

The binding sites of Calcium atom in the Crystal Structure of Heparosan Synthase 2 From Pasteurella Multocida at 2.85 A (pdb code 8vh8). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Crystal Structure of Heparosan Synthase 2 From Pasteurella Multocida at 2.85 A, PDB code: 8vh8:

Calcium binding site 1 out of 1 in the Crystal Structure of Heparosan Synthase 2 From Pasteurella Multocida at 2.85 A


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Heparosan Synthase 2 From Pasteurella Multocida at 2.85 A within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca708 b:85.8 occ:1.00 OE2 B:GLU226 3.7 75.1 1.0 HD22 B:LEU118 3.7 92.1 1.0 OE1 B:GLU226 3.7 70.3 1.0 OE2 B:GLU223 4.1 67.3 1.0 CD B:GLU226 4.1 72.5 1.0 HG21 B:THR153 4.6 73.2 1.0 CD2 B:LEU118 4.6 76.7 1.0 HD13 B:LEU118 4.7 102.5 1.0 HD21 B:LEU118 4.8 92.1 1.0 HB B:THR153 4.9 73.0 1.0 HG2 B:GLU223 5.0 76.9 1.0

E.Stancanelli, J.A.Krahn, E.Viverette, R.Dutcher, V.Pagadala, M.J.Borgnia, J.Liu, L.C.Pedersen. Structural and Functional Analysis of Heparosan Synthase 2 From Pasteurella Multocida to Improve the Synthesis of Heparin Acs Catalysis V. 14 6577 2024.
ISSN: ESSN 2155-5435
DOI: 10.1021/ACSCATAL.4C00677