Calcium in PDB 8x4c: Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp)
Calcium Binding Sites:
The binding sites of Calcium atom in the Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp)
(pdb code 8x4c). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the
Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp), PDB code: 8x4c:
Jump to Calcium binding site number:
1;
2;
3;
4;
Calcium binding site 1 out
of 4 in 8x4c
Go back to
Calcium Binding Sites List in 8x4c
Calcium binding site 1 out
of 4 in the Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp)
 Mono view
 Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca5102
b:39.2
occ:1.00
|
OE2
|
A:GLU3967
|
2.7
|
41.4
|
1.0
|
O
|
A:THR5001
|
2.9
|
43.4
|
1.0
|
OE1
|
A:GLU3893
|
3.4
|
44.1
|
1.0
|
CD
|
A:GLU3967
|
3.4
|
41.4
|
1.0
|
OE1
|
A:GLU3967
|
3.5
|
41.4
|
1.0
|
O
|
A:GLU3893
|
3.6
|
44.1
|
1.0
|
OE1
|
A:GLN3970
|
3.7
|
40.5
|
1.0
|
C
|
A:THR5001
|
3.9
|
43.4
|
1.0
|
OG1
|
A:THR5001
|
4.0
|
43.4
|
1.0
|
CD
|
A:GLU3893
|
4.3
|
44.1
|
1.0
|
O
|
A:HIS5003
|
4.4
|
38.2
|
1.0
|
CA
|
A:THR5001
|
4.6
|
43.4
|
1.0
|
C
|
A:GLU3893
|
4.6
|
44.1
|
1.0
|
OE2
|
A:GLU3893
|
4.7
|
44.1
|
1.0
|
CD
|
A:GLN3970
|
4.8
|
40.5
|
1.0
|
N
|
A:GLU5002
|
4.8
|
42.9
|
1.0
|
CG
|
A:GLU3967
|
4.9
|
41.4
|
1.0
|
CB
|
A:THR5001
|
5.0
|
43.4
|
1.0
|
|
Calcium binding site 2 out
of 4 in 8x4c
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Calcium Binding Sites List in 8x4c
Calcium binding site 2 out
of 4 in the Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp)
 Mono view
 Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca5102
b:39.2
occ:1.00
|
OE2
|
B:GLU3967
|
2.7
|
41.4
|
1.0
|
O
|
B:THR5001
|
2.9
|
43.4
|
1.0
|
OE1
|
B:GLU3893
|
3.4
|
44.1
|
1.0
|
CD
|
B:GLU3967
|
3.4
|
41.4
|
1.0
|
OE1
|
B:GLU3967
|
3.5
|
41.4
|
1.0
|
O
|
B:GLU3893
|
3.6
|
44.1
|
1.0
|
OE1
|
B:GLN3970
|
3.7
|
40.5
|
1.0
|
C
|
B:THR5001
|
3.9
|
43.4
|
1.0
|
OG1
|
B:THR5001
|
4.0
|
43.4
|
1.0
|
CD
|
B:GLU3893
|
4.3
|
44.1
|
1.0
|
O
|
B:HIS5003
|
4.4
|
38.2
|
1.0
|
CA
|
B:THR5001
|
4.6
|
43.4
|
1.0
|
C
|
B:GLU3893
|
4.6
|
44.1
|
1.0
|
OE2
|
B:GLU3893
|
4.7
|
44.1
|
1.0
|
CD
|
B:GLN3970
|
4.8
|
40.5
|
1.0
|
N
|
B:GLU5002
|
4.8
|
42.9
|
1.0
|
CG
|
B:GLU3967
|
4.9
|
41.4
|
1.0
|
CB
|
B:THR5001
|
5.0
|
43.4
|
1.0
|
|
Calcium binding site 3 out
of 4 in 8x4c
Go back to
Calcium Binding Sites List in 8x4c
Calcium binding site 3 out
of 4 in the Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp)
 Mono view
 Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca5102
b:39.2
occ:1.00
|
OE2
|
C:GLU3967
|
2.7
|
41.4
|
1.0
|
O
|
C:THR5001
|
2.9
|
43.4
|
1.0
|
OE1
|
C:GLU3893
|
3.4
|
44.1
|
1.0
|
CD
|
C:GLU3967
|
3.4
|
41.4
|
1.0
|
OE1
|
C:GLU3967
|
3.5
|
41.4
|
1.0
|
O
|
C:GLU3893
|
3.6
|
44.1
|
1.0
|
OE1
|
C:GLN3970
|
3.7
|
40.5
|
1.0
|
C
|
C:THR5001
|
3.9
|
43.4
|
1.0
|
OG1
|
C:THR5001
|
4.0
|
43.4
|
1.0
|
CD
|
C:GLU3893
|
4.3
|
44.1
|
1.0
|
O
|
C:HIS5003
|
4.4
|
38.2
|
1.0
|
CA
|
C:THR5001
|
4.6
|
43.4
|
1.0
|
C
|
C:GLU3893
|
4.6
|
44.1
|
1.0
|
OE2
|
C:GLU3893
|
4.7
|
44.1
|
1.0
|
CD
|
C:GLN3970
|
4.8
|
40.5
|
1.0
|
N
|
C:GLU5002
|
4.8
|
42.9
|
1.0
|
CG
|
C:GLU3967
|
4.9
|
41.4
|
1.0
|
CB
|
C:THR5001
|
5.0
|
43.4
|
1.0
|
|
Calcium binding site 4 out
of 4 in 8x4c
Go back to
Calcium Binding Sites List in 8x4c
Calcium binding site 4 out
of 4 in the Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp)
 Mono view
 Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca5102
b:39.2
occ:1.00
|
OE2
|
D:GLU3967
|
2.7
|
41.4
|
1.0
|
O
|
D:THR5001
|
2.9
|
43.4
|
1.0
|
OE1
|
D:GLU3893
|
3.4
|
44.1
|
1.0
|
CD
|
D:GLU3967
|
3.4
|
41.4
|
1.0
|
OE1
|
D:GLU3967
|
3.5
|
41.4
|
1.0
|
O
|
D:GLU3893
|
3.6
|
44.1
|
1.0
|
OE1
|
D:GLN3970
|
3.7
|
40.5
|
1.0
|
C
|
D:THR5001
|
3.9
|
43.4
|
1.0
|
OG1
|
D:THR5001
|
4.0
|
43.4
|
1.0
|
CD
|
D:GLU3893
|
4.3
|
44.1
|
1.0
|
O
|
D:HIS5003
|
4.4
|
38.2
|
1.0
|
CA
|
D:THR5001
|
4.6
|
43.4
|
1.0
|
C
|
D:GLU3893
|
4.6
|
44.1
|
1.0
|
OE2
|
D:GLU3893
|
4.7
|
44.1
|
1.0
|
CD
|
D:GLN3970
|
4.8
|
40.5
|
1.0
|
N
|
D:GLU5002
|
4.8
|
42.9
|
1.0
|
CG
|
D:GLU3967
|
4.9
|
41.4
|
1.0
|
CB
|
D:THR5001
|
5.0
|
43.4
|
1.0
|
|
Reference:
W.Risheng,
Q.Chen,
Z.Lei,
L.Chuang,
Y.Chang-Cheng,
H.Hu.
Structural Insights Into Transmembrane Helix TM0 Facilitated RYR1 Channel Gating By CA2+/Atp To Be Published.
Page generated: Thu Jul 10 08:18:05 2025
|