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Calcium in PDB 8x4c: Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp)

Calcium Binding Sites:

The binding sites of Calcium atom in the Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp) (pdb code 8x4c). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp), PDB code: 8x4c:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in 8x4c

Go back to Calcium Binding Sites List in 8x4c
Calcium binding site 1 out of 4 in the Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca5102

b:39.2
occ:1.00
OE2 A:GLU3967 2.7 41.4 1.0
O A:THR5001 2.9 43.4 1.0
OE1 A:GLU3893 3.4 44.1 1.0
CD A:GLU3967 3.4 41.4 1.0
OE1 A:GLU3967 3.5 41.4 1.0
O A:GLU3893 3.6 44.1 1.0
OE1 A:GLN3970 3.7 40.5 1.0
C A:THR5001 3.9 43.4 1.0
OG1 A:THR5001 4.0 43.4 1.0
CD A:GLU3893 4.3 44.1 1.0
O A:HIS5003 4.4 38.2 1.0
CA A:THR5001 4.6 43.4 1.0
C A:GLU3893 4.6 44.1 1.0
OE2 A:GLU3893 4.7 44.1 1.0
CD A:GLN3970 4.8 40.5 1.0
N A:GLU5002 4.8 42.9 1.0
CG A:GLU3967 4.9 41.4 1.0
CB A:THR5001 5.0 43.4 1.0

Calcium binding site 2 out of 4 in 8x4c

Go back to Calcium Binding Sites List in 8x4c
Calcium binding site 2 out of 4 in the Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp) within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca5102

b:39.2
occ:1.00
OE2 B:GLU3967 2.7 41.4 1.0
O B:THR5001 2.9 43.4 1.0
OE1 B:GLU3893 3.4 44.1 1.0
CD B:GLU3967 3.4 41.4 1.0
OE1 B:GLU3967 3.5 41.4 1.0
O B:GLU3893 3.6 44.1 1.0
OE1 B:GLN3970 3.7 40.5 1.0
C B:THR5001 3.9 43.4 1.0
OG1 B:THR5001 4.0 43.4 1.0
CD B:GLU3893 4.3 44.1 1.0
O B:HIS5003 4.4 38.2 1.0
CA B:THR5001 4.6 43.4 1.0
C B:GLU3893 4.6 44.1 1.0
OE2 B:GLU3893 4.7 44.1 1.0
CD B:GLN3970 4.8 40.5 1.0
N B:GLU5002 4.8 42.9 1.0
CG B:GLU3967 4.9 41.4 1.0
CB B:THR5001 5.0 43.4 1.0

Calcium binding site 3 out of 4 in 8x4c

Go back to Calcium Binding Sites List in 8x4c
Calcium binding site 3 out of 4 in the Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp) within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Ca5102

b:39.2
occ:1.00
OE2 C:GLU3967 2.7 41.4 1.0
O C:THR5001 2.9 43.4 1.0
OE1 C:GLU3893 3.4 44.1 1.0
CD C:GLU3967 3.4 41.4 1.0
OE1 C:GLU3967 3.5 41.4 1.0
O C:GLU3893 3.6 44.1 1.0
OE1 C:GLN3970 3.7 40.5 1.0
C C:THR5001 3.9 43.4 1.0
OG1 C:THR5001 4.0 43.4 1.0
CD C:GLU3893 4.3 44.1 1.0
O C:HIS5003 4.4 38.2 1.0
CA C:THR5001 4.6 43.4 1.0
C C:GLU3893 4.6 44.1 1.0
OE2 C:GLU3893 4.7 44.1 1.0
CD C:GLN3970 4.8 40.5 1.0
N C:GLU5002 4.8 42.9 1.0
CG C:GLU3967 4.9 41.4 1.0
CB C:THR5001 5.0 43.4 1.0

Calcium binding site 4 out of 4 in 8x4c

Go back to Calcium Binding Sites List in 8x4c
Calcium binding site 4 out of 4 in the Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Cryo-Em Structure of Ryanodine Receptor 1 (20 Um CA2+, 2 Mm Atp) within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Ca5102

b:39.2
occ:1.00
OE2 D:GLU3967 2.7 41.4 1.0
O D:THR5001 2.9 43.4 1.0
OE1 D:GLU3893 3.4 44.1 1.0
CD D:GLU3967 3.4 41.4 1.0
OE1 D:GLU3967 3.5 41.4 1.0
O D:GLU3893 3.6 44.1 1.0
OE1 D:GLN3970 3.7 40.5 1.0
C D:THR5001 3.9 43.4 1.0
OG1 D:THR5001 4.0 43.4 1.0
CD D:GLU3893 4.3 44.1 1.0
O D:HIS5003 4.4 38.2 1.0
CA D:THR5001 4.6 43.4 1.0
C D:GLU3893 4.6 44.1 1.0
OE2 D:GLU3893 4.7 44.1 1.0
CD D:GLN3970 4.8 40.5 1.0
N D:GLU5002 4.8 42.9 1.0
CG D:GLU3967 4.9 41.4 1.0
CB D:THR5001 5.0 43.4 1.0

Reference:

W.Risheng, Q.Chen, Z.Lei, L.Chuang, Y.Chang-Cheng, H.Hu. Structural Insights Into Transmembrane Helix TM0 Facilitated RYR1 Channel Gating By CA2+/Atp To Be Published.
Page generated: Thu Jul 10 08:18:05 2025

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