Calcium in PDB 9ctq: BEST1 + Gaba Open State

The binding sites of Calcium atom in the BEST1 + Gaba Open State (pdb code 9ctq). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 5 binding sites of Calcium where determined in the BEST1 + Gaba Open State, PDB code: 9ctq:
Jump to Calcium binding site number: 1; 2; 3; 4; 5;

Calcium binding site 1 out of 5 in the BEST1 + Gaba Open State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of BEST1 + Gaba Open State within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca601 b:28.8 occ:1.00 O D:ASN296 2.3 37.9 1.0 OD2 D:ASP301 2.4 41.0 1.0 O E:ALA10 2.5 36.4 1.0 OD2 D:ASP304 2.5 29.3 1.0 O D:GLN293 2.6 41.4 1.0 OD1 D:ASP304 2.7 42.8 1.0 CG D:ASP304 3.0 30.3 1.0 C D:ASN296 3.4 28.7 1.0 CG D:ASP301 3.5 40.8 1.0 C E:ALA10 3.6 36.5 1.0 C D:GLN293 3.7 34.1 1.0 CB D:ASP301 4.1 39.9 1.0 N D:GLY299 4.1 30.7 1.0 CA D:GLN293 4.2 32.3 1.0 CA D:GLY299 4.3 26.6 1.0 CA D:ASN296 4.3 30.3 1.0 N D:PRO297 4.3 33.4 1.0 CA D:PRO297 4.3 27.5 1.0 N D:ASN296 4.4 37.8 1.0 CA E:ASN11 4.4 36.9 1.0 N E:ASN11 4.4 45.5 1.0 CB D:ASN296 4.5 25.0 1.0 O E:VAL9 4.5 42.2 1.0 CB D:ASP304 4.5 26.5 1.0 OD1 D:ASP301 4.5 51.0 1.0 O D:GLU292 4.6 51.3 1.0 CA E:ALA10 4.6 36.2 1.0 C D:PRO297 4.7 26.9 1.0 N D:ASP301 4.7 36.2 1.0 CG D:GLN293 4.7 45.5 1.0 N D:LEU294 4.8 28.4 1.0 N D:PHE298 4.9 33.1 1.0 N E:ALA12 4.9 47.0 1.0 C D:GLY299 4.9 36.3 1.0 C E:ASN11 4.9 41.1 1.0 N D:GLU300 5.0 40.7 1.0

Calcium binding site 2 out of 5 in the BEST1 + Gaba Open State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of BEST1 + Gaba Open State within 5.0Å range: probe atom residue distance (Å) B Occ E:Ca601 b:31.0 occ:1.00 O E:ASN296 2.3 38.2 1.0 OD2 E:ASP301 2.4 44.1 1.0 O A:ALA10 2.5 35.4 1.0 OD2 E:ASP304 2.5 30.4 1.0 O E:GLN293 2.6 42.7 1.0 OD1 E:ASP304 2.7 44.8 1.0 CG E:ASP304 3.0 31.2 1.0 C E:ASN296 3.4 30.7 1.0 CG E:ASP301 3.5 40.5 1.0 C A:ALA10 3.6 39.2 1.0 C E:GLN293 3.7 35.9 1.0 CB E:ASP301 4.1 38.8 1.0 N E:GLY299 4.1 30.6 1.0 CA E:GLN293 4.2 32.8 1.0 CA E:GLY299 4.3 27.7 1.0 CA E:ASN296 4.3 28.8 1.0 N E:PRO297 4.3 31.9 1.0 CA E:PRO297 4.3 28.5 1.0 N E:ASN296 4.4 32.5 1.0 CA A:ASN11 4.4 36.0 1.0 N A:ASN11 4.4 47.8 1.0 CB E:ASN296 4.5 24.3 1.0 O A:VAL9 4.5 40.4 1.0 CB E:ASP304 4.5 26.4 1.0 OD1 E:ASP301 4.5 50.0 1.0 O E:GLU292 4.6 51.5 1.0 CA A:ALA10 4.6 36.3 1.0 C E:PRO297 4.7 27.3 1.0 N E:ASP301 4.7 35.0 1.0 CG E:GLN293 4.7 43.3 1.0 N E:LEU294 4.8 28.3 1.0 N E:PHE298 4.9 33.0 1.0 N A:ALA12 4.9 44.9 1.0 C E:GLY299 4.9 34.9 1.0 C A:ASN11 4.9 40.1 1.0 N E:GLU300 5.0 39.1 1.0

Calcium binding site 3 out of 5 in the BEST1 + Gaba Open State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of BEST1 + Gaba Open State within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca601 b:29.5 occ:1.00 O C:ASN296 2.3 36.3 1.0 OD2 C:ASP301 2.4 41.5 1.0 O D:ALA10 2.4 35.5 1.0 OD2 C:ASP304 2.5 33.4 1.0 O C:GLN293 2.6 41.4 1.0 OD1 C:ASP304 2.7 43.7 1.0 CG C:ASP304 3.0 30.8 1.0 C C:ASN296 3.4 25.8 1.0 CG C:ASP301 3.5 42.3 1.0 C D:ALA10 3.6 35.2 1.0 C C:GLN293 3.7 33.8 1.0 CB C:ASP301 4.1 40.1 1.0 N C:GLY299 4.1 29.1 1.0 CA C:GLN293 4.2 31.6 1.0 CA C:GLY299 4.3 21.8 1.0 CA C:ASN296 4.3 29.5 1.0 N C:PRO297 4.3 30.9 1.0 CA C:PRO297 4.3 27.0 1.0 CA D:ASN11 4.4 34.1 1.0 N C:ASN296 4.4 31.8 1.0 N D:ASN11 4.4 44.9 1.0 CB C:ASN296 4.5 27.9 1.0 O D:VAL9 4.5 44.3 1.0 CB C:ASP304 4.5 26.8 1.0 OD1 C:ASP301 4.5 51.5 1.0 O C:GLU292 4.6 52.5 1.0 CA D:ALA10 4.6 34.0 1.0 C C:PRO297 4.7 27.3 1.0 N C:ASP301 4.7 34.2 1.0 CG C:GLN293 4.7 42.1 1.0 N C:LEU294 4.8 26.1 1.0 N C:PHE298 4.9 32.8 1.0 N D:ALA12 4.9 44.6 1.0 C C:GLY299 4.9 33.4 1.0 C D:ASN11 4.9 38.4 1.0 N C:GLU300 5.0 39.8 1.0

Calcium binding site 4 out of 5 in the BEST1 + Gaba Open State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of BEST1 + Gaba Open State within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca601 b:30.2 occ:1.00 O B:ASN296 2.3 38.3 1.0 OD2 B:ASP301 2.4 43.2 1.0 O C:ALA10 2.5 36.7 1.0 OD2 B:ASP304 2.5 30.5 1.0 O B:GLN293 2.6 42.1 1.0 OD1 B:ASP304 2.7 48.4 1.0 CG B:ASP304 3.0 34.7 1.0 C B:ASN296 3.4 27.7 1.0 CG B:ASP301 3.5 42.5 1.0 C C:ALA10 3.6 35.6 1.0 C B:GLN293 3.7 35.3 1.0 CB B:ASP301 4.1 40.1 1.0 N B:GLY299 4.1 30.2 1.0 CA B:GLN293 4.2 32.6 1.0 CA B:GLY299 4.3 29.1 1.0 CA B:ASN296 4.3 30.5 1.0 N B:PRO297 4.3 33.3 1.0 CA B:PRO297 4.3 28.3 1.0 N B:ASN296 4.4 35.0 1.0 CA C:ASN11 4.4 34.4 1.0 N C:ASN11 4.4 43.8 1.0 CB B:ASN296 4.5 26.2 1.0 O C:VAL9 4.5 45.4 1.0 CB B:ASP304 4.5 27.0 1.0 OD1 B:ASP301 4.5 50.9 1.0 O B:GLU292 4.6 49.7 1.0 CA C:ALA10 4.6 34.2 1.0 C B:PRO297 4.7 24.7 1.0 N B:ASP301 4.7 37.6 1.0 CG B:GLN293 4.7 43.9 1.0 N B:LEU294 4.8 29.6 1.0 N B:PHE298 4.9 34.3 1.0 N C:ALA12 4.9 46.1 1.0 C B:GLY299 4.9 37.3 1.0 C C:ASN11 4.9 41.0 1.0 N B:GLU300 5.0 38.5 1.0

Calcium binding site 5 out of 5 in the BEST1 + Gaba Open State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of BEST1 + Gaba Open State within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca601 b:29.0 occ:1.00 O A:ASN296 2.3 38.2 1.0 OD2 A:ASP301 2.4 40.5 1.0 O B:ALA10 2.4 33.1 1.0 OD2 A:ASP304 2.5 31.7 1.0 O A:GLN293 2.6 43.2 1.0 OD1 A:ASP304 2.7 44.3 1.0 CG A:ASP304 3.0 33.6 1.0 C A:ASN296 3.4 30.0 1.0 CG A:ASP301 3.5 40.1 1.0 C B:ALA10 3.6 36.0 1.0 C A:GLN293 3.7 34.1 1.0 CB A:ASP301 4.1 38.3 1.0 N A:GLY299 4.1 31.6 1.0 CA A:GLN293 4.2 30.8 1.0 CA A:GLY299 4.3 25.7 1.0 CA A:ASN296 4.3 29.3 1.0 N A:PRO297 4.3 34.0 1.0 CA A:PRO297 4.3 26.8 1.0 CA B:ASN11 4.4 33.8 1.0 N A:ASN296 4.4 34.3 1.0 N B:ASN11 4.4 45.6 1.0 CB A:ASN296 4.5 28.4 1.0 O B:VAL9 4.5 41.0 1.0 CB A:ASP304 4.5 27.6 1.0 OD1 A:ASP301 4.5 48.9 1.0 O A:GLU292 4.6 52.1 1.0 CA B:ALA10 4.6 35.4 1.0 C A:PRO297 4.7 27.7 1.0 N A:ASP301 4.7 35.4 1.0 CG A:GLN293 4.7 42.3 1.0 N A:LEU294 4.8 26.4 1.0 N A:PHE298 4.9 31.0 1.0 N B:ALA12 4.9 46.5 1.0 C A:GLY299 4.9 33.2 1.0 C B:ASN11 4.9 40.2 1.0 N A:GLU300 5.0 40.0 1.0

J.Wang, A.P.Owji, A.Kittredge, Z.Clark, Y.Zhang, T.Yang. GAD65 Tunes the Functions of BEST1 As A Gaba Receptor and A Neurotransmitter Conducting Channel. Nat Commun V. 15 8051 2024.
ISSN: ESSN 2041-1723
PubMed: 39277606
DOI: 10.1038/S41467-024-52039-5