Calcium in PDB 9ctr: BEST1 + Gaba Intermediate State 1

The binding sites of Calcium atom in the BEST1 + Gaba Intermediate State 1 (pdb code 9ctr). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 5 binding sites of Calcium where determined in the BEST1 + Gaba Intermediate State 1, PDB code: 9ctr:
Jump to Calcium binding site number: 1; 2; 3; 4; 5;

Calcium binding site 1 out of 5 in the BEST1 + Gaba Intermediate State 1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of BEST1 + Gaba Intermediate State 1 within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca601 b:44.5 occ:1.00 O B:ASN296 2.2 50.5 1.0 OD2 B:ASP301 2.4 62.8 1.0 O C:ALA10 2.5 52.0 1.0 OD2 B:ASP304 2.7 54.1 1.0 O B:GLN293 2.7 56.6 1.0 OD1 B:ASP304 2.8 58.5 1.0 CG B:ASP304 3.1 52.0 1.0 C B:ASN296 3.4 40.5 1.0 CG B:ASP301 3.5 60.5 1.0 C C:ALA10 3.6 46.6 1.0 C B:GLN293 3.7 49.4 1.0 CB B:ASP301 4.1 58.0 1.0 CA B:ASN296 4.2 38.9 1.0 N B:GLY299 4.2 48.6 1.0 CB B:ASN296 4.2 37.6 1.0 CA B:GLN293 4.3 47.9 1.0 N B:ASN296 4.3 48.9 1.0 N B:PRO297 4.3 42.2 1.0 CA C:ASN11 4.3 48.6 1.0 CA B:GLY299 4.4 42.5 1.0 CA B:PRO297 4.4 38.1 1.0 N C:ASN11 4.4 56.5 1.0 O C:VAL9 4.5 57.6 1.0 OD1 B:ASP301 4.5 66.9 1.0 O B:GLU292 4.6 63.4 1.0 CB B:ASP304 4.6 43.2 1.0 CA C:ALA10 4.6 45.0 1.0 CG B:GLN293 4.7 55.6 1.0 C B:PRO297 4.7 35.9 1.0 N B:ASP301 4.7 57.7 1.0 N C:ALA12 4.8 51.7 1.0 N B:LEU294 4.9 44.0 1.0 C C:ASN11 4.9 50.8 1.0 N B:PHE298 4.9 40.3 1.0 OD1 C:ASN11 5.0 60.5 1.0

Calcium binding site 2 out of 5 in the BEST1 + Gaba Intermediate State 1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of BEST1 + Gaba Intermediate State 1 within 5.0Å range: probe atom residue distance (Å) B Occ E:Ca601 b:44.8 occ:1.00 O E:ASN296 2.2 52.5 1.0 OD2 E:ASP301 2.4 57.9 1.0 OD2 E:ASP304 2.5 53.1 1.0 O A:ALA10 2.5 51.7 1.0 O E:GLN293 2.6 52.0 1.0 OD1 E:ASP304 2.7 57.6 1.0 CG E:ASP304 2.9 49.6 1.0 C E:ASN296 3.4 45.1 1.0 CG E:ASP301 3.5 57.1 1.0 C A:ALA10 3.7 49.4 1.0 C E:GLN293 3.7 46.8 1.0 CB E:ASP301 4.0 54.4 1.0 N E:GLY299 4.2 54.1 1.0 CA E:PRO297 4.2 36.3 1.0 N E:PRO297 4.3 44.7 1.0 CA E:GLN293 4.3 45.2 1.0 CA E:ASN296 4.3 37.7 1.0 CA E:GLY299 4.3 50.3 1.0 CA A:ASN11 4.3 48.3 1.0 N E:ASN296 4.4 46.0 1.0 CB E:ASP304 4.4 43.4 1.0 CB E:ASN296 4.4 39.7 1.0 N A:ASN11 4.5 54.7 1.0 OD1 E:ASP301 4.6 63.9 1.0 C E:PRO297 4.6 42.7 1.0 O A:VAL9 4.6 57.8 1.0 CG E:GLN293 4.6 53.5 1.0 N E:ASP301 4.7 55.0 1.0 O E:GLU292 4.7 65.2 1.0 CA A:ALA10 4.7 47.3 1.0 N E:LEU294 4.8 43.6 1.0 N E:PHE298 4.8 49.5 1.0 C E:GLY299 4.9 51.4 1.0 N A:ALA12 4.9 59.8 1.0 C A:ASN11 5.0 54.3 1.0 OD1 A:ASN11 5.0 61.2 1.0 CA E:ASP301 5.0 52.1 1.0

Calcium binding site 3 out of 5 in the BEST1 + Gaba Intermediate State 1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of BEST1 + Gaba Intermediate State 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca601 b:44.6 occ:1.00 O A:ASN296 2.2 45.8 1.0 O B:ALA10 2.4 55.3 1.0 OD2 A:ASP304 2.6 54.4 1.0 OD2 A:ASP301 2.6 56.6 1.0 O A:GLN293 2.7 55.6 1.0 OD1 A:ASP304 2.9 59.4 1.0 CG A:ASP304 3.1 52.3 1.0 C A:ASN296 3.4 40.6 1.0 C B:ALA10 3.6 51.9 1.0 CG A:ASP301 3.7 60.4 1.0 C A:GLN293 3.8 44.6 1.0 CB A:ASP301 4.1 58.2 1.0 N A:GLY299 4.2 44.5 1.0 CA A:ASN296 4.2 39.9 1.0 CA B:ASN11 4.2 51.2 1.0 CB A:ASN296 4.3 34.3 1.0 CA A:GLN293 4.3 43.4 1.0 N A:PRO297 4.3 38.8 1.0 N A:ASN296 4.3 48.2 1.0 N B:ASN11 4.3 61.9 1.0 CA A:GLY299 4.3 40.7 1.0 CA A:PRO297 4.3 34.2 1.0 O B:VAL9 4.4 52.5 1.0 CA B:ALA10 4.6 47.1 1.0 CB A:ASP304 4.6 44.4 1.0 O A:GLU292 4.7 63.1 1.0 CG A:GLN293 4.7 54.5 1.0 OD1 A:ASP301 4.7 63.5 1.0 C A:PRO297 4.7 42.5 1.0 N A:ASP301 4.8 49.3 1.0 C B:ASN11 4.9 55.6 1.0 N A:PHE298 4.9 48.5 1.0 N B:ALA12 4.9 59.5 1.0 N A:LEU294 4.9 43.2 1.0 OD1 B:ASN11 4.9 65.3 1.0 C A:GLY299 4.9 48.4 1.0

Calcium binding site 4 out of 5 in the BEST1 + Gaba Intermediate State 1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of BEST1 + Gaba Intermediate State 1 within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca601 b:47.8 occ:1.00 O D:ASN296 2.2 50.1 1.0 OD2 D:ASP301 2.3 64.3 1.0 O E:ALA10 2.4 47.9 1.0 O D:GLN293 2.8 59.1 1.0 OD2 D:ASP304 2.8 50.0 1.0 OD1 D:ASP304 2.9 59.2 1.0 CG D:ASP304 3.2 47.3 1.0 C D:ASN296 3.4 40.8 1.0 CG D:ASP301 3.4 60.1 1.0 C E:ALA10 3.6 49.4 1.0 C D:GLN293 3.8 53.1 1.0 CB D:ASP301 4.0 56.6 1.0 CA D:ASN296 4.2 38.1 1.0 N D:GLY299 4.2 49.3 1.0 CB D:ASN296 4.3 38.7 1.0 CA E:ASN11 4.3 54.9 1.0 N D:PRO297 4.3 39.3 1.0 CA D:GLN293 4.3 43.1 1.0 N D:ASN296 4.3 45.4 1.0 N E:ASN11 4.3 57.0 1.0 CA D:PRO297 4.3 38.5 1.0 O E:VAL9 4.4 58.2 1.0 OD1 D:ASP301 4.4 67.1 1.0 CA D:GLY299 4.4 42.1 1.0 CA E:ALA10 4.5 50.8 1.0 O D:GLU292 4.6 63.8 1.0 CB D:ASP304 4.7 49.1 1.0 C D:PRO297 4.7 42.0 1.0 N D:ASP301 4.7 59.0 1.0 CG D:GLN293 4.8 53.0 1.0 C E:ASN11 4.9 55.8 1.0 N D:PHE298 4.9 47.6 1.0 N E:ALA12 4.9 58.3 1.0 N D:LEU294 5.0 45.0 1.0 OD1 E:ASN11 5.0 61.7 1.0

Calcium binding site 5 out of 5 in the BEST1 + Gaba Intermediate State 1


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of BEST1 + Gaba Intermediate State 1 within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca601 b:50.1 occ:1.00 O C:ASN296 2.3 51.6 1.0 OD2 C:ASP301 2.3 62.9 1.0 OD2 C:ASP304 2.4 53.7 1.0 O D:ALA10 2.6 57.1 1.0 OD1 C:ASP304 2.6 59.5 1.0 O C:GLN293 2.7 53.8 1.0 CG C:ASP304 2.9 54.0 1.0 CG C:ASP301 3.4 62.1 1.0 C C:ASN296 3.4 46.1 1.0 C D:ALA10 3.8 57.1 1.0 C C:GLN293 3.8 50.2 1.0 CB C:ASP301 4.0 55.8 1.0 N C:GLY299 4.2 51.3 1.0 CA C:GLN293 4.3 46.5 1.0 CA C:ASN296 4.3 46.6 1.0 N C:PRO297 4.3 37.4 1.0 CA C:GLY299 4.3 47.7 1.0 CA C:PRO297 4.4 37.1 1.0 CB C:ASN296 4.4 39.4 1.0 CB C:ASP304 4.4 48.4 1.0 OD1 C:ASP301 4.4 69.9 1.0 CA D:ASN11 4.4 55.1 1.0 N C:ASN296 4.4 49.2 1.0 N D:ASN11 4.5 62.8 1.0 O D:VAL9 4.6 62.2 1.0 CG C:GLN293 4.6 56.4 1.0 N C:ASP301 4.6 58.4 1.0 C C:PRO297 4.7 45.2 1.0 O C:GLU292 4.7 64.1 1.0 CA D:ALA10 4.8 55.2 1.0 N C:PHE298 4.8 49.6 1.0 N C:LEU294 4.9 45.9 1.0 C C:GLY299 4.9 49.3 1.0 N C:GLU300 5.0 60.8 1.0 N D:ALA12 5.0 57.2 1.0 CA C:ASP301 5.0 58.0 1.0 OD1 D:ASN11 5.0 66.3 1.0 C D:ASN11 5.0 59.3 1.0

J.Wang, A.P.Owji, A.Kittredge, Z.Clark, Y.Zhang, T.Yang. GAD65 Tunes the Functions of BEST1 As A Gaba Receptor and A Neurotransmitter Conducting Channel. Nat Commun V. 15 8051 2024.
ISSN: ESSN 2041-1723
PubMed: 39277606
DOI: 10.1038/S41467-024-52039-5