Calcium in PDB 9cts: BEST1 + Gaba Intermediate State 2

The binding sites of Calcium atom in the BEST1 + Gaba Intermediate State 2 (pdb code 9cts). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 5 binding sites of Calcium where determined in the BEST1 + Gaba Intermediate State 2, PDB code: 9cts:
Jump to Calcium binding site number: 1; 2; 3; 4; 5;

Calcium binding site 1 out of 5 in the BEST1 + Gaba Intermediate State 2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of BEST1 + Gaba Intermediate State 2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca601 b:46.8 occ:1.00 O B:ASN296 2.3 48.5 1.0 O C:ALA10 2.4 52.4 1.0 OD2 B:ASP301 2.5 55.8 1.0 O B:GLN293 2.7 52.4 1.0 OD2 B:ASP304 2.7 52.6 1.0 OD1 B:ASP304 2.9 52.6 1.0 CG B:ASP304 3.2 52.6 1.0 C B:ASN296 3.4 48.5 1.0 C C:ALA10 3.6 52.4 1.0 CG B:ASP301 3.6 55.8 1.0 C B:GLN293 3.7 52.4 1.0 CB B:ASP301 4.0 55.8 1.0 CA B:GLN293 4.1 52.4 1.0 CA C:ASN11 4.2 55.8 1.0 CA B:ASN296 4.2 48.5 1.0 CB B:ASN296 4.3 48.5 1.0 N B:ASN296 4.3 48.5 1.0 N C:ASN11 4.3 55.8 1.0 O C:VAL9 4.3 51.8 1.0 N B:GLY299 4.4 51.4 1.0 N B:PRO297 4.4 47.3 1.0 CA B:PRO297 4.4 47.3 1.0 CA B:GLY299 4.5 51.4 1.0 CG B:GLN293 4.6 52.4 1.0 CA C:ALA10 4.6 52.4 1.0 O B:GLU292 4.6 53.6 1.0 OD1 B:ASP301 4.6 55.8 1.0 CB B:ASP304 4.7 52.6 1.0 N C:ALA12 4.8 58.0 1.0 C C:ASN11 4.8 55.8 1.0 N B:ASP301 4.8 55.8 1.0 OD1 C:ASN11 4.8 55.8 1.0 C B:PRO297 4.8 47.3 1.0 N B:LEU294 4.8 47.4 1.0 CB B:GLN293 5.0 52.4 1.0

Calcium binding site 2 out of 5 in the BEST1 + Gaba Intermediate State 2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of BEST1 + Gaba Intermediate State 2 within 5.0Å range: probe atom residue distance (Å) B Occ E:Ca601 b:47.6 occ:1.00 O E:ASN296 2.3 45.9 1.0 OD2 E:ASP301 2.4 52.0 1.0 O A:ALA10 2.5 45.5 1.0 OD2 E:ASP304 2.6 50.4 1.0 O E:GLN293 2.6 50.8 1.0 OD1 E:ASP304 2.8 50.4 1.0 CG E:ASP304 3.0 50.4 1.0 C E:ASN296 3.4 45.9 1.0 CG E:ASP301 3.5 52.0 1.0 C A:ALA10 3.6 45.5 1.0 C E:GLN293 3.7 50.8 1.0 CB E:ASP301 4.0 52.0 1.0 N E:GLY299 4.2 49.7 1.0 CA E:GLN293 4.3 50.8 1.0 CA A:ASN11 4.3 48.0 1.0 CA E:ASN296 4.3 45.9 1.0 CA E:GLY299 4.3 49.7 1.0 N E:PRO297 4.3 45.9 1.0 CA E:PRO297 4.3 45.9 1.0 N A:ASN11 4.4 48.0 1.0 CB E:ASN296 4.4 45.9 1.0 N E:ASN296 4.4 45.9 1.0 OD1 E:ASP301 4.5 52.0 1.0 O A:VAL9 4.5 43.6 1.0 CB E:ASP304 4.6 50.4 1.0 CG E:GLN293 4.6 50.8 1.0 CA A:ALA10 4.6 45.5 1.0 N E:ASP301 4.7 52.0 1.0 C E:PRO297 4.7 45.9 1.0 O E:GLU292 4.7 50.3 1.0 N A:ALA12 4.8 49.2 1.0 N E:LEU294 4.9 46.9 1.0 C A:ASN11 4.9 48.0 1.0 N E:PHE298 4.9 47.0 1.0 C E:GLY299 4.9 49.7 1.0 N E:GLU300 5.0 53.1 1.0 OD1 A:ASN11 5.0 48.0 1.0

Calcium binding site 3 out of 5 in the BEST1 + Gaba Intermediate State 2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of BEST1 + Gaba Intermediate State 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca602 b:42.4 occ:1.00 O A:ASN296 2.3 39.7 1.0 OD2 A:ASP301 2.3 44.0 1.0 O B:ALA10 2.4 43.9 1.0 O A:GLN293 2.6 43.1 1.0 OD2 A:ASP304 2.7 41.1 1.0 OD1 A:ASP304 2.9 41.1 1.0 CG A:ASP304 3.2 41.1 1.0 C A:ASN296 3.4 39.7 1.0 CG A:ASP301 3.5 44.0 1.0 C B:ALA10 3.6 43.9 1.0 C A:GLN293 3.7 43.1 1.0 CB A:ASP301 4.1 44.0 1.0 CA A:ASN296 4.2 39.7 1.0 CA A:GLN293 4.2 43.1 1.0 N A:GLY299 4.2 41.6 1.0 CB A:ASN296 4.3 39.7 1.0 N A:ASN296 4.3 39.7 1.0 CA B:ASN11 4.3 45.9 1.0 N A:PRO297 4.3 37.7 1.0 N B:ASN11 4.4 45.9 1.0 CA A:PRO297 4.4 37.7 1.0 CA A:GLY299 4.4 41.6 1.0 O B:VAL9 4.4 44.9 1.0 OD1 A:ASP301 4.4 44.0 1.0 O A:GLU292 4.6 43.9 1.0 CA B:ALA10 4.6 43.9 1.0 CG A:GLN293 4.7 43.1 1.0 CB A:ASP304 4.7 41.1 1.0 C A:PRO297 4.8 37.7 1.0 N A:ASP301 4.8 44.0 1.0 N A:LEU294 4.8 39.1 1.0 C B:ASN11 4.8 45.9 1.0 N B:ALA12 4.9 48.6 1.0 N A:PHE298 4.9 38.0 1.0 CG A:ASN296 5.0 39.7 1.0

Calcium binding site 4 out of 5 in the BEST1 + Gaba Intermediate State 2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of BEST1 + Gaba Intermediate State 2 within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca601 b:49.0 occ:1.00 O D:ASN296 2.3 48.5 1.0 OD2 D:ASP301 2.4 55.7 1.0 OD2 D:ASP304 2.5 52.8 1.0 O E:ALA10 2.6 52.6 1.0 O D:GLN293 2.6 54.0 1.0 OD1 D:ASP304 2.8 52.8 1.0 CG D:ASP304 3.0 52.8 1.0 C D:ASN296 3.4 48.5 1.0 CG D:ASP301 3.4 55.7 1.0 C D:GLN293 3.7 54.0 1.0 C E:ALA10 3.8 52.6 1.0 CB D:ASP301 4.0 55.7 1.0 N D:GLY299 4.2 51.4 1.0 CA D:GLN293 4.2 54.0 1.0 CA D:ASN296 4.3 48.5 1.0 CA D:GLY299 4.3 51.4 1.0 N D:PRO297 4.3 47.4 1.0 N D:ASN296 4.4 48.5 1.0 CA D:PRO297 4.4 47.4 1.0 CB D:ASN296 4.4 48.5 1.0 CA E:ASN11 4.4 56.6 1.0 OD1 D:ASP301 4.5 55.7 1.0 CB D:ASP304 4.5 52.8 1.0 N E:ASN11 4.5 56.6 1.0 CG D:GLN293 4.5 54.0 1.0 O E:VAL9 4.6 52.4 1.0 N D:ASP301 4.6 55.7 1.0 O D:GLU292 4.7 56.4 1.0 C D:PRO297 4.7 47.4 1.0 CA E:ALA10 4.8 52.6 1.0 N D:LEU294 4.8 49.9 1.0 C D:GLY299 4.9 51.4 1.0 N D:PHE298 4.9 48.2 1.0 N D:GLU300 4.9 56.1 1.0 N E:ALA12 4.9 58.6 1.0 CA D:ASP301 5.0 55.7 1.0 OD1 E:ASN11 5.0 56.6 1.0

Calcium binding site 5 out of 5 in the BEST1 + Gaba Intermediate State 2


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of BEST1 + Gaba Intermediate State 2 within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca601 b:49.6 occ:1.00 O C:ASN296 2.4 47.0 1.0 OD2 C:ASP301 2.4 55.5 1.0 O D:ALA10 2.4 50.5 1.0 OD2 C:ASP304 2.6 52.5 1.0 O C:GLN293 2.7 53.6 1.0 OD1 C:ASP304 2.8 52.5 1.0 CG C:ASP304 3.1 52.5 1.0 CG C:ASP301 3.4 55.5 1.0 C C:ASN296 3.5 47.0 1.0 C D:ALA10 3.6 50.5 1.0 C C:GLN293 3.8 53.6 1.0 CB C:ASP301 3.9 55.5 1.0 N C:GLY299 4.2 51.4 1.0 CA C:GLN293 4.2 53.6 1.0 CA D:ASN11 4.3 54.0 1.0 CA C:GLY299 4.3 51.4 1.0 CA C:ASN296 4.3 47.0 1.0 N D:ASN11 4.4 54.0 1.0 CB C:ASN296 4.4 47.0 1.0 N C:PRO297 4.4 47.1 1.0 CA C:PRO297 4.4 47.1 1.0 N C:ASN296 4.5 47.0 1.0 OD1 C:ASP301 4.5 55.5 1.0 O D:VAL9 4.5 50.6 1.0 CB C:ASP304 4.6 52.5 1.0 CG C:GLN293 4.6 53.6 1.0 CA D:ALA10 4.6 50.5 1.0 O C:GLU292 4.6 53.4 1.0 N C:ASP301 4.7 55.5 1.0 C C:PRO297 4.8 47.1 1.0 N D:ALA12 4.8 56.4 1.0 C D:ASN11 4.9 54.0 1.0 N C:LEU294 4.9 48.2 1.0 C C:GLY299 4.9 51.4 1.0 N C:PHE298 5.0 47.9 1.0 CA C:ASP301 5.0 55.5 1.0 OD1 D:ASN11 5.0 54.0 1.0

J.Wang, A.P.Owji, A.Kittredge, Z.Clark, Y.Zhang, T.Yang. GAD65 Tunes the Functions of BEST1 As A Gaba Receptor and A Neurotransmitter Conducting Channel. Nat Commun V. 15 8051 2024.
ISSN: ESSN 2041-1723
PubMed: 39277606
DOI: 10.1038/S41467-024-52039-5