Calcium in PDB 9g77: Mouse Mitochondrial Dna Polymerase Gamma Ternary Complex in Error- Editing Conformer (Composite)

All present enzymatic activity of Mouse Mitochondrial Dna Polymerase Gamma Ternary Complex in Error- Editing Conformer (Composite):
2.7.7.7;

The binding sites of Calcium atom in the Mouse Mitochondrial Dna Polymerase Gamma Ternary Complex in Error- Editing Conformer (Composite) (pdb code 9g77). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Mouse Mitochondrial Dna Polymerase Gamma Ternary Complex in Error- Editing Conformer (Composite), PDB code: 9g77:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Mouse Mitochondrial Dna Polymerase Gamma Ternary Complex in Error- Editing Conformer (Composite)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Mouse Mitochondrial Dna Polymerase Gamma Ternary Complex in Error- Editing Conformer (Composite) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1300 b:134.0 occ:1.00 OD2 A:ASP868 2.4 62.7 1.0 CG A:ASP868 2.8 63.3 1.0 O A:VAL869 2.8 59.4 1.0 OD1 A:ASP868 2.9 68.2 1.0 OD2 A:ASP1113 3.3 73.4 1.0 C A:VAL869 3.9 54.7 1.0 CB A:ASP868 4.0 50.8 1.0 CG A:ASP1113 4.0 68.8 1.0 O3A A:DCP1301 4.0 102.5 1.0 OD1 A:ASP1113 4.1 68.5 1.0 O1B A:DCP1301 4.4 101.0 1.0 CA A:ASP870 4.4 68.5 1.0 N A:VAL869 4.5 47.7 1.0 C A:ASP868 4.5 49.4 1.0 N A:ASP870 4.5 69.7 1.0 OD1 A:ASP870 4.6 73.5 1.0 O1A A:DCP1301 4.6 101.7 1.0 PB A:DCP1301 4.8 100.7 1.0 O A:ASP868 4.8 58.0 1.0 N A:SER871 4.8 73.3 1.0 CA A:ASP868 4.8 43.9 1.0 CA A:VAL869 4.8 47.4 1.0 O3B A:DCP1301 4.9 100.3 1.0 PA A:DCP1301 4.9 105.9 1.0 C5' A:DCP1301 4.9 100.2 1.0 O5' A:DCP1301 5.0 101.2 1.0

Calcium binding site 2 out of 2 in the Mouse Mitochondrial Dna Polymerase Gamma Ternary Complex in Error- Editing Conformer (Composite)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Mouse Mitochondrial Dna Polymerase Gamma Ternary Complex in Error- Editing Conformer (Composite) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1302 b:88.8 occ:1.00 OD2 A:ASP257 2.5 67.9 1.0 O A:HIS252 2.7 61.5 1.0 O3' P:DC24 2.7 130.0 1.0 CG A:ASP257 3.2 69.5 1.0 OD1 A:ASP257 3.2 72.6 1.0 OP1 P:DT25 3.3 113.6 1.0 OD1 A:ASP181 3.4 85.5 1.0 C4' P:DC24 3.7 128.8 1.0 P P:DT25 3.7 115.8 1.0 C3' P:DC24 3.8 130.4 1.0 C A:HIS252 3.9 54.9 1.0 O A:ASN253 4.0 49.2 1.0 CG A:ASP181 4.4 85.1 1.0 C A:ASN253 4.4 43.6 1.0 C5' P:DC24 4.4 130.2 1.0 C2' P:DC24 4.5 129.4 1.0 CB A:ASP257 4.6 62.6 1.0 CD2 A:PHE256 4.6 70.1 1.0 O5' P:DT25 4.6 118.0 1.0 CA A:ASP181 4.6 83.1 1.0 N A:HIS252 4.6 36.7 1.0 CB A:ASN253 4.7 48.6 1.0 O4' P:DC24 4.8 127.5 1.0 N A:VAL182 4.8 75.6 1.0 OP2 P:DT25 4.8 113.5 1.0 CA A:HIS252 4.8 34.0 1.0 O A:PHE180 4.8 69.2 1.0 N A:ASN253 4.9 58.5 1.0 CA A:ASN253 4.9 41.2 1.0 C1' P:DC24 5.0 127.8 1.0

S.Corra, A.Zuppardo, S.Valenzuela, L.Jenninger, R.Cerutti, S.Sillamaa, E.Hoberg, K.A.S.Johansson, U.Rovsnik, S.Volta, P.Silva-Pinheiro, H.Davis, A.Trifunovic, M.Minczuk, C.M.Gustafsson, A.Suomalainen, M.Zeviani, B.Macao, X.Zhu, M.Falkenberg, C.Viscomi. Modelling Polg Mutations in Mice Unravels A Critical Role of Pol Gamma Beta in Regulating Phenotypic Severity. Nat Commun V. 16 4782 2025.
ISSN: ESSN 2041-1723
PubMed: 40404629
DOI: 10.1038/S41467-025-60059-Y