Calcium in PDB 9gy0: CRYO_EM Structure of Human FAN1 R507H Mutant in Complex with 5' Flap Dna Substrate and Pcna

All present enzymatic activity of CRYO_EM Structure of Human FAN1 R507H Mutant in Complex with 5' Flap Dna Substrate and Pcna:
3.1.4.1;

The binding sites of Calcium atom in the CRYO_EM Structure of Human FAN1 R507H Mutant in Complex with 5' Flap Dna Substrate and Pcna (pdb code 9gy0). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the CRYO_EM Structure of Human FAN1 R507H Mutant in Complex with 5' Flap Dna Substrate and Pcna, PDB code: 9gy0:

Calcium binding site 1 out of 1 in the CRYO_EM Structure of Human FAN1 R507H Mutant in Complex with 5' Flap Dna Substrate and Pcna


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of CRYO_EM Structure of Human FAN1 R507H Mutant in Complex with 5' Flap Dna Substrate and Pcna within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca2000 b:86.9 occ:1.00 OD2 A:ASP960 2.4 68.6 1.0 O A:VAL976 2.8 77.6 1.0 OE2 A:GLU975 3.1 59.2 1.0 CG A:ASP960 3.3 64.0 1.0 OP1 D:DG4 3.4 144.1 1.0 OD1 A:ASP960 3.6 69.3 1.0 NZ A:LYS977 3.8 79.0 1.0 C A:VAL976 4.0 67.7 1.0 CD A:GLU975 4.3 64.5 1.0 OE2 A:GLU834 4.3 109.4 1.0 OE2 A:GLU815 4.5 81.0 1.0 CD A:LYS977 4.6 72.6 1.0 N A:VAL976 4.6 60.0 1.0 P D:DG4 4.6 151.6 1.0 CB A:ASP960 4.7 51.7 1.0 CE A:LYS977 4.7 80.4 1.0 NE2 A:GLN987 4.8 64.5 1.0 CA A:VAL976 4.8 58.1 1.0 N A:LYS977 4.9 68.6 1.0 OE1 A:GLU975 5.0 59.7 1.0 O3' D:DC3 5.0 145.0 1.0 CB A:VAL976 5.0 53.2 1.0

J.Aretz, G.Jeyasankar, A.Salerno-Kochan, M.Thomsen, G.Thieulin-Pardo, T.Haque, E.Monteagudo, D.Felsenfeld, M.Finley, T.F.Vogt, J.Boudet, B.C.Prasad. A FAN1 Point Mutation Associated with Accelerated Huntington'S Disease Progression Alters Its Pcna-Mediated Assembly on Dna Biorxiv 2024.
ISSN: ISSN 2692-8205
DOI: 10.1101/2024.10.09.617442