Calcium in PDB 9o52: Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin
Other elements in 9o52:
The structure of Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin also contains other interesting chemical elements:
Calcium Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
16;
Binding sites:
The binding sites of Calcium atom in the Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin
(pdb code 9o52). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 16 binding sites of Calcium where determined in the
Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin, PDB code: 9o52:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Calcium binding site 1 out
of 16 in 9o52
Go back to
Calcium Binding Sites List in 9o52
Calcium binding site 1 out
of 16 in the Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca501
b:102.8
occ:1.00
|
OE1
|
E:GLU32
|
2.3
|
102.0
|
1.0
|
|
OD1
|
E:ASP25
|
2.3
|
103.8
|
1.0
|
|
OD1
|
E:ASP23
|
2.4
|
102.7
|
1.0
|
|
O
|
E:THR27
|
2.4
|
97.5
|
1.0
|
|
OD1
|
E:ASP21
|
2.5
|
96.1
|
1.0
|
|
CD
|
E:GLU32
|
2.8
|
98.8
|
1.0
|
|
OE2
|
E:GLU32
|
2.8
|
98.3
|
1.0
|
|
OD2
|
E:ASP23
|
2.9
|
109.5
|
1.0
|
|
CG
|
E:ASP23
|
3.0
|
105.0
|
1.0
|
|
CG
|
E:ASP25
|
3.1
|
103.1
|
1.0
|
|
OD2
|
E:ASP25
|
3.4
|
103.3
|
1.0
|
|
OG1
|
E:THR29
|
3.5
|
105.3
|
1.0
|
|
C
|
E:THR27
|
3.6
|
95.8
|
1.0
|
|
CG
|
E:ASP21
|
3.6
|
97.5
|
1.0
|
|
N
|
E:THR29
|
4.0
|
96.2
|
1.0
|
|
OD2
|
E:ASP21
|
4.1
|
101.5
|
1.0
|
|
CG
|
E:GLU32
|
4.2
|
96.2
|
1.0
|
|
CB
|
E:ASP25
|
4.3
|
101.6
|
1.0
|
|
OG1
|
E:THR27
|
4.4
|
97.7
|
1.0
|
|
N
|
E:THR27
|
4.4
|
95.9
|
1.0
|
|
CB
|
E:ASP23
|
4.4
|
102.8
|
1.0
|
|
CA
|
E:ILE28
|
4.5
|
92.8
|
1.0
|
|
N
|
E:ILE28
|
4.5
|
93.4
|
1.0
|
|
N
|
E:ASP25
|
4.5
|
101.8
|
1.0
|
|
CB
|
E:THR29
|
4.5
|
102.9
|
1.0
|
|
CA
|
E:THR27
|
4.6
|
96.4
|
1.0
|
|
C
|
E:ILE28
|
4.8
|
94.1
|
1.0
|
|
N
|
E:ASP23
|
4.8
|
106.0
|
1.0
|
|
CB
|
E:ASP21
|
4.8
|
92.3
|
1.0
|
|
N
|
E:GLY24
|
4.9
|
101.3
|
1.0
|
|
CA
|
E:THR29
|
4.9
|
98.6
|
1.0
|
|
CA
|
E:ASP25
|
4.9
|
101.6
|
1.0
|
|
CA
|
E:ASP21
|
5.0
|
92.0
|
1.0
|
|
Calcium binding site 2 out
of 16 in 9o52
Go back to
Calcium Binding Sites List in 9o52
Calcium binding site 2 out
of 16 in the Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca502
b:111.2
occ:1.00
|
OD1
|
E:ASP59
|
2.3
|
110.6
|
1.0
|
|
OD1
|
E:ASP57
|
2.3
|
103.5
|
1.0
|
|
O
|
E:THR63
|
2.4
|
102.7
|
1.0
|
|
OE1
|
E:GLU68
|
2.4
|
103.0
|
1.0
|
|
OD1
|
E:ASN61
|
2.4
|
108.7
|
1.0
|
|
OE2
|
E:GLU68
|
2.5
|
108.3
|
1.0
|
|
CD
|
E:GLU68
|
2.8
|
104.7
|
1.0
|
|
OD2
|
E:ASP59
|
3.0
|
113.1
|
1.0
|
|
CG
|
E:ASP59
|
3.0
|
112.9
|
1.0
|
|
CG
|
E:ASN61
|
3.1
|
107.4
|
1.0
|
|
ND2
|
E:ASN61
|
3.2
|
109.0
|
1.0
|
|
CG
|
E:ASP57
|
3.5
|
105.2
|
1.0
|
|
C
|
E:THR63
|
3.6
|
99.2
|
1.0
|
|
OD2
|
E:ASP57
|
4.1
|
107.8
|
1.0
|
|
OD1
|
E:ASP65
|
4.2
|
100.9
|
1.0
|
|
N
|
E:ASP65
|
4.2
|
93.6
|
1.0
|
|
CG
|
E:ASP65
|
4.3
|
102.5
|
1.0
|
|
CG
|
E:GLU68
|
4.3
|
99.3
|
1.0
|
|
CA
|
E:ILE64
|
4.4
|
93.9
|
1.0
|
|
N
|
E:ILE64
|
4.4
|
95.6
|
1.0
|
|
N
|
E:THR63
|
4.4
|
103.1
|
1.0
|
|
CB
|
E:ASN61
|
4.5
|
104.4
|
1.0
|
|
OD2
|
E:ASP65
|
4.5
|
99.7
|
1.0
|
|
CB
|
E:ASP59
|
4.5
|
113.5
|
1.0
|
|
OG1
|
E:THR63
|
4.5
|
101.5
|
1.0
|
|
N
|
E:ASN61
|
4.6
|
108.0
|
1.0
|
|
CA
|
E:THR63
|
4.6
|
101.5
|
1.0
|
|
N
|
E:ASP59
|
4.6
|
107.6
|
1.0
|
|
CB
|
E:ASP57
|
4.7
|
107.7
|
1.0
|
|
CA
|
E:ASP57
|
4.7
|
108.5
|
1.0
|
|
C
|
E:ILE64
|
4.8
|
94.9
|
1.0
|
|
N
|
E:GLY60
|
4.9
|
109.1
|
1.0
|
|
CB
|
E:ASP65
|
4.9
|
101.4
|
1.0
|
|
N
|
E:ALA58
|
5.0
|
110.6
|
1.0
|
|
CD1
|
E:ILE64
|
5.0
|
105.1
|
1.0
|
|
Calcium binding site 3 out
of 16 in 9o52
Go back to
Calcium Binding Sites List in 9o52
Calcium binding site 3 out
of 16 in the Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca503
b:144.1
occ:1.00
|
OE1
|
E:GLU105
|
2.3
|
134.2
|
1.0
|
|
O
|
E:TYR100
|
2.3
|
132.3
|
1.0
|
|
OD2
|
E:ASP96
|
2.4
|
134.8
|
1.0
|
|
OD1
|
E:ASP96
|
2.4
|
128.8
|
1.0
|
|
CG
|
E:ASP96
|
2.6
|
131.4
|
1.0
|
|
OD1
|
E:ASP94
|
2.8
|
126.3
|
1.0
|
|
OD1
|
E:ASN98
|
3.0
|
130.7
|
1.0
|
|
CD
|
E:GLU105
|
3.1
|
132.5
|
1.0
|
|
OE2
|
E:GLU105
|
3.1
|
128.9
|
1.0
|
|
C
|
E:TYR100
|
3.4
|
129.6
|
1.0
|
|
CG
|
E:ASP94
|
3.8
|
125.8
|
1.0
|
|
CA
|
E:ILE101
|
3.8
|
129.3
|
1.0
|
|
N
|
E:SER102
|
3.8
|
134.5
|
1.0
|
|
CG
|
E:ASN98
|
3.9
|
129.8
|
1.0
|
|
CB
|
E:ASP96
|
4.0
|
131.5
|
1.0
|
|
N
|
E:ILE101
|
4.0
|
127.9
|
1.0
|
|
OD2
|
E:ASP94
|
4.2
|
129.2
|
1.0
|
|
ND2
|
E:ASN98
|
4.2
|
128.8
|
1.0
|
|
C
|
E:ILE101
|
4.3
|
132.8
|
1.0
|
|
NE2
|
E:GLN136
|
4.3
|
132.8
|
1.0
|
|
CG
|
E:GLU105
|
4.5
|
129.3
|
1.0
|
|
OG
|
E:SER102
|
4.6
|
129.8
|
1.0
|
|
CA
|
E:TYR100
|
4.6
|
130.1
|
1.0
|
|
N
|
E:ASP96
|
4.6
|
130.0
|
1.0
|
|
N
|
E:TYR100
|
4.7
|
130.5
|
1.0
|
|
CB
|
E:SER102
|
4.8
|
134.4
|
1.0
|
|
CA
|
E:ASP94
|
4.8
|
115.6
|
1.0
|
|
CA
|
E:ASP96
|
4.9
|
131.5
|
1.0
|
|
CB
|
E:ASP94
|
4.9
|
116.5
|
1.0
|
|
CA
|
E:SER102
|
4.9
|
134.3
|
1.0
|
|
CB
|
E:ILE101
|
5.0
|
127.1
|
1.0
|
|
CG2
|
E:ILE101
|
5.0
|
122.9
|
1.0
|
|
Calcium binding site 4 out
of 16 in 9o52
Go back to
Calcium Binding Sites List in 9o52
Calcium binding site 4 out
of 16 in the Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca504
b:151.1
occ:1.00
|
OD1
|
E:ASP134
|
2.3
|
150.8
|
1.0
|
|
OE2
|
E:GLU141
|
2.3
|
148.4
|
1.0
|
|
OD2
|
E:ASP134
|
2.7
|
148.4
|
1.0
|
|
CG
|
E:ASP134
|
2.8
|
150.3
|
1.0
|
|
CD
|
E:GLU141
|
2.8
|
145.2
|
1.0
|
|
OD1
|
E:ASP132
|
2.9
|
153.8
|
1.0
|
|
O
|
E:GLN136
|
2.9
|
146.7
|
1.0
|
|
OE1
|
E:GLU141
|
3.2
|
143.6
|
1.0
|
|
OD2
|
E:ASP132
|
3.2
|
154.3
|
1.0
|
|
OD1
|
E:ASP130
|
3.3
|
150.2
|
1.0
|
|
CG
|
E:ASP132
|
3.4
|
154.0
|
1.0
|
|
C
|
E:GLN136
|
3.8
|
144.8
|
1.0
|
|
CG
|
E:GLU141
|
3.8
|
138.9
|
1.0
|
|
N
|
E:ASN138
|
4.0
|
128.6
|
1.0
|
|
CB
|
E:ASP134
|
4.1
|
151.3
|
1.0
|
|
CA
|
E:VAL137
|
4.2
|
135.6
|
1.0
|
|
CB
|
E:ASN138
|
4.3
|
131.7
|
1.0
|
|
N
|
E:VAL137
|
4.3
|
141.1
|
1.0
|
|
CG
|
E:ASP130
|
4.3
|
150.2
|
1.0
|
|
C
|
E:VAL137
|
4.4
|
129.8
|
1.0
|
|
N
|
E:ASP134
|
4.7
|
153.7
|
1.0
|
|
N
|
E:GLN136
|
4.7
|
147.3
|
1.0
|
|
CE2
|
E:TYR100
|
4.8
|
134.3
|
1.0
|
|
CA
|
E:GLN136
|
4.8
|
144.8
|
1.0
|
|
CA
|
E:ASN138
|
4.8
|
129.7
|
1.0
|
|
OD2
|
E:ASP130
|
4.9
|
151.4
|
1.0
|
|
CA
|
E:ASP134
|
4.9
|
152.7
|
1.0
|
|
OE2
|
E:GLU140
|
4.9
|
133.2
|
1.0
|
|
CB
|
E:ASP132
|
4.9
|
153.2
|
1.0
|
|
Calcium binding site 5 out
of 16 in 9o52
Go back to
Calcium Binding Sites List in 9o52
Calcium binding site 5 out
of 16 in the Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Ca501
b:98.9
occ:1.00
|
OD1
|
F:ASP21
|
2.3
|
87.9
|
1.0
|
|
OD1
|
F:ASP23
|
2.3
|
95.9
|
1.0
|
|
OE1
|
F:GLU32
|
2.3
|
92.4
|
1.0
|
|
O
|
F:THR27
|
2.4
|
91.1
|
1.0
|
|
OD1
|
F:ASP25
|
2.4
|
98.2
|
1.0
|
|
OD2
|
F:ASP23
|
2.8
|
96.4
|
1.0
|
|
OE2
|
F:GLU32
|
2.8
|
92.3
|
1.0
|
|
CD
|
F:GLU32
|
2.8
|
92.4
|
1.0
|
|
CG
|
F:ASP23
|
2.9
|
94.4
|
1.0
|
|
CG
|
F:ASP25
|
3.2
|
98.9
|
1.0
|
|
CG
|
F:ASP21
|
3.4
|
88.0
|
1.0
|
|
OD2
|
F:ASP25
|
3.5
|
100.7
|
1.0
|
|
OG1
|
F:THR29
|
3.6
|
99.8
|
1.0
|
|
C
|
F:THR27
|
3.6
|
91.0
|
1.0
|
|
OD2
|
F:ASP21
|
3.9
|
90.6
|
1.0
|
|
N
|
F:THR29
|
4.0
|
93.9
|
1.0
|
|
CG
|
F:GLU32
|
4.2
|
91.4
|
1.0
|
|
CB
|
F:ASP23
|
4.4
|
92.6
|
1.0
|
|
CA
|
F:ILE28
|
4.4
|
86.3
|
1.0
|
|
CB
|
F:ASP25
|
4.4
|
97.5
|
1.0
|
|
N
|
F:ILE28
|
4.4
|
89.4
|
1.0
|
|
N
|
F:THR27
|
4.5
|
91.2
|
1.0
|
|
OG1
|
F:THR27
|
4.5
|
94.3
|
1.0
|
|
CB
|
F:THR29
|
4.5
|
97.8
|
1.0
|
|
N
|
F:ASP25
|
4.6
|
94.9
|
1.0
|
|
CA
|
F:THR27
|
4.6
|
91.3
|
1.0
|
|
CB
|
F:ASP21
|
4.7
|
82.8
|
1.0
|
|
C
|
F:ILE28
|
4.7
|
91.4
|
1.0
|
|
N
|
F:ASP23
|
4.7
|
96.6
|
1.0
|
|
CA
|
F:ASP21
|
4.8
|
84.2
|
1.0
|
|
CA
|
F:THR29
|
4.9
|
94.9
|
1.0
|
|
N
|
F:GLY24
|
4.9
|
94.9
|
1.0
|
|
CA
|
F:ASP25
|
5.0
|
96.2
|
1.0
|
|
Calcium binding site 6 out
of 16 in 9o52
Go back to
Calcium Binding Sites List in 9o52
Calcium binding site 6 out
of 16 in the Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 6 of Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Ca502
b:107.9
occ:1.00
|
OD1
|
F:ASN61
|
2.3
|
109.0
|
1.0
|
|
OD1
|
F:ASP59
|
2.3
|
111.4
|
1.0
|
|
OE2
|
F:GLU68
|
2.4
|
105.5
|
1.0
|
|
OE1
|
F:GLU68
|
2.4
|
98.6
|
1.0
|
|
OD1
|
F:ASP57
|
2.4
|
102.1
|
1.0
|
|
O
|
F:THR63
|
2.5
|
102.2
|
1.0
|
|
CD
|
F:GLU68
|
2.7
|
100.7
|
1.0
|
|
CG
|
F:ASN61
|
2.9
|
107.8
|
1.0
|
|
ND2
|
F:ASN61
|
3.0
|
105.2
|
1.0
|
|
OD2
|
F:ASP59
|
3.0
|
107.8
|
1.0
|
|
CG
|
F:ASP59
|
3.0
|
111.6
|
1.0
|
|
CG
|
F:ASP57
|
3.6
|
104.2
|
1.0
|
|
C
|
F:THR63
|
3.7
|
99.3
|
1.0
|
|
OD1
|
F:ASP65
|
4.1
|
97.4
|
1.0
|
|
OD2
|
F:ASP57
|
4.1
|
105.8
|
1.0
|
|
CG
|
F:GLU68
|
4.2
|
95.0
|
1.0
|
|
CG
|
F:ASP65
|
4.3
|
98.5
|
1.0
|
|
CB
|
F:ASN61
|
4.3
|
106.0
|
1.0
|
|
N
|
F:ASP65
|
4.3
|
89.8
|
1.0
|
|
N
|
F:ASN61
|
4.5
|
108.2
|
1.0
|
|
OD2
|
F:ASP65
|
4.5
|
103.7
|
1.0
|
|
N
|
F:THR63
|
4.5
|
104.9
|
1.0
|
|
CB
|
F:ASP59
|
4.5
|
112.0
|
1.0
|
|
CA
|
F:ILE64
|
4.5
|
91.4
|
1.0
|
|
N
|
F:ILE64
|
4.5
|
94.7
|
1.0
|
|
OG1
|
F:THR63
|
4.6
|
100.5
|
1.0
|
|
N
|
F:ASP59
|
4.7
|
108.9
|
1.0
|
|
CA
|
F:THR63
|
4.7
|
100.5
|
1.0
|
|
CB
|
F:ASP57
|
4.8
|
107.5
|
1.0
|
|
CA
|
F:ASP57
|
4.8
|
109.2
|
1.0
|
|
CA
|
F:ASN61
|
4.9
|
107.0
|
1.0
|
|
N
|
F:GLY60
|
4.9
|
110.2
|
1.0
|
|
C
|
F:ILE64
|
4.9
|
88.8
|
1.0
|
|
CB
|
F:ASP65
|
4.9
|
92.9
|
1.0
|
|
CB
|
F:GLU68
|
5.0
|
89.0
|
1.0
|
|
Calcium binding site 7 out
of 16 in 9o52
Go back to
Calcium Binding Sites List in 9o52
Calcium binding site 7 out
of 16 in the Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 7 of Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Ca503
b:139.2
occ:1.00
|
OE1
|
F:GLU105
|
2.3
|
128.5
|
1.0
|
|
O
|
F:TYR100
|
2.3
|
134.4
|
1.0
|
|
OD1
|
F:ASP96
|
2.4
|
127.3
|
1.0
|
|
OD2
|
F:ASP96
|
2.4
|
131.1
|
1.0
|
|
CG
|
F:ASP96
|
2.6
|
129.7
|
1.0
|
|
OD1
|
F:ASP94
|
2.7
|
122.6
|
1.0
|
|
OD1
|
F:ASN98
|
3.0
|
132.3
|
1.0
|
|
CD
|
F:GLU105
|
3.0
|
126.6
|
1.0
|
|
OE2
|
F:GLU105
|
3.1
|
123.8
|
1.0
|
|
C
|
F:TYR100
|
3.4
|
132.5
|
1.0
|
|
CG
|
F:ASP94
|
3.7
|
121.7
|
1.0
|
|
CA
|
F:ILE101
|
3.8
|
130.2
|
1.0
|
|
N
|
F:SER102
|
3.9
|
131.0
|
1.0
|
|
CG
|
F:ASN98
|
3.9
|
130.7
|
1.0
|
|
CB
|
F:ASP96
|
4.0
|
129.8
|
1.0
|
|
N
|
F:ILE101
|
4.0
|
130.4
|
1.0
|
|
OD2
|
F:ASP94
|
4.1
|
126.0
|
1.0
|
|
C
|
F:ILE101
|
4.3
|
131.6
|
1.0
|
|
ND2
|
F:ASN98
|
4.3
|
128.2
|
1.0
|
|
NE2
|
F:GLN136
|
4.4
|
134.3
|
1.0
|
|
CG
|
F:GLU105
|
4.5
|
125.1
|
1.0
|
|
N
|
F:ASP96
|
4.6
|
126.4
|
1.0
|
|
CA
|
F:TYR100
|
4.6
|
132.6
|
1.0
|
|
OG
|
F:SER102
|
4.6
|
131.5
|
1.0
|
|
N
|
F:TYR100
|
4.7
|
131.4
|
1.0
|
|
CA
|
F:ASP94
|
4.8
|
108.0
|
1.0
|
|
CB
|
F:SER102
|
4.8
|
133.5
|
1.0
|
|
CB
|
F:ASP94
|
4.8
|
111.0
|
1.0
|
|
CA
|
F:ASP96
|
4.9
|
128.3
|
1.0
|
|
CG2
|
F:ILE101
|
4.9
|
117.7
|
1.0
|
|
CA
|
F:SER102
|
4.9
|
130.7
|
1.0
|
|
CB
|
F:ILE101
|
5.0
|
125.6
|
1.0
|
|
Calcium binding site 8 out
of 16 in 9o52
Go back to
Calcium Binding Sites List in 9o52
Calcium binding site 8 out
of 16 in the Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 8 of Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Ca504
b:154.2
occ:1.00
|
OD1
|
F:ASP134
|
2.2
|
154.7
|
1.0
|
|
OE2
|
F:GLU141
|
2.4
|
153.0
|
1.0
|
|
O
|
F:GLN136
|
2.4
|
148.8
|
1.0
|
|
CD
|
F:GLU141
|
2.7
|
149.2
|
1.0
|
|
OE1
|
F:GLU141
|
2.8
|
147.8
|
1.0
|
|
CG
|
F:ASP134
|
2.9
|
154.7
|
1.0
|
|
OD1
|
F:ASP130
|
3.0
|
153.2
|
1.0
|
|
OD1
|
F:ASP132
|
3.0
|
157.0
|
1.0
|
|
OD2
|
F:ASP134
|
3.0
|
151.0
|
1.0
|
|
C
|
F:GLN136
|
3.4
|
148.4
|
1.0
|
|
OD2
|
F:ASP132
|
3.6
|
157.4
|
1.0
|
|
CG
|
F:ASP132
|
3.7
|
156.9
|
1.0
|
|
CG
|
F:GLU141
|
3.8
|
139.3
|
1.0
|
|
CA
|
F:VAL137
|
3.9
|
140.4
|
1.0
|
|
N
|
F:ASN138
|
4.0
|
133.2
|
1.0
|
|
N
|
F:VAL137
|
4.0
|
144.8
|
1.0
|
|
CG
|
F:ASP130
|
4.0
|
153.5
|
1.0
|
|
CB
|
F:ASP134
|
4.2
|
155.2
|
1.0
|
|
C
|
F:VAL137
|
4.2
|
135.5
|
1.0
|
|
N
|
F:GLN136
|
4.4
|
152.2
|
1.0
|
|
CA
|
F:GLN136
|
4.5
|
148.3
|
1.0
|
|
CB
|
F:ASN138
|
4.5
|
134.2
|
1.0
|
|
OD2
|
F:ASP130
|
4.6
|
154.1
|
1.0
|
|
N
|
F:ASP134
|
4.6
|
156.7
|
1.0
|
|
CA
|
F:ASP130
|
4.8
|
151.1
|
1.0
|
|
CB
|
F:GLU141
|
4.9
|
134.1
|
1.0
|
|
CA
|
F:ASN138
|
4.9
|
130.5
|
1.0
|
|
CA
|
F:ASP134
|
4.9
|
155.1
|
1.0
|
|
CB
|
F:ASP130
|
5.0
|
151.5
|
1.0
|
|
Calcium binding site 9 out
of 16 in 9o52
Go back to
Calcium Binding Sites List in 9o52
Calcium binding site 9 out
of 16 in the Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 9 of Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Ca501
b:98.1
occ:1.00
|
OE1
|
G:GLU32
|
2.3
|
104.8
|
1.0
|
|
OD1
|
G:ASP23
|
2.3
|
100.3
|
1.0
|
|
OD1
|
G:ASP25
|
2.3
|
102.4
|
1.0
|
|
O
|
G:THR27
|
2.4
|
97.3
|
1.0
|
|
OD1
|
G:ASP21
|
2.5
|
94.4
|
1.0
|
|
OE2
|
G:GLU32
|
2.7
|
103.0
|
1.0
|
|
CD
|
G:GLU32
|
2.7
|
104.9
|
1.0
|
|
OD2
|
G:ASP23
|
2.7
|
103.3
|
1.0
|
|
CG
|
G:ASP23
|
2.9
|
101.9
|
1.0
|
|
CG
|
G:ASP25
|
3.2
|
101.4
|
1.0
|
|
OD2
|
G:ASP25
|
3.5
|
101.0
|
1.0
|
|
CG
|
G:ASP21
|
3.6
|
94.8
|
1.0
|
|
OG1
|
G:THR29
|
3.6
|
104.5
|
1.0
|
|
C
|
G:THR27
|
3.7
|
94.1
|
1.0
|
|
N
|
G:THR29
|
4.1
|
99.6
|
1.0
|
|
CG
|
G:GLU32
|
4.1
|
100.3
|
1.0
|
|
OD2
|
G:ASP21
|
4.1
|
94.5
|
1.0
|
|
CB
|
G:ASP25
|
4.3
|
100.7
|
1.0
|
|
CB
|
G:ASP23
|
4.4
|
98.2
|
1.0
|
|
CA
|
G:ILE28
|
4.5
|
95.4
|
1.0
|
|
N
|
G:THR27
|
4.5
|
95.5
|
1.0
|
|
N
|
G:ASP25
|
4.5
|
101.6
|
1.0
|
|
N
|
G:ILE28
|
4.5
|
91.9
|
1.0
|
|
OG1
|
G:THR27
|
4.6
|
101.2
|
1.0
|
|
CB
|
G:THR29
|
4.6
|
103.5
|
1.0
|
|
CA
|
G:THR27
|
4.7
|
95.6
|
1.0
|
|
N
|
G:ASP23
|
4.7
|
101.3
|
1.0
|
|
C
|
G:ILE28
|
4.8
|
98.3
|
1.0
|
|
CB
|
G:ASP21
|
4.8
|
91.2
|
1.0
|
|
CA
|
G:ASP21
|
4.9
|
91.5
|
1.0
|
|
N
|
G:GLY24
|
4.9
|
98.3
|
1.0
|
|
CA
|
G:ASP25
|
4.9
|
100.9
|
1.0
|
|
CA
|
G:ASP23
|
5.0
|
97.6
|
1.0
|
|
CA
|
G:THR29
|
5.0
|
99.8
|
1.0
|
|
Calcium binding site 10 out
of 16 in 9o52
Go back to
Calcium Binding Sites List in 9o52
Calcium binding site 10 out
of 16 in the Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 10 of Cryo-Em Structure of the Human SK2-4 Chimera/Calmodulin Channel Complex Bound to the Bee Toxin Apamin within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Ca502
b:102.4
occ:1.00
|
OD1
|
G:ASP59
|
2.3
|
116.2
|
1.0
|
|
O
|
G:THR63
|
2.3
|
102.0
|
1.0
|
|
OD1
|
G:ASP57
|
2.4
|
105.5
|
1.0
|
|
OE1
|
G:GLU68
|
2.4
|
104.1
|
1.0
|
|
OD1
|
G:ASN61
|
2.4
|
109.8
|
1.0
|
|
OE2
|
G:GLU68
|
2.5
|
107.5
|
1.0
|
|
CD
|
G:GLU68
|
2.8
|
104.4
|
1.0
|
|
OD2
|
G:ASP59
|
3.0
|
114.3
|
1.0
|
|
CG
|
G:ASP59
|
3.0
|
117.4
|
1.0
|
|
CG
|
G:ASN61
|
3.1
|
109.1
|
1.0
|
|
ND2
|
G:ASN61
|
3.2
|
111.2
|
1.0
|
|
C
|
G:THR63
|
3.6
|
101.0
|
1.0
|
|
CG
|
G:ASP57
|
3.6
|
106.9
|
1.0
|
|
N
|
G:ASP65
|
4.1
|
90.4
|
1.0
|
|
OD2
|
G:ASP57
|
4.2
|
107.5
|
1.0
|
|
OD1
|
G:ASP65
|
4.2
|
97.0
|
1.0
|
|
CG
|
G:GLU68
|
4.3
|
99.1
|
1.0
|
|
CA
|
G:ILE64
|
4.3
|
94.5
|
1.0
|
|
N
|
G:ILE64
|
4.4
|
98.3
|
1.0
|
|
CG
|
G:ASP65
|
4.4
|
100.0
|
1.0
|
|
N
|
G:THR63
|
4.4
|
105.8
|
1.0
|
|
CB
|
G:ASN61
|
4.5
|
106.8
|
1.0
|
|
CB
|
G:ASP59
|
4.5
|
118.0
|
1.0
|
|
N
|
G:ASN61
|
4.6
|
108.7
|
1.0
|
|
CA
|
G:THR63
|
4.6
|
102.7
|
1.0
|
|
OG1
|
G:THR63
|
4.6
|
101.1
|
1.0
|
|
N
|
G:ASP59
|
4.6
|
109.3
|
1.0
|
|
C
|
G:ILE64
|
4.7
|
91.6
|
1.0
|
|
CB
|
G:ASP57
|
4.7
|
109.6
|
1.0
|
|
CA
|
G:ASP57
|
4.8
|
108.5
|
1.0
|
|
OD2
|
G:ASP65
|
4.8
|
101.8
|
1.0
|
|
CB
|
G:ASP65
|
4.8
|
96.0
|
1.0
|
|
N
|
G:GLY60
|
4.9
|
110.2
|
1.0
|
|
N
|
G:ALA58
|
4.9
|
109.7
|
1.0
|
|
Reference:
S.J.Cassell,
W.Li,
S.Krautwald,
M.Khoshouei,
Y.T.Lee,
J.Hou,
W.Guan,
S.Peukert,
W.A.Wilhelm,
J.R.Whicher.
Mechanism of SK2 Channel Gating and Its Modulation By the Bee Toxin Apamin and Small Molecules To Be Published.
Page generated: Mon Aug 4 19:00:41 2025
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