Calcium in PDB 9ven: Structure of Human KCNQ1-Cam-PIP2 Complex with Bent Conformation

The binding sites of Calcium atom in the Structure of Human KCNQ1-Cam-PIP2 Complex with Bent Conformation (pdb code 9ven). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 8 binding sites of Calcium where determined in the Structure of Human KCNQ1-Cam-PIP2 Complex with Bent Conformation, PDB code: 9ven:
Jump to Calcium binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Calcium binding site 1 out of 8 in the Structure of Human KCNQ1-Cam-PIP2 Complex with Bent Conformation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of Human KCNQ1-Cam-PIP2 Complex with Bent Conformation within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca201 b:56.1 occ:1.00 OD2 B:ASP23 1.7 51.5 1.0 OD1 B:ASP23 2.1 51.5 1.0 OD2 B:ASP25 2.1 48.8 1.0 CG B:ASP23 2.1 51.5 1.0 OD1 B:ASP25 2.6 48.8 1.0 CG B:ASP25 2.6 48.8 1.0 O B:THR27 3.1 42.3 1.0 CB B:ASP23 3.6 51.5 1.0 CB B:ASP25 4.0 48.8 1.0 C B:THR27 4.1 42.3 1.0 O B:ASP23 4.1 51.5 1.0 CB B:ASP21 4.2 41.2 1.0 CA B:ILE28 4.4 37.6 1.0 CA B:ASP23 4.5 51.5 1.0 C B:ASP23 4.5 51.5 1.0 N B:ILE28 4.6 37.6 1.0 CA B:ASP21 4.7 41.2 1.0 CG2 B:THR27 4.7 42.3 1.0 N B:ASP23 4.7 51.5 1.0 N B:THR29 4.8 40.6 1.0 CB B:GLU32 4.8 38.0 1.0 OG1 B:THR29 4.9 40.6 1.0

Calcium binding site 2 out of 8 in the Structure of Human KCNQ1-Cam-PIP2 Complex with Bent Conformation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of Human KCNQ1-Cam-PIP2 Complex with Bent Conformation within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca202 b:44.9 occ:0.91 O B:THR63 2.5 37.3 1.0 CB B:ASN61 3.0 32.8 1.0 ND2 B:ASN61 3.6 32.8 1.0 C B:THR63 3.7 37.3 1.0 CG B:ASN61 3.8 32.8 1.0 CB B:ASP59 3.8 33.5 1.0 OD2 B:ASP57 3.9 36.0 1.0 CB B:ASP57 4.1 36.0 1.0 CA B:ASN61 4.1 32.8 1.0 OG1 B:THR63 4.2 37.3 1.0 N B:ASN61 4.2 32.8 1.0 N B:THR63 4.4 37.3 1.0 CG B:ASP57 4.5 36.0 1.0 N B:ASP65 4.5 36.8 1.0 CA B:THR63 4.6 37.3 1.0 N B:ILE64 4.6 35.4 1.0 C B:ASN61 4.6 32.8 1.0 CA B:ILE64 4.7 35.4 1.0 N B:GLY62 4.8 34.8 1.0 CA B:ASP59 4.8 33.5 1.0 C B:ILE64 4.9 35.4 1.0 N B:ASP59 4.9 33.5 1.0 CB B:ASP65 5.0 36.8 1.0

Calcium binding site 3 out of 8 in the Structure of Human KCNQ1-Cam-PIP2 Complex with Bent Conformation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Structure of Human KCNQ1-Cam-PIP2 Complex with Bent Conformation within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca201 b:56.1 occ:1.00 OD2 D:ASP23 1.7 51.5 1.0 OD1 D:ASP23 2.1 51.5 1.0 OD2 D:ASP25 2.1 48.8 1.0 CG D:ASP23 2.1 51.5 1.0 OD1 D:ASP25 2.6 48.8 1.0 CG D:ASP25 2.6 48.8 1.0 O D:THR27 3.1 42.3 1.0 CB D:ASP23 3.6 51.5 1.0 CB D:ASP25 4.0 48.8 1.0 C D:THR27 4.1 42.3 1.0 O D:ASP23 4.1 51.5 1.0 CB D:ASP21 4.2 41.2 1.0 CA D:ILE28 4.4 37.6 1.0 CA D:ASP23 4.5 51.5 1.0 C D:ASP23 4.5 51.5 1.0 N D:ILE28 4.6 37.6 1.0 CA D:ASP21 4.7 41.2 1.0 CG2 D:THR27 4.7 42.3 1.0 N D:ASP23 4.7 51.5 1.0 N D:THR29 4.8 40.6 1.0 CB D:GLU32 4.8 38.0 1.0 OG1 D:THR29 4.9 40.6 1.0

Calcium binding site 4 out of 8 in the Structure of Human KCNQ1-Cam-PIP2 Complex with Bent Conformation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Structure of Human KCNQ1-Cam-PIP2 Complex with Bent Conformation within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca202 b:44.9 occ:0.91 O D:THR63 2.5 37.3 1.0 CB D:ASN61 3.0 32.8 1.0 ND2 D:ASN61 3.6 32.8 1.0 C D:THR63 3.7 37.3 1.0 CG D:ASN61 3.8 32.8 1.0 CB D:ASP59 3.8 33.5 1.0 OD2 D:ASP57 3.9 36.0 1.0 CB D:ASP57 4.1 36.0 1.0 CA D:ASN61 4.1 32.8 1.0 OG1 D:THR63 4.2 37.3 1.0 N D:ASN61 4.2 32.8 1.0 N D:THR63 4.4 37.3 1.0 CG D:ASP57 4.5 36.0 1.0 N D:ASP65 4.5 36.8 1.0 CA D:THR63 4.6 37.3 1.0 N D:ILE64 4.6 35.4 1.0 C D:ASN61 4.6 32.8 1.0 CA D:ILE64 4.7 35.4 1.0 N D:GLY62 4.8 34.8 1.0 CA D:ASP59 4.8 33.5 1.0 C D:ILE64 4.9 35.4 1.0 N D:ASP59 4.9 33.5 1.0 CB D:ASP65 5.0 36.8 1.0

Calcium binding site 5 out of 8 in the Structure of Human KCNQ1-Cam-PIP2 Complex with Bent Conformation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Structure of Human KCNQ1-Cam-PIP2 Complex with Bent Conformation within 5.0Å range: probe atom residue distance (Å) B Occ F:Ca201 b:56.1 occ:1.00 OD2 F:ASP23 1.7 51.5 1.0 OD1 F:ASP23 2.1 51.5 1.0 OD2 F:ASP25 2.1 48.8 1.0 CG F:ASP23 2.1 51.5 1.0 OD1 F:ASP25 2.6 48.8 1.0 CG F:ASP25 2.6 48.8 1.0 O F:THR27 3.1 42.3 1.0 CB F:ASP23 3.6 51.5 1.0 CB F:ASP25 4.0 48.8 1.0 C F:THR27 4.1 42.3 1.0 O F:ASP23 4.1 51.5 1.0 CB F:ASP21 4.2 41.2 1.0 CA F:ILE28 4.4 37.6 1.0 CA F:ASP23 4.5 51.5 1.0 C F:ASP23 4.5 51.5 1.0 N F:ILE28 4.6 37.6 1.0 CA F:ASP21 4.7 41.2 1.0 CG2 F:THR27 4.7 42.3 1.0 N F:ASP23 4.7 51.5 1.0 N F:THR29 4.8 40.6 1.0 CB F:GLU32 4.8 38.0 1.0 OG1 F:THR29 4.9 40.6 1.0

Calcium binding site 6 out of 8 in the Structure of Human KCNQ1-Cam-PIP2 Complex with Bent Conformation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 6 of Structure of Human KCNQ1-Cam-PIP2 Complex with Bent Conformation within 5.0Å range: probe atom residue distance (Å) B Occ F:Ca202 b:44.9 occ:0.91 O F:THR63 2.5 37.3 1.0 CB F:ASN61 3.0 32.8 1.0 ND2 F:ASN61 3.6 32.8 1.0 C F:THR63 3.7 37.3 1.0 CB F:ASP59 3.8 33.5 1.0 CG F:ASN61 3.8 32.8 1.0 OD2 F:ASP57 3.9 36.0 1.0 CB F:ASP57 4.1 36.0 1.0 CA F:ASN61 4.1 32.8 1.0 OG1 F:THR63 4.2 37.3 1.0 N F:ASN61 4.2 32.8 1.0 N F:THR63 4.4 37.3 1.0 CG F:ASP57 4.5 36.0 1.0 N F:ASP65 4.5 36.8 1.0 CA F:THR63 4.6 37.3 1.0 N F:ILE64 4.6 35.4 1.0 C F:ASN61 4.6 32.8 1.0 CA F:ILE64 4.7 35.4 1.0 N F:GLY62 4.8 34.8 1.0 CA F:ASP59 4.8 33.5 1.0 C F:ILE64 4.9 35.4 1.0 N F:ASP59 4.9 33.5 1.0 CB F:ASP65 5.0 36.8 1.0

Calcium binding site 7 out of 8 in the Structure of Human KCNQ1-Cam-PIP2 Complex with Bent Conformation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 7 of Structure of Human KCNQ1-Cam-PIP2 Complex with Bent Conformation within 5.0Å range: probe atom residue distance (Å) B Occ H:Ca201 b:56.1 occ:1.00 OD2 H:ASP23 1.7 51.5 1.0 OD1 H:ASP23 2.1 51.5 1.0 OD2 H:ASP25 2.1 48.8 1.0 CG H:ASP23 2.1 51.5 1.0 OD1 H:ASP25 2.6 48.8 1.0 CG H:ASP25 2.6 48.8 1.0 O H:THR27 3.1 42.3 1.0 CB H:ASP23 3.6 51.5 1.0 CB H:ASP25 4.0 48.8 1.0 C H:THR27 4.1 42.3 1.0 O H:ASP23 4.1 51.5 1.0 CB H:ASP21 4.2 41.2 1.0 CA H:ILE28 4.4 37.6 1.0 CA H:ASP23 4.5 51.5 1.0 C H:ASP23 4.5 51.5 1.0 N H:ILE28 4.6 37.6 1.0 CA H:ASP21 4.7 41.2 1.0 CG2 H:THR27 4.7 42.3 1.0 N H:ASP23 4.7 51.5 1.0 N H:THR29 4.8 40.6 1.0 CB H:GLU32 4.8 38.0 1.0 OG1 H:THR29 4.9 40.6 1.0

Calcium binding site 8 out of 8 in the Structure of Human KCNQ1-Cam-PIP2 Complex with Bent Conformation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 8 of Structure of Human KCNQ1-Cam-PIP2 Complex with Bent Conformation within 5.0Å range: probe atom residue distance (Å) B Occ H:Ca202 b:44.9 occ:0.91 O H:THR63 2.5 37.3 1.0 CB H:ASN61 3.0 32.8 1.0 ND2 H:ASN61 3.6 32.8 1.0 C H:THR63 3.7 37.3 1.0 CG H:ASN61 3.8 32.8 1.0 CB H:ASP59 3.8 33.5 1.0 OD2 H:ASP57 3.9 36.0 1.0 CB H:ASP57 4.1 36.0 1.0 CA H:ASN61 4.1 32.8 1.0 OG1 H:THR63 4.2 37.3 1.0 N H:ASN61 4.2 32.8 1.0 N H:THR63 4.4 37.3 1.0 CG H:ASP57 4.5 36.0 1.0 N H:ASP65 4.5 36.8 1.0 CA H:THR63 4.6 37.3 1.0 N H:ILE64 4.6 35.4 1.0 C H:ASN61 4.6 32.8 1.0 CA H:ILE64 4.7 35.4 1.0 N H:GLY62 4.8 34.8 1.0 CA H:ASP59 4.8 33.5 1.0 C H:ILE64 4.9 35.4 1.0 N H:ASP59 4.9 33.5 1.0 CB H:ASP65 5.0 36.8 1.0

C.Cui, L.Zhao, A.A.Kermani, S.Du, T.Pipatpolkai, M.Jiang, S.Chittori, Y.Z.Tan, J.Shi, L.Delemotte, J.Cui, J.Sun. Mechanisms of KCNQ1 Gating Modulation By KCNE1/3 For Cell-Specific Function. Cell Res. 2025.
ISSN: ISSN 1001-0602
PubMed: 40745202
DOI: 10.1038/S41422-025-01152-1