Calcium in PDB 9veo: Structure of Human KCNQ1-Cam-PIP2 Complex with Straight Conformation

The binding sites of Calcium atom in the Structure of Human KCNQ1-Cam-PIP2 Complex with Straight Conformation (pdb code 9veo). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 8 binding sites of Calcium where determined in the Structure of Human KCNQ1-Cam-PIP2 Complex with Straight Conformation, PDB code: 9veo:
Jump to Calcium binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Calcium binding site 1 out of 8 in the Structure of Human KCNQ1-Cam-PIP2 Complex with Straight Conformation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of Human KCNQ1-Cam-PIP2 Complex with Straight Conformation within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca201 b:0.0 occ:1.00 CB B:THR27 3.0 0.0 1.0 CB B:ASP21 3.6 0.0 1.0 CB B:THR29 3.9 0.0 1.0 O B:ASP21 4.0 0.0 1.0 O B:ASP25 4.0 0.0 1.0 CA B:THR27 4.0 0.0 1.0 CB B:ASP23 4.0 0.0 1.0 O B:THR27 4.1 0.0 1.0 N B:THR27 4.2 0.0 1.0 C B:THR27 4.3 0.0 1.0 CB B:ASP25 4.3 0.0 1.0 CA B:ASP21 4.6 0.0 1.0 C B:ASP21 4.6 0.0 1.0 C B:ASP25 4.6 0.0 1.0 CA B:ASP25 4.9 0.0 1.0 CA B:THR29 4.9 0.0 1.0 O B:ASP23 4.9 0.0 1.0

Calcium binding site 2 out of 8 in the Structure of Human KCNQ1-Cam-PIP2 Complex with Straight Conformation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of Human KCNQ1-Cam-PIP2 Complex with Straight Conformation within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca202 b:0.0 occ:0.65 CB B:ILE64 3.0 0.0 1.0 CB B:ASN61 3.1 0.0 1.0 N B:ASN61 3.3 0.0 1.0 N B:ILE64 3.4 0.0 1.0 CB B:ASP57 3.4 0.0 1.0 N B:GLY62 3.4 0.0 1.0 CA B:ASN61 3.5 0.0 1.0 N B:THR63 3.6 0.0 1.0 C B:THR63 3.7 0.0 1.0 C B:ASN61 3.7 0.0 1.0 CA B:ILE64 3.8 0.0 1.0 CG B:PRO67 4.0 0.0 1.0 CA B:THR63 4.1 0.0 1.0 O B:THR63 4.2 0.0 1.0 C B:GLY62 4.2 0.0 1.0 CA B:ASP57 4.3 0.0 1.0 CA B:GLY62 4.4 0.0 1.0 C B:GLY60 4.4 0.0 1.0 N B:GLY60 4.6 0.0 1.0 O B:ASN61 4.6 0.0 1.0 CD B:PRO67 4.7 0.0 1.0 CB B:PRO67 4.7 0.0 1.0 CA B:GLY60 4.9 0.0 1.0 C B:ILE64 5.0 0.0 1.0 C B:ASP57 5.0 0.0 1.0

Calcium binding site 3 out of 8 in the Structure of Human KCNQ1-Cam-PIP2 Complex with Straight Conformation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Structure of Human KCNQ1-Cam-PIP2 Complex with Straight Conformation within 5.0Å range: probe atom residue distance (Å) B Occ H:Ca201 b:0.0 occ:1.00 CB H:THR27 3.0 0.0 1.0 CB H:ASP21 3.6 0.0 1.0 CB H:THR29 3.9 0.0 1.0 O H:ASP21 4.0 0.0 1.0 O H:ASP25 4.0 0.0 1.0 CA H:THR27 4.0 0.0 1.0 CB H:ASP23 4.0 0.0 1.0 O H:THR27 4.1 0.0 1.0 N H:THR27 4.2 0.0 1.0 C H:THR27 4.3 0.0 1.0 CB H:ASP25 4.3 0.0 1.0 CA H:ASP21 4.6 0.0 1.0 C H:ASP21 4.6 0.0 1.0 C H:ASP25 4.6 0.0 1.0 CA H:ASP25 4.9 0.0 1.0 CA H:THR29 4.9 0.0 1.0 O H:ASP23 4.9 0.0 1.0

Calcium binding site 4 out of 8 in the Structure of Human KCNQ1-Cam-PIP2 Complex with Straight Conformation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Structure of Human KCNQ1-Cam-PIP2 Complex with Straight Conformation within 5.0Å range: probe atom residue distance (Å) B Occ H:Ca202 b:0.0 occ:0.65 CB H:ILE64 3.0 0.0 1.0 CB H:ASN61 3.1 0.0 1.0 N H:ASN61 3.3 0.0 1.0 N H:ILE64 3.4 0.0 1.0 CB H:ASP57 3.4 0.0 1.0 N H:GLY62 3.4 0.0 1.0 CA H:ASN61 3.5 0.0 1.0 N H:THR63 3.6 0.0 1.0 C H:THR63 3.7 0.0 1.0 C H:ASN61 3.7 0.0 1.0 CA H:ILE64 3.8 0.0 1.0 CG H:PRO67 4.0 0.0 1.0 CA H:THR63 4.1 0.0 1.0 O H:THR63 4.2 0.0 1.0 C H:GLY62 4.2 0.0 1.0 CA H:ASP57 4.3 0.0 1.0 CA H:GLY62 4.4 0.0 1.0 C H:GLY60 4.4 0.0 1.0 N H:GLY60 4.6 0.0 1.0 O H:ASN61 4.6 0.0 1.0 CD H:PRO67 4.7 0.0 1.0 CB H:PRO67 4.7 0.0 1.0 CA H:GLY60 4.9 0.0 1.0 C H:ILE64 5.0 0.0 1.0 C H:ASP57 5.0 0.0 1.0

Calcium binding site 5 out of 8 in the Structure of Human KCNQ1-Cam-PIP2 Complex with Straight Conformation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of Structure of Human KCNQ1-Cam-PIP2 Complex with Straight Conformation within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca201 b:0.0 occ:1.00 CB D:THR27 3.0 0.0 1.0 CB D:ASP21 3.6 0.0 1.0 CB D:THR29 3.9 0.0 1.0 O D:ASP21 4.0 0.0 1.0 O D:ASP25 4.0 0.0 1.0 CA D:THR27 4.0 0.0 1.0 CB D:ASP23 4.0 0.0 1.0 O D:THR27 4.1 0.0 1.0 N D:THR27 4.2 0.0 1.0 C D:THR27 4.3 0.0 1.0 CB D:ASP25 4.3 0.0 1.0 CA D:ASP21 4.6 0.0 1.0 C D:ASP21 4.6 0.0 1.0 C D:ASP25 4.6 0.0 1.0 CA D:ASP25 4.9 0.0 1.0 CA D:THR29 4.9 0.0 1.0 O D:ASP23 4.9 0.0 1.0

Calcium binding site 6 out of 8 in the Structure of Human KCNQ1-Cam-PIP2 Complex with Straight Conformation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 6 of Structure of Human KCNQ1-Cam-PIP2 Complex with Straight Conformation within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca202 b:0.0 occ:0.65 CB D:ILE64 3.0 0.0 1.0 CB D:ASN61 3.1 0.0 1.0 N D:ASN61 3.3 0.0 1.0 N D:ILE64 3.4 0.0 1.0 CB D:ASP57 3.4 0.0 1.0 N D:GLY62 3.4 0.0 1.0 CA D:ASN61 3.5 0.0 1.0 N D:THR63 3.6 0.0 1.0 C D:THR63 3.7 0.0 1.0 C D:ASN61 3.7 0.0 1.0 CA D:ILE64 3.8 0.0 1.0 CG D:PRO67 4.0 0.0 1.0 CA D:THR63 4.1 0.0 1.0 O D:THR63 4.2 0.0 1.0 C D:GLY62 4.2 0.0 1.0 CA D:ASP57 4.3 0.0 1.0 CA D:GLY62 4.4 0.0 1.0 C D:GLY60 4.4 0.0 1.0 N D:GLY60 4.6 0.0 1.0 O D:ASN61 4.6 0.0 1.0 CD D:PRO67 4.7 0.0 1.0 CB D:PRO67 4.7 0.0 1.0 CA D:GLY60 4.9 0.0 1.0 C D:ILE64 5.0 0.0 1.0 C D:ASP57 5.0 0.0 1.0

Calcium binding site 7 out of 8 in the Structure of Human KCNQ1-Cam-PIP2 Complex with Straight Conformation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 7 of Structure of Human KCNQ1-Cam-PIP2 Complex with Straight Conformation within 5.0Å range: probe atom residue distance (Å) B Occ F:Ca201 b:0.0 occ:1.00 CB F:THR27 3.0 0.0 1.0 CB F:ASP21 3.6 0.0 1.0 CB F:THR29 3.9 0.0 1.0 O F:ASP21 4.0 0.0 1.0 O F:ASP25 4.0 0.0 1.0 CA F:THR27 4.0 0.0 1.0 CB F:ASP23 4.0 0.0 1.0 O F:THR27 4.1 0.0 1.0 N F:THR27 4.2 0.0 1.0 C F:THR27 4.3 0.0 1.0 CB F:ASP25 4.3 0.0 1.0 CA F:ASP21 4.6 0.0 1.0 C F:ASP21 4.6 0.0 1.0 C F:ASP25 4.6 0.0 1.0 CA F:ASP25 4.9 0.0 1.0 CA F:THR29 4.9 0.0 1.0 O F:ASP23 4.9 0.0 1.0

Calcium binding site 8 out of 8 in the Structure of Human KCNQ1-Cam-PIP2 Complex with Straight Conformation


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 8 of Structure of Human KCNQ1-Cam-PIP2 Complex with Straight Conformation within 5.0Å range: probe atom residue distance (Å) B Occ F:Ca202 b:0.0 occ:0.65 CB F:ILE64 3.0 0.0 1.0 CB F:ASN61 3.1 0.0 1.0 N F:ASN61 3.3 0.0 1.0 N F:ILE64 3.4 0.0 1.0 CB F:ASP57 3.4 0.0 1.0 N F:GLY62 3.4 0.0 1.0 CA F:ASN61 3.5 0.0 1.0 N F:THR63 3.6 0.0 1.0 C F:THR63 3.7 0.0 1.0 C F:ASN61 3.7 0.0 1.0 CA F:ILE64 3.8 0.0 1.0 CG F:PRO67 4.0 0.0 1.0 CA F:THR63 4.1 0.0 1.0 O F:THR63 4.2 0.0 1.0 C F:GLY62 4.2 0.0 1.0 CA F:ASP57 4.3 0.0 1.0 CA F:GLY62 4.4 0.0 1.0 C F:GLY60 4.4 0.0 1.0 N F:GLY60 4.6 0.0 1.0 O F:ASN61 4.6 0.0 1.0 CD F:PRO67 4.7 0.0 1.0 CB F:PRO67 4.7 0.0 1.0 CA F:GLY60 4.9 0.0 1.0 C F:ILE64 5.0 0.0 1.0 C F:ASP57 5.0 0.0 1.0

C.Cui, L.Zhao, A.A.Kermani, S.Du, T.Pipatpolkai, M.Jiang, S.Chittori, Y.Z.Tan, J.Shi, L.Delemotte, J.Cui, J.Sun. Mechanisms of KCNQ1 Gating Modulation By KCNE1/3 For Cell-Specific Function. Cell Res. 2025.
ISSN: ISSN 1001-0602
PubMed: 40745202
DOI: 10.1038/S41422-025-01152-1