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Calcium in PDB 1mf4: Structure-Based Design of Potent and Selective Inhibitors of Phospholipase A2: Crystal Structure of the Complex Formed Between Phosholipase A2 From Naja Naja Sagittifera and A Designed Peptide Inhibitor at 1.9 A Resolution
Enzymatic activity of Structure-Based Design of Potent and Selective Inhibitors of Phospholipase A2: Crystal Structure of the Complex Formed Between Phosholipase A2 From Naja Naja Sagittifera and A Designed Peptide Inhibitor at 1.9 A Resolution
All present enzymatic activity of Structure-Based Design of Potent and Selective Inhibitors of Phospholipase A2: Crystal Structure of the Complex Formed Between Phosholipase A2 From Naja Naja Sagittifera and A Designed Peptide Inhibitor at 1.9 A Resolution:
3.1.1.4;
3.1.1.4;
Protein crystallography data
The structure of Structure-Based Design of Potent and Selective Inhibitors of Phospholipase A2: Crystal Structure of the Complex Formed Between Phosholipase A2 From Naja Naja Sagittifera and A Designed Peptide Inhibitor at 1.9 A Resolution, PDB code: 1mf4
was solved by
R.K.Singh,
P.Vikram,
M.Paramsivam,
T.Jabeen,
S.Sharma,
J.Makker,
S.Dey,
P.Kaur,
A.Srinivasan,
T.P.Singh,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 19.54 / 1.90 |
| Space group | P 41 |
| Cell size a, b, c (Å), α, β, γ (°) | 42.779, 42.779, 65.866, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 18.2 / 23.9 |
Calcium Binding Sites:
The binding sites of Calcium atom in the Structure-Based Design of Potent and Selective Inhibitors of Phospholipase A2: Crystal Structure of the Complex Formed Between Phosholipase A2 From Naja Naja Sagittifera and A Designed Peptide Inhibitor at 1.9 A Resolution
(pdb code 1mf4). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Structure-Based Design of Potent and Selective Inhibitors of Phospholipase A2: Crystal Structure of the Complex Formed Between Phosholipase A2 From Naja Naja Sagittifera and A Designed Peptide Inhibitor at 1.9 A Resolution, PDB code: 1mf4:
In total only one binding site of Calcium was determined in the Structure-Based Design of Potent and Selective Inhibitors of Phospholipase A2: Crystal Structure of the Complex Formed Between Phosholipase A2 From Naja Naja Sagittifera and A Designed Peptide Inhibitor at 1.9 A Resolution, PDB code: 1mf4:
Calcium binding site 1 out of 1 in 1mf4
Go back to
Calcium Binding Sites List in 1mf4
Calcium binding site 1 out
of 1 in the Structure-Based Design of Potent and Selective Inhibitors of Phospholipase A2: Crystal Structure of the Complex Formed Between Phosholipase A2 From Naja Naja Sagittifera and A Designed Peptide Inhibitor at 1.9 A Resolution
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Structure-Based Design of Potent and Selective Inhibitors of Phospholipase A2: Crystal Structure of the Complex Formed Between Phosholipase A2 From Naja Naja Sagittifera and A Designed Peptide Inhibitor at 1.9 A Resolution within 5.0Å range:
|
Reference:
R.K.Singh,
P.Vikram,
J.Makker,
T.Jabeen,
S.Sharma,
S.Dey,
P.Kaur,
A.Srinivasan,
T.P.Singh.
Design of Specific Peptide Inhibitors For Group I Phospholipase A2: Structure of A Complex Formed Between Phospholipase A2 From Naja Naja Sagittifera (Group I) and A Designed Peptide Inhibitor Val-Ala-Phe-Arg-Ser (Vafrs) at 1.9 A Resolution Reveals Unique Features Biochemistry V. 42 11701 2003.
ISSN: ISSN 0006-2960
PubMed: 14529280
DOI: 10.1021/BI035076X
Page generated: Mon Jul 7 17:18:00 2025
ISSN: ISSN 0006-2960
PubMed: 14529280
DOI: 10.1021/BI035076X
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