Calcium in PDB 1r9j: Transketolase From Leishmania Mexicana

All present enzymatic activity of Transketolase From Leishmania Mexicana:
2.2.1.1;

The structure of Transketolase From Leishmania Mexicana, PDB code: 1r9j was solved by N.J.Veitch, D.A.Mauger, J.J.Cazzulo, Y.Lindqvist, M.P.Barrett, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.00 / 2.22
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	76.800, 120.440, 139.150, 90.00, 90.00, 90.00
R / Rfree (%)	17 / 21.3

The binding sites of Calcium atom in the Transketolase From Leishmania Mexicana (pdb code 1r9j). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Transketolase From Leishmania Mexicana, PDB code: 1r9j:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Transketolase From Leishmania Mexicana


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Transketolase From Leishmania Mexicana within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1670 b:38.6 occ:1.00 O A:ILE187 2.5 27.9 1.0 OD2 A:ASP155 2.6 25.7 1.0 OD1 A:ASN185 2.6 30.6 1.0 O A:HOH1793 2.6 25.8 1.0 O2A A:TPP1671 2.7 33.1 1.0 O1B A:TPP1671 2.9 36.4 1.0 O3A A:TPP1671 2.9 35.8 1.0 CG A:ASN185 3.3 30.8 1.0 ND2 A:ASN185 3.4 28.6 1.0 CG A:ASP155 3.5 24.0 1.0 PA A:TPP1671 3.6 33.4 1.0 PB A:TPP1671 3.6 32.2 1.0 C A:ILE187 3.7 28.8 1.0 CB A:ASP155 3.7 20.0 1.0 N A:ILE187 3.9 29.0 1.0 N A:ASP155 4.0 17.3 1.0 O3B A:TPP1671 4.1 31.5 1.0 CA A:ILE187 4.3 29.1 1.0 O A:ASP183 4.4 24.5 1.0 N A:ASN185 4.5 24.6 1.0 O1A A:TPP1671 4.5 35.1 1.0 CA A:ASP155 4.5 19.3 1.0 O7 A:TPP1671 4.5 34.7 1.0 OD1 A:ASP155 4.6 28.0 1.0 CB A:ASN185 4.7 27.3 1.0 N A:TYR186 4.7 28.7 1.0 CB A:ILE187 4.7 29.0 1.0 N A:SER188 4.7 29.0 1.0 O2B A:TPP1671 4.8 35.0 1.0 C A:ASN185 4.9 26.5 1.0 CA A:ASN185 4.9 25.9 1.0 O A:HOH1939 5.0 25.4 1.0

Calcium binding site 2 out of 2 in the Transketolase From Leishmania Mexicana


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Transketolase From Leishmania Mexicana within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca2670 b:38.9 occ:1.00 OD1 B:ASN185 2.4 24.0 1.0 O B:ILE187 2.5 23.5 1.0 O B:HOH2836 2.6 20.9 1.0 OD2 B:ASP155 2.6 21.0 1.0 O2A B:TPP2671 2.7 28.8 1.0 O1B B:TPP2671 2.7 25.9 1.0 O3A B:TPP2671 3.1 28.9 1.0 CG B:ASN185 3.3 24.1 1.0 PB B:TPP2671 3.5 24.9 1.0 PA B:TPP2671 3.6 28.3 1.0 CG B:ASP155 3.6 21.5 1.0 ND2 B:ASN185 3.6 24.7 1.0 C B:ILE187 3.7 23.6 1.0 CB B:ASP155 3.9 19.4 1.0 N B:ILE187 4.0 23.3 1.0 O3B B:TPP2671 4.0 25.4 1.0 N B:ASP155 4.0 19.0 1.0 CA B:ILE187 4.3 22.7 1.0 O B:HOH2919 4.4 30.6 1.0 O B:ASP183 4.4 20.2 1.0 O7 B:TPP2671 4.5 31.9 1.0 N B:ASN185 4.5 21.2 1.0 O1A B:TPP2671 4.6 31.6 1.0 CA B:ASP155 4.6 19.8 1.0 CB B:ASN185 4.7 23.7 1.0 CB B:ILE187 4.7 21.8 1.0 OD1 B:ASP155 4.7 23.3 1.0 N B:SER188 4.7 24.0 1.0 N B:TYR186 4.8 24.2 1.0 O2B B:TPP2671 4.8 26.8 1.0 C B:ASN185 4.9 23.0 1.0 CA B:ASN185 4.9 23.0 1.0 CA B:SER188 5.0 25.2 1.0

N.J.Veitch, D.A.Maugeri, J.J.Cazzulo, Y.Lindqvist, M.P.Barrett. Transketolase From Leishmania Mexicana Has A Dual Subcellular Localization. Biochem.J. V. 382 759 2004.
ISSN: ISSN 0264-6021
PubMed: 15149284
DOI: 10.1042/BJ20040459