Calcium in PDB 2noe: Structure of Catalytically Inactive G42A Human 8-Oxoguanine Glycosylase Complexed to 8-Oxoguanine Dna

All present enzymatic activity of Structure of Catalytically Inactive G42A Human 8-Oxoguanine Glycosylase Complexed to 8-Oxoguanine Dna:
4.2.99.18;

The structure of Structure of Catalytically Inactive G42A Human 8-Oxoguanine Glycosylase Complexed to 8-Oxoguanine Dna, PDB code: 2noe was solved by C.T.Radom, A.Banerjee, G.L.Verdine, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.20
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	91.870, 91.870, 211.799, 90.00, 90.00, 120.00
R / Rfree (%)	22.6 / 26.9

The binding sites of Calcium atom in the Structure of Catalytically Inactive G42A Human 8-Oxoguanine Glycosylase Complexed to 8-Oxoguanine Dna (pdb code 2noe). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Structure of Catalytically Inactive G42A Human 8-Oxoguanine Glycosylase Complexed to 8-Oxoguanine Dna, PDB code: 2noe:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Structure of Catalytically Inactive G42A Human 8-Oxoguanine Glycosylase Complexed to 8-Oxoguanine Dna


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of Catalytically Inactive G42A Human 8-Oxoguanine Glycosylase Complexed to 8-Oxoguanine Dna within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca301 b:91.2 occ:1.00 O C:HOH308 3.0 49.3 1.0 OP2 C:DA24 3.1 60.5 1.0 O C:HOH309 3.5 49.0 1.0 C8 C:DA24 3.6 40.9 1.0 OP2 C:DG26 3.9 34.1 1.0 OP1 C:DG26 3.9 37.2 1.0 N7 C:DA24 4.0 40.7 1.0 N7 C:DG26 4.2 41.6 1.0 ND2 A:ASN149 4.3 44.5 1.0 P C:DG26 4.3 34.5 1.0 P C:DA24 4.5 59.8 1.0 C2' C:DA24 4.5 38.4 1.0 CB A:VAL269 4.6 37.8 1.0 O5' C:DA24 4.6 54.2 1.0 N9 C:DA24 4.7 38.1 1.0 C8 C:DG26 4.7 39.7 1.0 CG1 A:VAL269 4.8 39.6 1.0 O5' C:DG26 4.9 37.0 1.0

Calcium binding site 2 out of 2 in the Structure of Catalytically Inactive G42A Human 8-Oxoguanine Glycosylase Complexed to 8-Oxoguanine Dna


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of Catalytically Inactive G42A Human 8-Oxoguanine Glycosylase Complexed to 8-Oxoguanine Dna within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca302 b:95.8 occ:1.00 O A:CYS241 2.7 39.6 1.0 O A:HOH362 2.7 44.2 1.0 OP2 C:DC28 2.9 50.6 1.0 O A:VAL246 3.0 37.9 1.0 OP1 C:DC28 3.0 49.5 1.0 P C:DC28 3.4 51.5 1.0 C A:CYS241 3.8 40.8 1.0 O A:LEU243 4.0 42.1 1.0 C A:VAL246 4.1 38.5 1.0 CA A:CYS241 4.3 39.5 1.0 CB A:CYS241 4.5 40.9 1.0 O5' C:DC28 4.6 52.1 1.0 O3' C:DT27 4.6 50.3 1.0 CA A:GLY247 4.6 36.0 1.0 N A:GLY247 4.8 39.0 1.0 O A:ILE242 4.8 43.6 1.0 N A:ILE242 4.9 43.1 1.0 C A:ILE242 4.9 44.0 1.0 C3' C:DT27 5.0 48.3 1.0

C.T.Radom, A.Banerjee, G.L.Verdine. Structural Characterization of Human 8-Oxoguanine Dna Glycosylase Variants Bearing Active Site Mutations. J.Biol.Chem. V. 282 9182 2007.
ISSN: ISSN 0021-9258
PubMed: 17114185
DOI: 10.1074/JBC.M608989200