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Calcium in PDB 2noi: Structure of G42A Human 8-Oxoguanine Glycosylase Crosslinked to Undamaged G-Containing Dna

Enzymatic activity of Structure of G42A Human 8-Oxoguanine Glycosylase Crosslinked to Undamaged G-Containing Dna

All present enzymatic activity of Structure of G42A Human 8-Oxoguanine Glycosylase Crosslinked to Undamaged G-Containing Dna:
4.2.99.18;

Protein crystallography data

The structure of Structure of G42A Human 8-Oxoguanine Glycosylase Crosslinked to Undamaged G-Containing Dna, PDB code: 2noi was solved by C.T.Radom, A.Banerjee, G.L.Verdine, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 2.35
Space group P 65 2 2
Cell size a, b, c (Å), α, β, γ (°) 91.888, 91.888, 211.835, 90.00, 90.00, 120.00
R / Rfree (%) 22.6 / 25.9

Calcium Binding Sites:

The binding sites of Calcium atom in the Structure of G42A Human 8-Oxoguanine Glycosylase Crosslinked to Undamaged G-Containing Dna (pdb code 2noi). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Structure of G42A Human 8-Oxoguanine Glycosylase Crosslinked to Undamaged G-Containing Dna, PDB code: 2noi:

Calcium binding site 1 out of 1 in 2noi

Go back to Calcium Binding Sites List in 2noi
Calcium binding site 1 out of 1 in the Structure of G42A Human 8-Oxoguanine Glycosylase Crosslinked to Undamaged G-Containing Dna


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of G42A Human 8-Oxoguanine Glycosylase Crosslinked to Undamaged G-Containing Dna within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Ca301

b:70.4
occ:1.00
 O A:CYS241 2.5 47.2 1.0
OP1 C:DC26 2.7 64.8 1.0
O A:LEU243 2.7 46.0 1.0
O A:VAL246 2.9 44.8 1.0
OP2 C:DC26 3.2 66.5 1.0
P C:DC26 3.4 65.3 1.0
C A:CYS241 3.5 48.1 1.0
C A:LEU243 3.7 44.6 1.0
C A:VAL246 3.8 45.0 1.0
C A:ILE242 4.1 49.6 1.0
O A:ILE242 4.1 51.0 1.0
N A:VAL246 4.1 43.0 1.0
O3' C:DT25 4.3 65.5 1.0
CA A:CYS241 4.3 46.1 1.0
N A:LEU243 4.3 47.2 1.0
CA A:VAL246 4.4 43.4 1.0
N A:ILE242 4.4 49.7 1.0
CA A:PRO244 4.5 44.9 1.0
N A:GLY245 4.5 46.5 1.0
N A:PRO244 4.5 44.6 1.0
CA A:ILE242 4.6 50.0 1.0
N A:GLY247 4.6 44.9 1.0
CA A:LEU243 4.7 45.1 1.0
O5' C:DC26 4.7 65.8 1.0
CB A:VAL246 4.7 44.0 1.0
CA A:GLY247 4.9 41.2 1.0
CB A:CYS241 4.9 47.2 1.0
C A:PRO244 4.9 46.6 1.0

Reference:

C.T.Radom, A.Banerjee, G.L.Verdine. Structural Characterization of Human 8-Oxoguanine Dna Glycosylase Variants Bearing Active Site Mutations. J.Biol.Chem. V. 282 9182 2007.
ISSN: ISSN 0021-9258
PubMed: 17114185
DOI: 10.1074/JBC.M608989200
Page generated: Tue Jul 8 07:12:04 2025

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