Calcium in PDB 3coa: Crystal Structure of FOXO1 Dbd Bound to Ire Dna

The structure of Crystal Structure of FOXO1 Dbd Bound to Ire Dna, PDB code: 3coa was solved by M.M.Brent, R.Anand, R.Marmorstein, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.20
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	76.062, 102.432, 65.446, 90.00, 90.00, 90.00
R / Rfree (%)	21.6 / 25

The binding sites of Calcium atom in the Crystal Structure of FOXO1 Dbd Bound to Ire Dna (pdb code 3coa). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of FOXO1 Dbd Bound to Ire Dna, PDB code: 3coa:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of FOXO1 Dbd Bound to Ire Dna


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of FOXO1 Dbd Bound to Ire Dna within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca1 b:50.8 occ:1.00 O C:LEU217 2.8 14.7 1.0 O C:PHE223 2.9 19.9 1.0 O C:HIS220 2.9 23.7 1.0 O C:SER218 3.1 20.6 1.0 O C:HOH275 3.1 23.0 1.0 O A:HOH14 3.2 38.2 1.0 C C:SER218 3.7 19.4 1.0 C C:HIS220 3.8 24.9 1.0 C C:PHE223 3.9 20.6 1.0 C C:LEU217 3.9 16.2 1.0 CA C:SER218 3.9 20.0 1.0 O C:HOH278 4.1 28.2 1.0 CB C:PHE223 4.4 17.4 1.0 N C:HIS220 4.4 23.6 1.0 CZ3 C:TRP237 4.4 10.5 1.0 N C:SER218 4.4 16.4 1.0 N C:SER221 4.5 24.6 1.0 CA C:SER221 4.5 25.1 1.0 CA C:PHE223 4.6 20.2 1.0 N C:LEU219 4.6 20.8 1.0 C C:LEU219 4.7 23.7 1.0 N C:PHE223 4.7 21.2 1.0 CA C:HIS220 4.7 24.1 1.0 O C:HOH308 4.7 41.4 1.0 N C:ILE224 4.8 19.2 1.0 CA C:ILE224 4.9 21.4 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of FOXO1 Dbd Bound to Ire Dna


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of FOXO1 Dbd Bound to Ire Dna within 5.0Å range: probe atom residue distance (Å) B Occ F:Ca2 b:55.5 occ:1.00 O F:PHE223 2.8 17.0 1.0 O F:LEU217 2.9 18.0 1.0 O F:HIS220 3.1 20.9 1.0 O D:HOH13 3.1 18.8 1.0 O F:HOH267 3.2 39.0 1.0 O F:SER218 3.2 19.4 1.0 C F:SER218 3.8 18.6 1.0 C F:HIS220 3.8 21.7 1.0 C F:PHE223 3.9 19.3 1.0 O F:HOH317 4.0 40.3 1.0 C F:LEU217 4.0 17.6 1.0 CA F:SER218 4.1 19.4 1.0 O F:HOH296 4.3 36.5 1.0 CA F:SER221 4.4 23.2 1.0 N F:SER221 4.5 21.5 1.0 N F:HIS220 4.5 21.1 1.0 CB F:PHE223 4.5 15.3 1.0 N F:SER218 4.5 17.0 1.0 CZ3 F:TRP237 4.5 12.6 1.0 CA F:PHE223 4.7 18.4 1.0 C F:LEU219 4.7 21.0 1.0 N F:LEU219 4.7 20.4 1.0 N F:PHE223 4.7 19.4 1.0 CA F:HIS220 4.7 22.5 1.0 N F:ILE224 4.8 18.8 1.0 CA F:ILE224 4.8 20.9 1.0 C F:SER221 4.9 23.3 1.0 O F:LEU219 5.0 22.1 1.0

M.M.Brent, R.Anand, R.Marmorstein. Structural Basis For Dna Recognition By FOXO1 and Its Regulation By Posttranslational Modification. Structure V. 16 1407 2008.
ISSN: ISSN 0969-2126
PubMed: 18786403
DOI: 10.1016/J.STR.2008.06.013