Calcium in PDB 3vrn: Crystal Structure of the Tyrosine Kinase Binding Domain of Cbl-C

The structure of Crystal Structure of the Tyrosine Kinase Binding Domain of Cbl-C, PDB code: 3vrn was solved by K.Takeshita, T.Tezuka, Y.Isozaki, E.Yamashita, M.Suzuki, Y.Yamanashi, T.Yamamoto, A.Nakagawa, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.24 / 1.64
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	93.223, 107.617, 54.773, 90.00, 90.00, 90.00
R / Rfree (%)	18.2 / 21.8

The binding sites of Calcium atom in the Crystal Structure of the Tyrosine Kinase Binding Domain of Cbl-C (pdb code 3vrn). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Crystal Structure of the Tyrosine Kinase Binding Domain of Cbl-C, PDB code: 3vrn:

Calcium binding site 1 out of 1 in the Crystal Structure of the Tyrosine Kinase Binding Domain of Cbl-C


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of the Tyrosine Kinase Binding Domain of Cbl-C within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca401 b:14.4 occ:0.65 OD1 A:ASP199 2.3 11.5 1.0 O A:HIS205 2.4 12.6 1.0 O A:HOH519 2.4 15.7 1.0 OE2 A:GLU210 2.5 17.0 1.0 OG A:SER203 2.6 9.5 1.0 OG1 A:THR201 2.6 11.9 1.0 OE1 A:GLU210 2.7 18.7 1.0 CD A:GLU210 3.0 16.9 1.0 CG A:ASP199 3.4 13.1 1.0 C A:HIS205 3.6 10.6 1.0 CB A:SER203 3.6 11.7 1.0 CB A:THR201 3.9 9.2 1.0 N A:SER203 3.9 10.0 1.0 O A:HOH509 3.9 15.5 1.0 N A:THR201 4.0 10.3 1.0 N A:HIS205 4.1 9.4 1.0 O A:HOH506 4.1 15.3 1.0 OD2 A:ASP199 4.2 14.8 1.0 CA A:ASP199 4.3 9.9 1.0 CA A:SER203 4.3 9.6 1.0 CA A:THR201 4.3 9.6 1.0 N A:CYS202 4.4 9.5 1.0 CA A:HIS205 4.4 10.1 1.0 CB A:ASP199 4.4 11.1 1.0 CG A:GLU210 4.4 10.7 1.0 CG2 A:THR201 4.5 12.3 1.0 OE2 A:GLU134 4.5 13.5 1.0 C A:ASP199 4.5 11.4 1.0 C A:THR201 4.5 10.6 1.0 N A:GLY204 4.5 10.3 1.0 N A:VAL206 4.5 8.8 1.0 CA A:VAL206 4.6 7.0 1.0 N A:LEU200 4.6 10.7 1.0 C A:SER203 4.7 10.3 1.0 CB A:HIS205 4.8 11.4 1.0 N A:SER207 4.9 8.6 1.0

K.Takeshita, T.Tezuka, Y.Isozaki, E.Yamashita, M.Suzuki, M.Kim, Y.Yamanashi, T.Yamamoto, A.Nakagawa. Structural Flexibility Regulates Phosphopeptide-Binding Activity of the Tyrosine Kinase Binding Domain of Cbl-C J.Biochem. V. 152 487 2012.
ISSN: ISSN 0021-924X
PubMed: 22888118
DOI: 10.1093/JB/MVS085