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Calcium in PDB 4ed3: Human Dna Polymerase Eta - Dna Ternary Complex: at Crystal at pH 7.5 (Na+ Hepes) with 1 CA2+ Ion

Enzymatic activity of Human Dna Polymerase Eta - Dna Ternary Complex: at Crystal at pH 7.5 (Na+ Hepes) with 1 CA2+ Ion

All present enzymatic activity of Human Dna Polymerase Eta - Dna Ternary Complex: at Crystal at pH 7.5 (Na+ Hepes) with 1 CA2+ Ion:
2.7.7.7;

Protein crystallography data

The structure of Human Dna Polymerase Eta - Dna Ternary Complex: at Crystal at pH 7.5 (Na+ Hepes) with 1 CA2+ Ion, PDB code: 4ed3 was solved by T.Nakamura, Y.Zhao, W.Yang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 28.52 / 1.79
Space group P 61
Cell size a, b, c (Å), α, β, γ (°) 98.786, 98.786, 82.431, 90.00, 90.00, 120.00
R / Rfree (%) 16.7 / 21.6

Other elements in 4ed3:

The structure of Human Dna Polymerase Eta - Dna Ternary Complex: at Crystal at pH 7.5 (Na+ Hepes) with 1 CA2+ Ion also contains other interesting chemical elements:

Sodium (Na) 1 atom

Calcium Binding Sites:

The binding sites of Calcium atom in the Human Dna Polymerase Eta - Dna Ternary Complex: at Crystal at pH 7.5 (Na+ Hepes) with 1 CA2+ Ion (pdb code 4ed3). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Human Dna Polymerase Eta - Dna Ternary Complex: at Crystal at pH 7.5 (Na+ Hepes) with 1 CA2+ Ion, PDB code: 4ed3:

Calcium binding site 1 out of 1 in 4ed3

Go back to Calcium Binding Sites List in 4ed3
Calcium binding site 1 out of 1 in the Human Dna Polymerase Eta - Dna Ternary Complex: at Crystal at pH 7.5 (Na+ Hepes) with 1 CA2+ Ion


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human Dna Polymerase Eta - Dna Ternary Complex: at Crystal at pH 7.5 (Na+ Hepes) with 1 CA2+ Ion within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca503

b:12.3
occ:1.00
 O1B P:DTP501 2.3 8.2 1.0
O A:MET14 2.3 9.3 1.0
O3G P:DTP501 2.4 11.4 1.0
OD1 A:ASP115 2.4 14.8 1.0
O2A P:DTP501 2.4 11.5 1.0
OD1 A:ASP13 2.5 19.2 1.0
OD2 A:ASP13 2.6 19.9 1.0
CG A:ASP13 2.9 13.7 1.0
PB P:DTP501 3.4 11.3 1.0
CG A:ASP115 3.4 13.8 1.0
NA A:NA502 3.5 21.1 1.0
C A:MET14 3.5 10.5 1.0
PA P:DTP501 3.5 11.7 1.0
PG P:DTP501 3.5 12.0 1.0
O3A P:DTP501 3.6 14.8 1.0
OD2 A:ASP115 3.7 13.9 1.0
O3B P:DTP501 3.9 11.9 1.0
N A:MET14 4.0 9.8 1.0
O A:HOH676 4.0 25.4 1.0
NZ A:LYS231 4.0 14.8 1.0
O2G P:DTP501 4.1 10.8 1.0
C5' P:DTP501 4.2 9.2 1.0
CA A:MET14 4.3 12.3 1.0
CB A:ASP13 4.3 14.3 1.0
C A:ASP13 4.3 10.8 1.0
O5' P:DTP501 4.4 9.6 1.0
N A:ASP15 4.5 9.3 1.0
N A:CYS16 4.6 8.7 1.0
CA A:ASP15 4.6 10.7 1.0
O A:HOH725 4.6 25.4 1.0
CB A:ASP115 4.7 11.4 1.0
O A:ASP13 4.7 11.7 1.0
C A:ASP15 4.7 10.4 1.0
O2B P:DTP501 4.8 11.7 1.0
CA A:ASP13 4.8 12.8 1.0
O1G P:DTP501 4.8 14.1 1.0
O1A P:DTP501 4.8 13.6 1.0
CE A:LYS231 4.8 26.4 1.0
CB A:MET14 4.8 10.2 1.0
N A:PHE17 4.8 7.0 1.0
CB A:PHE17 4.9 7.8 1.0
O A:ASP115 5.0 15.1 1.0

Reference:

T.Nakamura, Y.Zhao, Y.Yamagata, Y.J.Hua, W.Yang. Watching Dna Polymerase Eta Make A Phosphodiester Bond Nature V. 487 196 2012.
ISSN: ISSN 0028-0836
PubMed: 22785315
DOI: 10.1038/NATURE11181
Page generated: Tue Jul 8 19:45:22 2025

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