Calcium in PDB 4gjf: Crystal Structure of the Amino-Terminal Domain of Human Cardiac Troponin C Mutant L29Q in Complex with Cadmium

The structure of Crystal Structure of the Amino-Terminal Domain of Human Cardiac Troponin C Mutant L29Q in Complex with Cadmium, PDB code: 4gjf was solved by X.Zhang, M.Paetzel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.65 / 1.90
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	49.250, 49.250, 113.378, 90.00, 90.00, 120.00
R / Rfree (%)	14.2 / 17.8

The structure of Crystal Structure of the Amino-Terminal Domain of Human Cardiac Troponin C Mutant L29Q in Complex with Cadmium also contains other interesting chemical elements:

Cadmium

(Cd)

8 atoms

The binding sites of Calcium atom in the Crystal Structure of the Amino-Terminal Domain of Human Cardiac Troponin C Mutant L29Q in Complex with Cadmium (pdb code 4gjf). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Crystal Structure of the Amino-Terminal Domain of Human Cardiac Troponin C Mutant L29Q in Complex with Cadmium, PDB code: 4gjf:

Calcium binding site 1 out of 1 in the Crystal Structure of the Amino-Terminal Domain of Human Cardiac Troponin C Mutant L29Q in Complex with Cadmium


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of the Amino-Terminal Domain of Human Cardiac Troponin C Mutant L29Q in Complex with Cadmium within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca101 b:0.4 occ:0.50 O A:HOH234 2.3 99.8 1.0 O A:HOH233 3.7 63.8 1.0 CG A:GLU19 4.3 42.9 1.0 CD A:GLU15 4.3 56.6 1.0 CB A:GLU15 4.3 40.8 1.0 OE1 A:GLU15 4.3 55.2 1.0 CG A:GLU15 4.5 47.2 1.0 CD A:GLU19 4.6 50.4 1.0 OE1 A:GLU19 4.6 56.1 1.0 OE2 A:GLU15 4.6 60.6 1.0

X.L.Zhang, G.F.Tibbits, M.Paetzel. The Structure of Cardiac Troponin C Regulatory Domain with Bound Cd(2+) Reveals A Closed Conformation and Unique Ion Coordination. Acta Crystallogr.,Sect.D V. 69 722 2013.
ISSN: ISSN 0907-4449
PubMed: 23633581
DOI: 10.1107/S0907444913001182