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Atomistry » Calcium » PDB 4gq7-4gzs » 4guy | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Calcium » PDB 4gq7-4gzs » 4guy » |
Calcium in PDB 4guy: Human MMP12 Catalytic Domain in Complex with*N*-Hydroxy-2-(2-(4- Methoxyphenyl)Ethylsulfonamido)AcetamideEnzymatic activity of Human MMP12 Catalytic Domain in Complex with*N*-Hydroxy-2-(2-(4- Methoxyphenyl)Ethylsulfonamido)Acetamide
All present enzymatic activity of Human MMP12 Catalytic Domain in Complex with*N*-Hydroxy-2-(2-(4- Methoxyphenyl)Ethylsulfonamido)Acetamide:
3.4.24.65; Protein crystallography data
The structure of Human MMP12 Catalytic Domain in Complex with*N*-Hydroxy-2-(2-(4- Methoxyphenyl)Ethylsulfonamido)Acetamide, PDB code: 4guy
was solved by
V.Calderone,
M.Fragai,
C.Luchinat,
A.Massaro,
A.Mordini,
M.Mori,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4guy:
The structure of Human MMP12 Catalytic Domain in Complex with*N*-Hydroxy-2-(2-(4- Methoxyphenyl)Ethylsulfonamido)Acetamide also contains other interesting chemical elements:
Calcium Binding Sites:
The binding sites of Calcium atom in the Human MMP12 Catalytic Domain in Complex with*N*-Hydroxy-2-(2-(4- Methoxyphenyl)Ethylsulfonamido)Acetamide
(pdb code 4guy). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Human MMP12 Catalytic Domain in Complex with*N*-Hydroxy-2-(2-(4- Methoxyphenyl)Ethylsulfonamido)Acetamide, PDB code: 4guy: Jump to Calcium binding site number: 1; 2; 3; Calcium binding site 1 out of 3 in 4guyGo back to![]() ![]()
Calcium binding site 1 out
of 3 in the Human MMP12 Catalytic Domain in Complex with*N*-Hydroxy-2-(2-(4- Methoxyphenyl)Ethylsulfonamido)Acetamide
![]() Mono view ![]() Stereo pair view
Calcium binding site 2 out of 3 in 4guyGo back to![]() ![]()
Calcium binding site 2 out
of 3 in the Human MMP12 Catalytic Domain in Complex with*N*-Hydroxy-2-(2-(4- Methoxyphenyl)Ethylsulfonamido)Acetamide
![]() Mono view ![]() Stereo pair view
Calcium binding site 3 out of 3 in 4guyGo back to![]() ![]()
Calcium binding site 3 out
of 3 in the Human MMP12 Catalytic Domain in Complex with*N*-Hydroxy-2-(2-(4- Methoxyphenyl)Ethylsulfonamido)Acetamide
![]() Mono view ![]() Stereo pair view
Reference:
M.Mori,
A.Massaro,
V.Calderone,
M.Fragai,
C.Luchinat,
A.Mordini.
Contribution of Free Energy of Solvation to Ligand Affinity in New Potent Mmps Inhibitors. To Be Published.
Page generated: Tue Jul 8 22:25:16 2025
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