Calcium in PDB 4o3m: Ternary Complex of Bloom'S Syndrome Helicase

All present enzymatic activity of Ternary Complex of Bloom'S Syndrome Helicase:
3.6.4.12;

The structure of Ternary Complex of Bloom'S Syndrome Helicase, PDB code: 4o3m was solved by M.K.Swan, J.Bertrand, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.91 / 2.30
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	100.930, 164.680, 50.980, 90.00, 90.14, 90.00
R / Rfree (%)	18.1 / 21.5

The structure of Ternary Complex of Bloom'S Syndrome Helicase also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Calcium atom in the Ternary Complex of Bloom'S Syndrome Helicase (pdb code 4o3m). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Ternary Complex of Bloom'S Syndrome Helicase, PDB code: 4o3m:

Calcium binding site 1 out of 1 in the Ternary Complex of Bloom'S Syndrome Helicase


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Ternary Complex of Bloom'S Syndrome Helicase within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1301 b:0.9 occ:1.00 O A:HOH1404 2.5 93.9 1.0 O A:HOH1403 2.5 62.0 1.0 O A:HOH1443 2.7 62.4 1.0 O1B A:ADP1303 2.7 65.5 1.0 PB A:ADP1303 4.0 64.0 1.0 OG A:SER696 4.0 61.9 1.0 OD1 A:ASP795 4.0 94.9 1.0 O3B A:ADP1303 4.1 60.0 1.0 NE2 A:GLN723 4.2 85.0 1.0 OD2 A:ASP795 4.4 0.4 1.0 O2A A:ADP1303 4.6 66.8 1.0 CG A:ASP795 4.6 94.2 1.0 O3A A:ADP1303 4.9 61.1 1.0

M.K.Swan, V.Legris, A.Tanner, P.M.Reaper, S.Vial, R.Bordas, J.R.Pollard, P.A.Charlton, J.M.Golec, J.A.Bertrand. Structure of Human Bloom'S Syndrome Helicase in Complex with Adp and Duplex Dna. Acta Crystallogr.,Sect.D V. 70 1465 2014.
ISSN: ISSN 0907-4449
PubMed: 24816114
DOI: 10.1107/S139900471400501X