Calcium in PDB 4o4j: Tubulin-Peloruside A Complex

The structure of Tubulin-Peloruside A Complex, PDB code: 4o4j was solved by A.E.Prota, K.Bargsten, P.T.Northcote, M.Marsh, K.H.Altmann, J.H.Miller, J.F.Diaz, M.O.Steinmetz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	72.30 / 2.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	104.370, 157.840, 180.360, 90.00, 90.00, 90.00
R / Rfree (%)	20.1 / 23.9

The structure of Tubulin-Peloruside A Complex also contains other interesting chemical elements:

Magnesium

(Mg)

4 atoms

The binding sites of Calcium atom in the Tubulin-Peloruside A Complex (pdb code 4o4j). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Tubulin-Peloruside A Complex, PDB code: 4o4j:

Calcium binding site 1 out of 1 in the Tubulin-Peloruside A Complex


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Tubulin-Peloruside A Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca503 b:68.5 occ:1.00 O A:GLY44 2.5 62.7 1.0 OD2 A:ASP39 2.6 49.4 1.0 OE2 A:GLU55 2.7 51.0 1.0 OD1 A:ASP39 2.7 51.5 1.0 CG A:ASP39 3.0 50.9 1.0 OG1 A:THR41 3.1 53.5 1.0 OE1 A:GLU55 3.3 56.6 1.0 CB A:THR41 3.3 61.4 1.0 CD A:GLU55 3.3 52.0 1.0 O A:THR41 3.5 67.0 1.0 C A:GLY44 3.6 66.9 1.0 CA A:GLY45 3.7 70.1 1.0 OD1 A:ASN50 3.8 44.1 1.0 CZ A:PHE49 4.0 51.1 1.0 OD1 A:ASP47 4.0 66.2 1.0 N A:GLY45 4.1 72.0 1.0 C A:THR41 4.1 67.2 1.0 CA A:THR41 4.2 67.2 1.0 OD2 A:ASP47 4.2 56.9 1.0 CG A:ASP47 4.3 58.1 1.0 ND2 A:ASN50 4.4 41.3 1.0 CG2 A:THR41 4.5 62.0 1.0 CB A:ASP39 4.5 48.9 1.0 CE2 A:PHE49 4.5 56.1 1.0 N A:THR41 4.5 67.3 1.0 CG A:ASN50 4.5 41.1 1.0 C A:GLY45 4.7 66.7 1.0 CG A:GLU55 4.7 46.6 1.0 CA A:GLY44 4.8 61.4 1.0 NE2 A:HIS61 4.8 56.3 1.0 CE1 A:PHE49 4.9 49.8 1.0

A.E.Prota, K.Bargsten, P.T.Northcote, M.Marsh, K.H.Altmann, J.H.Miller, J.F.Diaz, M.O.Steinmetz. Structural Basis of Microtubule Stabilization By Laulimalide and Peloruside A. Angew.Chem.Int.Ed.Engl. V. 53 1621 2014.
ISSN: ISSN 1433-7851
PubMed: 24470331
DOI: 10.1002/ANIE.201307749