Calcium in PDB 4p5w: Structure of the N- and C-Terminal Domain Fusion of the Human Mitochondrial Aspartate/Glutamate Carrier Citrin in the Calcium-Bound State

The structure of Structure of the N- and C-Terminal Domain Fusion of the Human Mitochondrial Aspartate/Glutamate Carrier Citrin in the Calcium-Bound State, PDB code: 4p5w was solved by C.Thangaratnarajah, J.J.Ruprecht, E.R.S.Kunji, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	53.08 / 2.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	68.149, 106.167, 117.888, 90.00, 90.00, 90.00
R / Rfree (%)	19.3 / 22.7

The binding sites of Calcium atom in the Structure of the N- and C-Terminal Domain Fusion of the Human Mitochondrial Aspartate/Glutamate Carrier Citrin in the Calcium-Bound State (pdb code 4p5w). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Structure of the N- and C-Terminal Domain Fusion of the Human Mitochondrial Aspartate/Glutamate Carrier Citrin in the Calcium-Bound State, PDB code: 4p5w:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Structure of the N- and C-Terminal Domain Fusion of the Human Mitochondrial Aspartate/Glutamate Carrier Citrin in the Calcium-Bound State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of the N- and C-Terminal Domain Fusion of the Human Mitochondrial Aspartate/Glutamate Carrier Citrin in the Calcium-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1001 b:73.3 occ:1.00 OG1 A:THR68 2.3 83.4 1.0 OE1 A:GLU77 2.3 69.4 1.0 OD1 A:ASP70 2.3 81.1 1.0 OD1 A:ASP66 2.4 75.3 1.0 O A:LEU72 2.4 62.9 1.0 OE2 A:GLU77 2.4 83.6 1.0 CD A:GLU77 2.7 73.0 1.0 CG A:ASP70 3.2 78.8 1.0 OD2 A:ASP70 3.4 72.9 1.0 CG A:ASP66 3.4 64.4 1.0 C A:LEU72 3.5 69.2 1.0 CB A:THR68 3.7 74.7 1.0 N A:THR68 4.1 65.8 1.0 CB A:ASP66 4.2 52.8 1.0 CA A:ASP66 4.2 53.6 1.0 CG A:GLU77 4.2 65.6 1.0 N A:SER74 4.2 75.0 1.0 CA A:ILE73 4.2 62.4 1.0 N A:ILE73 4.2 66.8 1.0 OD2 A:ASP66 4.2 64.0 1.0 CG2 A:THR68 4.3 59.7 1.0 CA A:THR68 4.4 64.3 1.0 N A:LEU72 4.4 73.5 1.0 CA A:LEU72 4.4 74.1 1.0 N A:ASP70 4.5 70.4 1.0 CB A:ASP70 4.5 65.5 1.0 N A:GLN67 4.5 64.6 1.0 N A:LYS69 4.6 66.7 1.0 C A:ASP66 4.6 64.5 1.0 OG A:SER74 4.7 63.9 1.0 C A:THR68 4.7 71.0 1.0 C A:ILE73 4.7 68.5 1.0 CB A:LEU72 4.8 78.2 1.0 CB A:SER74 5.0 62.4 1.0

Calcium binding site 2 out of 2 in the Structure of the N- and C-Terminal Domain Fusion of the Human Mitochondrial Aspartate/Glutamate Carrier Citrin in the Calcium-Bound State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of the N- and C-Terminal Domain Fusion of the Human Mitochondrial Aspartate/Glutamate Carrier Citrin in the Calcium-Bound State within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1001 b:85.4 occ:1.00 O B:LEU72 2.3 62.0 1.0 OD1 B:ASP70 2.4 0.3 1.0 OD1 B:ASP66 2.4 83.5 1.0 OE1 B:GLU77 2.4 90.8 1.0 OG1 B:THR68 2.4 79.2 1.0 OE2 B:GLU77 2.4 91.0 1.0 CD B:GLU77 2.7 87.0 1.0 CG B:ASP70 3.2 94.2 1.0 C B:LEU72 3.3 90.1 1.0 CG B:ASP66 3.5 66.2 1.0 OD2 B:ASP70 3.5 96.6 1.0 CB B:THR68 3.8 83.0 1.0 CA B:ILE73 4.1 91.1 1.0 N B:ILE73 4.1 91.6 1.0 N B:THR68 4.1 57.9 1.0 N B:SER74 4.2 86.5 1.0 CG B:GLU77 4.2 72.7 1.0 CA B:ASP66 4.2 69.1 1.0 CB B:ASP66 4.2 62.1 1.0 CA B:LEU72 4.2 93.2 1.0 N B:LEU72 4.3 92.2 1.0 OD2 B:ASP66 4.3 71.8 1.0 CA B:THR68 4.4 71.3 1.0 CG2 B:THR68 4.4 59.1 1.0 N B:ASP70 4.5 86.1 1.0 N B:LYS69 4.5 81.5 1.0 N B:GLN67 4.5 65.7 1.0 CB B:ASP70 4.6 89.5 1.0 C B:ASP66 4.6 69.9 1.0 CB B:LEU72 4.6 94.9 1.0 C B:ILE73 4.7 91.7 1.0 C B:THR68 4.7 81.4 1.0 OG B:SER74 4.7 73.3 1.0

C.Thangaratnarajah, J.J.Ruprecht, E.R.S.Kunji. Structure of the N- and C-Terminal Domain Fusion of the Human Mitochondrial Aspartate/Glutamate Carrier Citrin in the Calcium-Bound State Nat Commun 2014.
ISSN: ESSN 2041-1723
DOI: 10.1038/NCOMMS6491