Calcium in PDB 4xhu: The Complex Structure of TIMELESS_PAB and Parp-1_CATALYTIC Domain

All present enzymatic activity of The Complex Structure of TIMELESS_PAB and Parp-1_CATALYTIC Domain:
2.4.2.30;

The structure of The Complex Structure of TIMELESS_PAB and Parp-1_CATALYTIC Domain, PDB code: 4xhu was solved by S.Xie, C.Qian, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.10 / 2.09
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	99.364, 98.416, 116.900, 90.00, 113.19, 90.00
R / Rfree (%)	18.3 / 21.1

The binding sites of Calcium atom in the The Complex Structure of TIMELESS_PAB and Parp-1_CATALYTIC Domain (pdb code 4xhu). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the The Complex Structure of TIMELESS_PAB and Parp-1_CATALYTIC Domain, PDB code: 4xhu:

Calcium binding site 1 out of 1 in the The Complex Structure of TIMELESS_PAB and Parp-1_CATALYTIC Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of The Complex Structure of TIMELESS_PAB and Parp-1_CATALYTIC Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1103 b:94.8 occ:1.00 O A:HOH1220 2.8 41.8 1.0 OD2 A:ASP766 3.4 49.0 1.0 O2 A:GOL1101 3.7 67.3 1.0 CE2 A:TYR889 4.0 41.9 1.0 N A:ALA880 4.1 36.0 1.0 CG A:ASP766 4.1 46.6 1.0 O A:GLY894 4.3 31.5 1.0 O A:HOH1282 4.3 58.5 1.0 O A:HOH1226 4.3 29.4 1.0 CB A:ALA880 4.3 36.2 1.0 CD2 A:TYR889 4.5 40.5 1.0 O A:ARG878 4.5 34.7 1.0 OD1 A:ASP766 4.6 49.9 1.0 CA A:ALA880 4.7 39.0 1.0 CB A:ASP766 4.8 41.0 1.0 C A:ILE879 4.9 36.1 1.0 CZ A:TYR889 4.9 40.9 1.0 CA A:ILE879 5.0 35.8 1.0

S.Xie, O.Mortusewicz, H.T.Ma, P.Herr, R.R.Poon, T.Helleday, C.Qian. Timeless Interacts with Parp-1 to Promote Homologous Recombination Repair. Mol.Cell V. 60 163 2015.
ISSN: ISSN 1097-2765
PubMed: 26344098
DOI: 10.1016/J.MOLCEL.2015.07.031