Calcium in PDB 5ijq: Crystal Structure of Autotaxin (ENPP2) Re-Refined

All present enzymatic activity of Crystal Structure of Autotaxin (ENPP2) Re-Refined:
3.1.4.39;

The structure of Crystal Structure of Autotaxin (ENPP2) Re-Refined, PDB code: 5ijq was solved by J.Hausmann, R.P.Joosten, A.Perrakis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.05
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	53.808, 63.289, 70.471, 98.78, 106.22, 99.77
R / Rfree (%)	15.4 / 19.7

The structure of Crystal Structure of Autotaxin (ENPP2) Re-Refined also contains other interesting chemical elements:

Zinc	(Zn)	2 atoms
Iodine	(I)	25 atoms
Sodium	(Na)	2 atoms

The binding sites of Calcium atom in the Crystal Structure of Autotaxin (ENPP2) Re-Refined (pdb code 5ijq). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Crystal Structure of Autotaxin (ENPP2) Re-Refined, PDB code: 5ijq:

Calcium binding site 1 out of 1 in the Crystal Structure of Autotaxin (ENPP2) Re-Refined


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Autotaxin (ENPP2) Re-Refined within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca909 b:27.9 occ:1.00 OD1 A:ASP739 2.2 26.3 1.0 OD1 A:ASN741 2.3 29.9 1.0 OD1 A:ASP747 2.3 28.4 1.0 O A:LEU745 2.3 27.8 1.0 O A:HOH1142 2.3 34.4 1.0 OD1 A:ASP743 2.4 27.8 1.0 CG A:ASP743 3.3 30.3 1.0 CG A:ASP739 3.4 27.6 1.0 CG A:ASN741 3.4 33.9 1.0 C A:LEU745 3.5 25.3 1.0 CG A:ASP747 3.6 33.6 1.0 OD2 A:ASP743 3.7 33.0 1.0 ND2 A:ASN741 3.9 35.4 1.0 CA A:ASP739 3.9 30.5 1.0 N A:ASP747 3.9 31.8 1.0 N A:LEU745 4.1 24.8 1.0 C A:ARG746 4.1 31.7 1.0 CA A:ASP747 4.1 32.8 1.0 CB A:ASP739 4.1 27.1 1.0 CA A:LEU745 4.2 27.6 1.0 O A:ARG746 4.3 28.4 1.0 OD2 A:ASP739 4.3 24.9 1.0 N A:ASP743 4.4 24.7 1.0 OD2 A:ASP747 4.4 33.9 1.0 CB A:ASP747 4.4 32.4 1.0 C A:ASP739 4.4 29.8 1.0 O A:PHE738 4.4 28.0 1.0 N A:ARG746 4.5 26.5 1.0 CB A:LEU745 4.5 28.1 1.0 N A:ASN741 4.5 31.3 1.0 CB A:ASP743 4.6 28.0 1.0 OE1 A:GLU751 4.6 52.0 1.0 CB A:ASN741 4.7 33.0 1.0 N A:TYR740 4.7 29.4 1.0 CA A:ARG746 4.7 29.9 1.0 N A:TYR742 4.8 26.0 1.0 CA A:ASP743 4.8 25.2 1.0 C A:ASN741 4.9 28.7 1.0 CA A:ASN741 4.9 29.9 1.0 N A:GLY744 4.9 26.0 1.0

J.Hausmann, W.J.Keune, A.L.Hipgrave Ederveen, L.Van Zeijl, R.P.Joosten, A.Perrakis. Structural Snapshots of the Catalytic Cycle of the Phosphodiesterase Autotaxin. J.Struct.Biol. V. 195 199 2016.
ISSN: ESSN 1095-8657
PubMed: 27268273
DOI: 10.1016/J.JSB.2016.06.002