Calcium in PDB 6cno: Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II
Calcium Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
12;
Binding sites:
The binding sites of Calcium atom in the Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II
(pdb code 6cno). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 12 binding sites of Calcium where determined in the
Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II, PDB code: 6cno:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Calcium binding site 1 out
of 12 in 6cno
Go back to
Calcium Binding Sites List in 6cno
Calcium binding site 1 out
of 12 in the Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca201
b:0.5
occ:1.00
|
OD2
|
E:ASP24
|
2.0
|
0.1
|
1.0
|
|
CG
|
E:ASP24
|
2.1
|
0.1
|
1.0
|
|
OD1
|
E:ASP24
|
2.1
|
0.1
|
1.0
|
|
OE2
|
E:GLU31
|
2.2
|
0.7
|
1.0
|
|
OE1
|
E:GLU31
|
2.3
|
0.7
|
1.0
|
|
OD1
|
E:ASP20
|
2.3
|
0.6
|
1.0
|
|
O
|
E:THR26
|
2.4
|
0.9
|
1.0
|
|
OD1
|
E:ASP22
|
2.4
|
0.7
|
1.0
|
|
CD
|
E:GLU31
|
2.5
|
0.7
|
1.0
|
|
CG
|
E:ASP20
|
3.1
|
0.6
|
1.0
|
|
CG
|
E:ASP22
|
3.3
|
0.7
|
1.0
|
|
CB
|
E:ASP24
|
3.3
|
0.1
|
1.0
|
|
OD2
|
E:ASP22
|
3.4
|
0.7
|
1.0
|
|
C
|
E:THR26
|
3.5
|
0.9
|
1.0
|
|
OD2
|
E:ASP20
|
3.8
|
0.6
|
1.0
|
|
CA
|
E:ASP20
|
3.9
|
0.6
|
1.0
|
|
CG
|
E:GLU31
|
3.9
|
0.7
|
1.0
|
|
CB
|
E:ASP20
|
3.9
|
0.6
|
1.0
|
|
N
|
E:ASP24
|
4.0
|
0.1
|
1.0
|
|
CA
|
E:ILE27
|
4.2
|
0.2
|
1.0
|
|
CA
|
E:ASP24
|
4.2
|
0.1
|
1.0
|
|
N
|
E:ILE27
|
4.2
|
0.2
|
1.0
|
|
N
|
E:THR28
|
4.4
|
0.8
|
1.0
|
|
CG2
|
E:THR28
|
4.4
|
0.8
|
1.0
|
|
N
|
E:THR26
|
4.5
|
0.9
|
1.0
|
|
C
|
E:ASP20
|
4.6
|
0.6
|
1.0
|
|
CA
|
E:THR26
|
4.6
|
0.9
|
1.0
|
|
OG1
|
E:THR28
|
4.6
|
0.8
|
1.0
|
|
CB
|
E:ASP22
|
4.7
|
0.7
|
1.0
|
|
C
|
E:ILE27
|
4.7
|
0.2
|
1.0
|
|
CB
|
E:GLU31
|
4.7
|
0.7
|
1.0
|
|
N
|
E:ASP22
|
4.7
|
0.7
|
1.0
|
|
CG2
|
E:THR26
|
4.8
|
0.9
|
1.0
|
|
N
|
E:LYS21
|
4.8
|
0.6
|
1.0
|
|
N
|
E:GLY23
|
4.9
|
0.1
|
1.0
|
|
C
|
E:ASP24
|
4.9
|
0.1
|
1.0
|
|
O
|
E:PHE19
|
4.9
|
0.9
|
1.0
|
|
Calcium binding site 2 out
of 12 in 6cno
Go back to
Calcium Binding Sites List in 6cno
Calcium binding site 2 out
of 12 in the Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca202
b:0.9
occ:1.00
|
OD1
|
E:ASP58
|
2.1
|
0.7
|
1.0
|
|
OD1
|
E:ASN60
|
2.3
|
0.8
|
1.0
|
|
OE2
|
E:GLU67
|
2.4
|
0.4
|
1.0
|
|
OE1
|
E:GLU67
|
2.4
|
0.4
|
1.0
|
|
O
|
E:THR62
|
2.4
|
0.8
|
1.0
|
|
OD1
|
E:ASP56
|
2.4
|
0.9
|
1.0
|
|
OD2
|
E:ASP58
|
2.5
|
0.7
|
1.0
|
|
CG
|
E:ASP58
|
2.6
|
0.7
|
1.0
|
|
ND2
|
E:ASN60
|
2.6
|
0.8
|
1.0
|
|
CG
|
E:ASN60
|
2.7
|
0.8
|
1.0
|
|
CD
|
E:GLU67
|
2.7
|
0.4
|
1.0
|
|
CG
|
E:ASP56
|
3.6
|
0.9
|
1.0
|
|
C
|
E:THR62
|
3.6
|
0.8
|
1.0
|
|
CB
|
E:ASN60
|
4.0
|
0.8
|
1.0
|
|
CB
|
E:ASP58
|
4.0
|
0.7
|
1.0
|
|
OD2
|
E:ASP56
|
4.1
|
0.9
|
1.0
|
|
CA
|
E:ILE63
|
4.1
|
0.6
|
1.0
|
|
N
|
E:ASN60
|
4.2
|
0.8
|
1.0
|
|
CG
|
E:GLU67
|
4.2
|
0.4
|
1.0
|
|
N
|
E:ASP58
|
4.3
|
0.7
|
1.0
|
|
N
|
E:ILE63
|
4.3
|
0.6
|
1.0
|
|
N
|
E:THR62
|
4.6
|
0.8
|
1.0
|
|
N
|
E:GLY59
|
4.6
|
0.4
|
1.0
|
|
CA
|
E:ASP58
|
4.6
|
0.7
|
1.0
|
|
CA
|
E:ASN60
|
4.7
|
0.8
|
1.0
|
|
N
|
E:ALA57
|
4.7
|
0.1
|
1.0
|
|
OD1
|
E:ASP64
|
4.7
|
0.0
|
1.0
|
|
CA
|
E:THR62
|
4.7
|
0.8
|
1.0
|
|
CA
|
E:ASP56
|
4.8
|
0.9
|
1.0
|
|
CB
|
E:ASP56
|
4.8
|
0.9
|
1.0
|
|
N
|
E:ASP64
|
4.8
|
0.0
|
1.0
|
|
N
|
E:GLY61
|
4.9
|
0.2
|
1.0
|
|
CG1
|
E:ILE63
|
4.9
|
0.6
|
1.0
|
|
C
|
E:ILE63
|
5.0
|
0.6
|
1.0
|
|
OG1
|
E:THR62
|
5.0
|
0.8
|
1.0
|
|
Calcium binding site 3 out
of 12 in 6cno
Go back to
Calcium Binding Sites List in 6cno
Calcium binding site 3 out
of 12 in the Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca203
b:0.5
occ:1.00
|
ND2
|
E:ASN97
|
2.1
|
0.8
|
1.0
|
|
O
|
E:TYR99
|
2.2
|
0.5
|
1.0
|
|
OD1
|
E:ASN97
|
2.2
|
0.8
|
1.0
|
|
OE2
|
E:GLU104
|
2.3
|
0.5
|
1.0
|
|
OD1
|
E:ASP95
|
2.3
|
0.4
|
1.0
|
|
OE1
|
E:GLU104
|
2.4
|
0.5
|
1.0
|
|
OD1
|
E:ASP93
|
2.4
|
0.8
|
1.0
|
|
CG
|
E:ASN97
|
2.4
|
0.8
|
1.0
|
|
CD
|
E:GLU104
|
2.6
|
0.5
|
1.0
|
|
CG
|
E:ASP95
|
3.1
|
0.4
|
1.0
|
|
C
|
E:TYR99
|
3.2
|
0.5
|
1.0
|
|
OD2
|
E:ASP95
|
3.2
|
0.4
|
1.0
|
|
CG
|
E:ASP93
|
3.4
|
0.8
|
1.0
|
|
CA
|
E:ASP93
|
3.8
|
0.8
|
1.0
|
|
CB
|
E:ASN97
|
3.8
|
0.8
|
1.0
|
|
N
|
E:ILE100
|
4.0
|
0.5
|
1.0
|
|
CA
|
E:ILE100
|
4.0
|
0.5
|
1.0
|
|
CB
|
E:ASP93
|
4.1
|
0.8
|
1.0
|
|
CG
|
E:GLU104
|
4.1
|
0.5
|
1.0
|
|
CA
|
E:TYR99
|
4.1
|
0.5
|
1.0
|
|
N
|
E:TYR99
|
4.1
|
0.5
|
1.0
|
|
OD2
|
E:ASP93
|
4.3
|
0.8
|
1.0
|
|
N
|
E:SER101
|
4.3
|
0.4
|
1.0
|
|
N
|
E:ASN97
|
4.3
|
0.8
|
1.0
|
|
C
|
E:ASP93
|
4.5
|
0.8
|
1.0
|
|
N
|
E:LYS94
|
4.5
|
0.3
|
1.0
|
|
N
|
E:ASP95
|
4.5
|
0.4
|
1.0
|
|
CB
|
E:TYR99
|
4.5
|
0.5
|
1.0
|
|
CB
|
E:ASP95
|
4.5
|
0.4
|
1.0
|
|
C
|
E:ILE100
|
4.6
|
0.5
|
1.0
|
|
CA
|
E:ASN97
|
4.6
|
0.8
|
1.0
|
|
O
|
E:PHE92
|
4.9
|
0.3
|
1.0
|
|
N
|
E:ASP93
|
4.9
|
0.8
|
1.0
|
|
N
|
E:GLY96
|
4.9
|
0.2
|
1.0
|
|
CB
|
E:GLU104
|
5.0
|
0.5
|
1.0
|
|
CA
|
E:ASP95
|
5.0
|
0.4
|
1.0
|
|
Calcium binding site 4 out
of 12 in 6cno
Go back to
Calcium Binding Sites List in 6cno
Calcium binding site 4 out
of 12 in the Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Ca201
b:0.7
occ:1.00
|
OD2
|
F:ASP24
|
1.9
|
0.5
|
1.0
|
|
CG
|
F:ASP24
|
2.1
|
0.5
|
1.0
|
|
OD1
|
F:ASP24
|
2.1
|
0.5
|
1.0
|
|
OE2
|
F:GLU31
|
2.2
|
0.1
|
1.0
|
|
OE1
|
F:GLU31
|
2.3
|
0.1
|
1.0
|
|
OD1
|
F:ASP20
|
2.3
|
0.7
|
1.0
|
|
OD1
|
F:ASP22
|
2.4
|
0.8
|
1.0
|
|
O
|
F:THR26
|
2.4
|
0.0
|
1.0
|
|
CD
|
F:GLU31
|
2.5
|
0.1
|
1.0
|
|
CG
|
F:ASP20
|
3.1
|
0.7
|
1.0
|
|
CG
|
F:ASP22
|
3.3
|
0.8
|
1.0
|
|
CB
|
F:ASP24
|
3.3
|
0.5
|
1.0
|
|
OD2
|
F:ASP22
|
3.4
|
0.8
|
1.0
|
|
C
|
F:THR26
|
3.5
|
0.0
|
1.0
|
|
OD2
|
F:ASP20
|
3.8
|
0.7
|
1.0
|
|
CG
|
F:GLU31
|
3.9
|
0.1
|
1.0
|
|
CA
|
F:ASP20
|
3.9
|
0.7
|
1.0
|
|
N
|
F:ASP24
|
4.0
|
0.5
|
1.0
|
|
CB
|
F:ASP20
|
4.0
|
0.7
|
1.0
|
|
CA
|
F:ILE27
|
4.2
|
0.6
|
1.0
|
|
CA
|
F:ASP24
|
4.2
|
0.5
|
1.0
|
|
N
|
F:ILE27
|
4.3
|
0.6
|
1.0
|
|
N
|
F:THR28
|
4.4
|
0.8
|
1.0
|
|
CG2
|
F:THR28
|
4.4
|
0.8
|
1.0
|
|
N
|
F:THR26
|
4.5
|
0.0
|
1.0
|
|
OG1
|
F:THR28
|
4.6
|
0.8
|
1.0
|
|
CA
|
F:THR26
|
4.6
|
0.0
|
1.0
|
|
C
|
F:ASP20
|
4.6
|
0.7
|
1.0
|
|
CB
|
F:ASP22
|
4.7
|
0.8
|
1.0
|
|
C
|
F:ILE27
|
4.7
|
0.6
|
1.0
|
|
CB
|
F:GLU31
|
4.7
|
0.1
|
1.0
|
|
N
|
F:ASP22
|
4.8
|
0.8
|
1.0
|
|
CG2
|
F:THR26
|
4.8
|
0.0
|
1.0
|
|
N
|
F:LYS21
|
4.8
|
0.1
|
1.0
|
|
N
|
F:GLY23
|
4.9
|
0.3
|
1.0
|
|
C
|
F:ASP24
|
4.9
|
0.5
|
1.0
|
|
O
|
F:PHE19
|
5.0
|
0.2
|
1.0
|
|
Calcium binding site 5 out
of 12 in 6cno
Go back to
Calcium Binding Sites List in 6cno
Calcium binding site 5 out
of 12 in the Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Ca202
b:0.6
occ:1.00
|
OD1
|
F:ASP58
|
2.1
|
0.8
|
1.0
|
|
OD1
|
F:ASN60
|
2.3
|
0.7
|
1.0
|
|
OE2
|
F:GLU67
|
2.3
|
0.7
|
1.0
|
|
OE1
|
F:GLU67
|
2.4
|
0.7
|
1.0
|
|
O
|
F:THR62
|
2.4
|
0.7
|
1.0
|
|
OD1
|
F:ASP56
|
2.5
|
0.4
|
1.0
|
|
OD2
|
F:ASP58
|
2.5
|
0.8
|
1.0
|
|
CG
|
F:ASP58
|
2.6
|
0.8
|
1.0
|
|
ND2
|
F:ASN60
|
2.6
|
0.7
|
1.0
|
|
CG
|
F:ASN60
|
2.7
|
0.7
|
1.0
|
|
CD
|
F:GLU67
|
2.7
|
0.7
|
1.0
|
|
CG
|
F:ASP56
|
3.6
|
0.4
|
1.0
|
|
C
|
F:THR62
|
3.6
|
0.7
|
1.0
|
|
CB
|
F:ASP58
|
4.0
|
0.8
|
1.0
|
|
CB
|
F:ASN60
|
4.0
|
0.7
|
1.0
|
|
OD2
|
F:ASP56
|
4.1
|
0.4
|
1.0
|
|
CA
|
F:ILE63
|
4.1
|
0.1
|
1.0
|
|
CG
|
F:GLU67
|
4.2
|
0.7
|
1.0
|
|
N
|
F:ASN60
|
4.2
|
0.7
|
1.0
|
|
N
|
F:ASP58
|
4.3
|
0.8
|
1.0
|
|
N
|
F:ILE63
|
4.4
|
0.1
|
1.0
|
|
N
|
F:THR62
|
4.6
|
0.7
|
1.0
|
|
N
|
F:GLY59
|
4.6
|
0.1
|
1.0
|
|
CA
|
F:ASP58
|
4.6
|
0.8
|
1.0
|
|
CA
|
F:ASN60
|
4.7
|
0.7
|
1.0
|
|
N
|
F:ALA57
|
4.7
|
0.2
|
1.0
|
|
OD1
|
F:ASP64
|
4.7
|
0.1
|
1.0
|
|
CA
|
F:THR62
|
4.8
|
0.7
|
1.0
|
|
CA
|
F:ASP56
|
4.8
|
0.4
|
1.0
|
|
CB
|
F:ASP56
|
4.8
|
0.4
|
1.0
|
|
N
|
F:ASP64
|
4.8
|
0.1
|
1.0
|
|
N
|
F:GLY61
|
4.9
|
0.1
|
1.0
|
|
CG1
|
F:ILE63
|
4.9
|
0.1
|
1.0
|
|
C
|
F:ILE63
|
5.0
|
0.1
|
1.0
|
|
OG1
|
F:THR62
|
5.0
|
0.7
|
1.0
|
|
Calcium binding site 6 out
of 12 in 6cno
Go back to
Calcium Binding Sites List in 6cno
Calcium binding site 6 out
of 12 in the Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 6 of Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Ca203
b:0.7
occ:1.00
|
ND2
|
F:ASN97
|
2.1
|
0.5
|
1.0
|
|
O
|
F:TYR99
|
2.1
|
0.8
|
1.0
|
|
OD1
|
F:ASN97
|
2.2
|
0.5
|
1.0
|
|
OE2
|
F:GLU104
|
2.3
|
0.2
|
1.0
|
|
OD1
|
F:ASP95
|
2.3
|
0.3
|
1.0
|
|
OE1
|
F:GLU104
|
2.3
|
0.2
|
1.0
|
|
OD1
|
F:ASP93
|
2.4
|
0.8
|
1.0
|
|
CG
|
F:ASN97
|
2.4
|
0.5
|
1.0
|
|
CD
|
F:GLU104
|
2.6
|
0.2
|
1.0
|
|
CG
|
F:ASP95
|
3.1
|
0.3
|
1.0
|
|
C
|
F:TYR99
|
3.2
|
0.8
|
1.0
|
|
OD2
|
F:ASP95
|
3.3
|
0.3
|
1.0
|
|
CG
|
F:ASP93
|
3.4
|
0.8
|
1.0
|
|
CA
|
F:ASP93
|
3.8
|
0.8
|
1.0
|
|
CB
|
F:ASN97
|
3.8
|
0.5
|
1.0
|
|
N
|
F:ILE100
|
4.0
|
0.8
|
1.0
|
|
CA
|
F:ILE100
|
4.0
|
0.8
|
1.0
|
|
CB
|
F:ASP93
|
4.1
|
0.8
|
1.0
|
|
CG
|
F:GLU104
|
4.1
|
0.2
|
1.0
|
|
CA
|
F:TYR99
|
4.1
|
0.8
|
1.0
|
|
N
|
F:TYR99
|
4.1
|
0.8
|
1.0
|
|
N
|
F:SER101
|
4.3
|
0.9
|
1.0
|
|
OD2
|
F:ASP93
|
4.3
|
0.8
|
1.0
|
|
N
|
F:ASN97
|
4.4
|
0.5
|
1.0
|
|
C
|
F:ASP93
|
4.5
|
0.8
|
1.0
|
|
CB
|
F:TYR99
|
4.5
|
0.8
|
1.0
|
|
N
|
F:LYS94
|
4.5
|
0.3
|
1.0
|
|
N
|
F:ASP95
|
4.5
|
0.3
|
1.0
|
|
CB
|
F:ASP95
|
4.5
|
0.3
|
1.0
|
|
C
|
F:ILE100
|
4.6
|
0.8
|
1.0
|
|
CA
|
F:ASN97
|
4.7
|
0.5
|
1.0
|
|
O
|
F:PHE92
|
4.9
|
0.4
|
1.0
|
|
N
|
F:ASP93
|
4.9
|
0.8
|
1.0
|
|
N
|
F:GLY96
|
5.0
|
0.9
|
1.0
|
|
CB
|
F:GLU104
|
5.0
|
0.2
|
1.0
|
|
CA
|
F:ASP95
|
5.0
|
0.3
|
1.0
|
|
Calcium binding site 7 out
of 12 in 6cno
Go back to
Calcium Binding Sites List in 6cno
Calcium binding site 7 out
of 12 in the Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 7 of Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Ca201
b:0.4
occ:1.00
|
OD2
|
G:ASP24
|
2.0
|
0.5
|
1.0
|
|
CG
|
G:ASP24
|
2.1
|
0.5
|
1.0
|
|
OD1
|
G:ASP24
|
2.1
|
0.5
|
1.0
|
|
OE2
|
G:GLU31
|
2.3
|
0.7
|
1.0
|
|
OD1
|
G:ASP20
|
2.3
|
0.8
|
1.0
|
|
OE1
|
G:GLU31
|
2.3
|
0.7
|
1.0
|
|
O
|
G:THR26
|
2.4
|
0.5
|
1.0
|
|
OD1
|
G:ASP22
|
2.4
|
0.1
|
1.0
|
|
CD
|
G:GLU31
|
2.5
|
0.7
|
1.0
|
|
CG
|
G:ASP20
|
3.1
|
0.8
|
1.0
|
|
CG
|
G:ASP22
|
3.3
|
0.1
|
1.0
|
|
CB
|
G:ASP24
|
3.3
|
0.5
|
1.0
|
|
OD2
|
G:ASP22
|
3.4
|
0.1
|
1.0
|
|
C
|
G:THR26
|
3.5
|
0.5
|
1.0
|
|
OD2
|
G:ASP20
|
3.8
|
0.8
|
1.0
|
|
CA
|
G:ASP20
|
3.9
|
0.8
|
1.0
|
|
CG
|
G:GLU31
|
3.9
|
0.7
|
1.0
|
|
CB
|
G:ASP20
|
3.9
|
0.8
|
1.0
|
|
N
|
G:ASP24
|
4.0
|
0.5
|
1.0
|
|
CA
|
G:ILE27
|
4.2
|
0.4
|
1.0
|
|
CA
|
G:ASP24
|
4.2
|
0.5
|
1.0
|
|
N
|
G:ILE27
|
4.2
|
0.4
|
1.0
|
|
N
|
G:THR28
|
4.4
|
0.9
|
1.0
|
|
CG2
|
G:THR28
|
4.4
|
0.9
|
1.0
|
|
N
|
G:THR26
|
4.5
|
0.5
|
1.0
|
|
C
|
G:ASP20
|
4.6
|
0.8
|
1.0
|
|
CA
|
G:THR26
|
4.6
|
0.5
|
1.0
|
|
OG1
|
G:THR28
|
4.6
|
0.9
|
1.0
|
|
C
|
G:ILE27
|
4.7
|
0.4
|
1.0
|
|
CB
|
G:ASP22
|
4.7
|
0.1
|
1.0
|
|
CB
|
G:GLU31
|
4.7
|
0.7
|
1.0
|
|
N
|
G:ASP22
|
4.7
|
0.1
|
1.0
|
|
CG2
|
G:THR26
|
4.8
|
0.5
|
1.0
|
|
N
|
G:LYS21
|
4.8
|
0.6
|
1.0
|
|
N
|
G:GLY23
|
4.9
|
0.2
|
1.0
|
|
C
|
G:ASP24
|
4.9
|
0.5
|
1.0
|
|
O
|
G:PHE19
|
4.9
|
0.5
|
1.0
|
|
Calcium binding site 8 out
of 12 in 6cno
Go back to
Calcium Binding Sites List in 6cno
Calcium binding site 8 out
of 12 in the Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 8 of Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Ca202
b:0.6
occ:1.00
|
OD1
|
G:ASP58
|
2.1
|
0.7
|
1.0
|
|
OD1
|
G:ASN60
|
2.3
|
0.6
|
1.0
|
|
OE2
|
G:GLU67
|
2.3
|
0.7
|
1.0
|
|
OE1
|
G:GLU67
|
2.4
|
0.7
|
1.0
|
|
O
|
G:THR62
|
2.4
|
0.1
|
1.0
|
|
OD1
|
G:ASP56
|
2.4
|
0.2
|
1.0
|
|
OD2
|
G:ASP58
|
2.5
|
0.7
|
1.0
|
|
CG
|
G:ASP58
|
2.6
|
0.7
|
1.0
|
|
ND2
|
G:ASN60
|
2.6
|
0.6
|
1.0
|
|
CG
|
G:ASN60
|
2.7
|
0.6
|
1.0
|
|
CD
|
G:GLU67
|
2.7
|
0.7
|
1.0
|
|
CG
|
G:ASP56
|
3.6
|
0.2
|
1.0
|
|
C
|
G:THR62
|
3.6
|
0.1
|
1.0
|
|
CB
|
G:ASP58
|
4.0
|
0.7
|
1.0
|
|
CB
|
G:ASN60
|
4.0
|
0.6
|
1.0
|
|
OD2
|
G:ASP56
|
4.1
|
0.2
|
1.0
|
|
CA
|
G:ILE63
|
4.1
|
0.7
|
1.0
|
|
N
|
G:ASN60
|
4.2
|
0.6
|
1.0
|
|
CG
|
G:GLU67
|
4.2
|
0.7
|
1.0
|
|
N
|
G:ASP58
|
4.2
|
0.7
|
1.0
|
|
N
|
G:ILE63
|
4.4
|
0.7
|
1.0
|
|
N
|
G:GLY59
|
4.6
|
0.0
|
1.0
|
|
N
|
G:THR62
|
4.6
|
0.1
|
1.0
|
|
CA
|
G:ASP58
|
4.6
|
0.7
|
1.0
|
|
CA
|
G:ASN60
|
4.7
|
0.6
|
1.0
|
|
N
|
G:ALA57
|
4.7
|
1.0
|
1.0
|
|
OD1
|
G:ASP64
|
4.7
|
0.9
|
1.0
|
|
CA
|
G:THR62
|
4.8
|
0.1
|
1.0
|
|
CA
|
G:ASP56
|
4.8
|
0.2
|
1.0
|
|
CB
|
G:ASP56
|
4.8
|
0.2
|
1.0
|
|
N
|
G:ASP64
|
4.8
|
0.9
|
1.0
|
|
N
|
G:GLY61
|
4.9
|
0.2
|
1.0
|
|
CG1
|
G:ILE63
|
5.0
|
0.7
|
1.0
|
|
C
|
G:ILE63
|
5.0
|
0.7
|
1.0
|
|
OG1
|
G:THR62
|
5.0
|
0.1
|
1.0
|
|
Calcium binding site 9 out
of 12 in 6cno
Go back to
Calcium Binding Sites List in 6cno
Calcium binding site 9 out
of 12 in the Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 9 of Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:Ca203
b:0.7
occ:1.00
|
ND2
|
G:ASN97
|
2.1
|
0.9
|
1.0
|
|
O
|
G:TYR99
|
2.2
|
0.0
|
1.0
|
|
OD1
|
G:ASN97
|
2.2
|
0.9
|
1.0
|
|
OE2
|
G:GLU104
|
2.3
|
0.6
|
1.0
|
|
OD1
|
G:ASP95
|
2.3
|
0.5
|
1.0
|
|
OE1
|
G:GLU104
|
2.4
|
0.6
|
1.0
|
|
OD1
|
G:ASP93
|
2.4
|
0.8
|
1.0
|
|
CG
|
G:ASN97
|
2.4
|
0.9
|
1.0
|
|
CD
|
G:GLU104
|
2.6
|
0.6
|
1.0
|
|
CG
|
G:ASP95
|
3.1
|
0.5
|
1.0
|
|
C
|
G:TYR99
|
3.2
|
0.0
|
1.0
|
|
OD2
|
G:ASP95
|
3.2
|
0.5
|
1.0
|
|
CG
|
G:ASP93
|
3.4
|
0.8
|
1.0
|
|
CB
|
G:ASN97
|
3.8
|
0.9
|
1.0
|
|
CA
|
G:ASP93
|
3.8
|
0.8
|
1.0
|
|
N
|
G:ILE100
|
4.0
|
0.6
|
1.0
|
|
CA
|
G:ILE100
|
4.0
|
0.6
|
1.0
|
|
CB
|
G:ASP93
|
4.1
|
0.8
|
1.0
|
|
CG
|
G:GLU104
|
4.1
|
0.6
|
1.0
|
|
CA
|
G:TYR99
|
4.1
|
0.0
|
1.0
|
|
N
|
G:TYR99
|
4.1
|
0.0
|
1.0
|
|
N
|
G:SER101
|
4.3
|
0.1
|
1.0
|
|
OD2
|
G:ASP93
|
4.3
|
0.8
|
1.0
|
|
N
|
G:ASN97
|
4.3
|
0.9
|
1.0
|
|
CB
|
G:TYR99
|
4.5
|
0.0
|
1.0
|
|
C
|
G:ASP93
|
4.5
|
0.8
|
1.0
|
|
N
|
G:LYS94
|
4.5
|
0.8
|
1.0
|
|
N
|
G:ASP95
|
4.5
|
0.5
|
1.0
|
|
CB
|
G:ASP95
|
4.5
|
0.5
|
1.0
|
|
C
|
G:ILE100
|
4.6
|
0.6
|
1.0
|
|
CA
|
G:ASN97
|
4.7
|
0.9
|
1.0
|
|
O
|
G:PHE92
|
4.9
|
0.4
|
1.0
|
|
N
|
G:ASP93
|
4.9
|
0.8
|
1.0
|
|
N
|
G:GLY96
|
5.0
|
0.9
|
1.0
|
|
CB
|
G:GLU104
|
5.0
|
0.6
|
1.0
|
|
CA
|
G:ASP95
|
5.0
|
0.5
|
1.0
|
|
Calcium binding site 10 out
of 12 in 6cno
Go back to
Calcium Binding Sites List in 6cno
Calcium binding site 10 out
of 12 in the Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 10 of Cryo-Em Structure of the Human SK4/Calmodulin Channel Complex in the CA2+ Bound State II within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
H:Ca201
b:0.4
occ:1.00
|
OD2
|
H:ASP24
|
2.0
|
0.6
|
1.0
|
|
CG
|
H:ASP24
|
2.1
|
0.6
|
1.0
|
|
OD1
|
H:ASP24
|
2.1
|
0.6
|
1.0
|
|
OD1
|
H:ASP20
|
2.3
|
0.4
|
1.0
|
|
OE2
|
H:GLU31
|
2.3
|
0.5
|
1.0
|
|
OE1
|
H:GLU31
|
2.3
|
0.5
|
1.0
|
|
O
|
H:THR26
|
2.4
|
0.1
|
1.0
|
|
OD1
|
H:ASP22
|
2.4
|
0.1
|
1.0
|
|
CD
|
H:GLU31
|
2.5
|
0.5
|
1.0
|
|
CG
|
H:ASP20
|
3.1
|
0.4
|
1.0
|
|
CG
|
H:ASP22
|
3.3
|
0.1
|
1.0
|
|
CB
|
H:ASP24
|
3.3
|
0.6
|
1.0
|
|
OD2
|
H:ASP22
|
3.5
|
0.1
|
1.0
|
|
C
|
H:THR26
|
3.5
|
0.1
|
1.0
|
|
OD2
|
H:ASP20
|
3.8
|
0.4
|
1.0
|
|
CA
|
H:ASP20
|
3.9
|
0.4
|
1.0
|
|
CB
|
H:ASP20
|
3.9
|
0.4
|
1.0
|
|
N
|
H:ASP24
|
3.9
|
0.6
|
1.0
|
|
CG
|
H:GLU31
|
3.9
|
0.5
|
1.0
|
|
CA
|
H:ILE27
|
4.2
|
0.3
|
1.0
|
|
CA
|
H:ASP24
|
4.2
|
0.6
|
1.0
|
|
N
|
H:ILE27
|
4.2
|
0.3
|
1.0
|
|
N
|
H:THR28
|
4.4
|
0.1
|
1.0
|
|
N
|
H:THR26
|
4.4
|
0.1
|
1.0
|
|
CG2
|
H:THR28
|
4.5
|
0.1
|
1.0
|
|
C
|
H:ASP20
|
4.6
|
0.4
|
1.0
|
|
CA
|
H:THR26
|
4.6
|
0.1
|
1.0
|
|
OG1
|
H:THR28
|
4.7
|
0.1
|
1.0
|
|
C
|
H:ILE27
|
4.7
|
0.3
|
1.0
|
|
CB
|
H:ASP22
|
4.7
|
0.1
|
1.0
|
|
N
|
H:ASP22
|
4.7
|
0.1
|
1.0
|
|
CB
|
H:GLU31
|
4.8
|
0.5
|
1.0
|
|
CG2
|
H:THR26
|
4.8
|
0.1
|
1.0
|
|
N
|
H:LYS21
|
4.8
|
0.1
|
1.0
|
|
N
|
H:GLY23
|
4.9
|
0.4
|
1.0
|
|
C
|
H:ASP24
|
4.9
|
0.6
|
1.0
|
|
O
|
H:PHE19
|
4.9
|
0.6
|
1.0
|
|
N
|
H:ASP20
|
5.0
|
0.4
|
1.0
|
|
Reference:
C.H.Lee,
R.Mackinnon.
Activation Mechanism of A Human Sk-Calmodulin Channel Complex Elucidated By Cryo-Em Structures. Science V. 360 508 2018.
ISSN: ESSN 1095-9203
PubMed: 29724949
DOI: 10.1126/SCIENCE.AAS9466
Page generated: Wed Jul 9 13:07:30 2025
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