Calcium in PDB 6q2j: Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15
Enzymatic activity of Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15
All present enzymatic activity of Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15:
2.7.10.1;
Calcium Binding Sites:
The binding sites of Calcium atom in the Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15
(pdb code 6q2j). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 8 binding sites of Calcium where determined in the
Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15, PDB code: 6q2j:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Calcium binding site 1 out
of 8 in 6q2j
Go back to
Calcium Binding Sites List in 6q2j
Calcium binding site 1 out
of 8 in the Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca708
b:55.4
occ:1.00
|
OD2
|
E:ASP300
|
2.3
|
51.6
|
1.0
|
|
OD2
|
E:ASP302
|
2.3
|
55.6
|
1.0
|
|
OD1
|
E:ASP266
|
2.4
|
56.8
|
1.0
|
|
OD2
|
E:ASP378
|
2.4
|
56.1
|
1.0
|
|
O
|
E:SER268
|
2.6
|
55.9
|
1.0
|
|
OD2
|
E:ASP266
|
2.6
|
56.8
|
1.0
|
|
OD1
|
E:ASP378
|
2.7
|
56.1
|
1.0
|
|
OD1
|
E:ASP300
|
2.7
|
51.6
|
1.0
|
|
CG
|
E:ASP266
|
2.8
|
56.8
|
1.0
|
|
CG
|
E:ASP378
|
2.9
|
56.1
|
1.0
|
|
CG
|
E:ASP300
|
2.9
|
51.6
|
1.0
|
|
CG
|
E:ASP302
|
3.5
|
55.6
|
1.0
|
|
C
|
E:SER268
|
3.8
|
55.9
|
1.0
|
|
CB
|
E:ASP302
|
4.1
|
55.6
|
1.0
|
|
CB
|
E:ASP378
|
4.3
|
56.1
|
1.0
|
|
CB
|
E:ASP266
|
4.3
|
56.8
|
1.0
|
|
CB
|
E:ASP300
|
4.4
|
51.6
|
1.0
|
|
OD1
|
E:ASP302
|
4.5
|
55.6
|
1.0
|
|
N
|
E:ALA269
|
4.7
|
52.0
|
1.0
|
|
CA
|
E:SER268
|
4.8
|
55.9
|
1.0
|
|
OH
|
E:TYR314
|
4.8
|
59.1
|
1.0
|
|
N
|
E:SER268
|
4.8
|
55.9
|
1.0
|
|
CA
|
E:ALA269
|
4.9
|
52.0
|
1.0
|
|
O
|
E:ASP378
|
4.9
|
56.1
|
1.0
|
|
CD
|
E:PRO270
|
4.9
|
50.4
|
1.0
|
|
CA
|
E:ASP266
|
5.0
|
56.8
|
1.0
|
|
CB
|
E:SER268
|
5.0
|
55.9
|
1.0
|
|
Calcium binding site 2 out
of 8 in 6q2j
Go back to
Calcium Binding Sites List in 6q2j
Calcium binding site 2 out
of 8 in the Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca709
b:59.4
occ:1.00
|
OD1
|
E:ASP267
|
2.3
|
60.2
|
1.0
|
|
OD1
|
E:ASP264
|
2.4
|
56.5
|
1.0
|
|
OE2
|
E:GLU232
|
2.4
|
62.1
|
1.0
|
|
O
|
E:GLU265
|
2.4
|
62.2
|
1.0
|
|
OD1
|
E:ASP302
|
2.4
|
55.6
|
1.0
|
|
CG
|
E:ASP264
|
3.2
|
56.5
|
1.0
|
|
OD2
|
E:ASP264
|
3.2
|
56.5
|
1.0
|
|
CG
|
E:ASP267
|
3.5
|
60.2
|
1.0
|
|
CG
|
E:ASP302
|
3.6
|
55.6
|
1.0
|
|
CD
|
E:GLU232
|
3.6
|
62.1
|
1.0
|
|
C
|
E:GLU265
|
3.6
|
62.2
|
1.0
|
|
OE2
|
E:GLU178
|
3.6
|
59.3
|
1.0
|
|
N
|
E:ASP267
|
3.7
|
60.2
|
1.0
|
|
O
|
E:ALA301
|
3.8
|
56.1
|
1.0
|
|
CA
|
E:ASP302
|
4.0
|
55.6
|
1.0
|
|
OD2
|
E:ASP267
|
4.1
|
60.2
|
1.0
|
|
CB
|
E:ASP302
|
4.2
|
55.6
|
1.0
|
|
NH2
|
E:ARG231
|
4.2
|
59.9
|
1.0
|
|
CA
|
E:ASP266
|
4.3
|
56.8
|
1.0
|
|
N
|
E:GLU265
|
4.3
|
62.2
|
1.0
|
|
N
|
E:ASP266
|
4.4
|
56.8
|
1.0
|
|
OE1
|
E:GLU232
|
4.5
|
62.1
|
1.0
|
|
CG
|
E:GLU232
|
4.5
|
62.1
|
1.0
|
|
OG
|
E:SER268
|
4.5
|
55.9
|
1.0
|
|
C
|
E:ASP266
|
4.5
|
56.8
|
1.0
|
|
CA
|
E:ASP267
|
4.5
|
60.2
|
1.0
|
|
CB
|
E:ASP267
|
4.5
|
60.2
|
1.0
|
|
OD2
|
E:ASP302
|
4.6
|
55.6
|
1.0
|
|
C
|
E:ALA301
|
4.6
|
56.1
|
1.0
|
|
CB
|
E:ASP264
|
4.6
|
56.5
|
1.0
|
|
CD
|
E:GLU178
|
4.6
|
59.3
|
1.0
|
|
CA
|
E:GLU265
|
4.7
|
62.2
|
1.0
|
|
N
|
E:ASP302
|
4.7
|
55.6
|
1.0
|
|
C
|
E:ASP267
|
4.8
|
60.2
|
1.0
|
|
N
|
E:SER268
|
4.9
|
55.9
|
1.0
|
|
NE
|
E:ARG231
|
4.9
|
59.9
|
1.0
|
|
OE1
|
E:GLU178
|
4.9
|
59.3
|
1.0
|
|
CA
|
E:CA710
|
4.9
|
77.3
|
1.0
|
|
CB
|
E:SER268
|
5.0
|
55.9
|
1.0
|
|
Calcium binding site 3 out
of 8 in 6q2j
Go back to
Calcium Binding Sites List in 6q2j
Calcium binding site 3 out
of 8 in the Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca710
b:77.3
occ:1.00
|
OD2
|
E:ASP267
|
2.2
|
60.2
|
1.0
|
|
CD
|
E:GLU178
|
2.3
|
59.3
|
1.0
|
|
OE1
|
E:GLU178
|
2.3
|
59.3
|
1.0
|
|
OE1
|
E:GLU232
|
2.4
|
62.1
|
1.0
|
|
OD1
|
E:ASP230
|
2.4
|
63.3
|
1.0
|
|
OE2
|
E:GLU178
|
2.4
|
59.3
|
1.0
|
|
OD1
|
E:ASN179
|
2.4
|
63.6
|
1.0
|
|
CD
|
E:GLU232
|
3.3
|
62.1
|
1.0
|
|
CG
|
E:GLU178
|
3.3
|
59.3
|
1.0
|
|
CG
|
E:ASP230
|
3.3
|
63.3
|
1.0
|
|
CG
|
E:ASP267
|
3.3
|
60.2
|
1.0
|
|
OE2
|
E:GLU232
|
3.5
|
62.1
|
1.0
|
|
CG
|
E:ASN179
|
3.5
|
63.6
|
1.0
|
|
OD1
|
E:ASP267
|
3.9
|
60.2
|
1.0
|
|
CB
|
E:GLU178
|
3.9
|
59.3
|
1.0
|
|
OD2
|
E:ASP230
|
3.9
|
63.3
|
1.0
|
|
ND2
|
E:ASN179
|
4.0
|
63.6
|
1.0
|
|
CA
|
E:ASP230
|
4.1
|
63.3
|
1.0
|
|
CB
|
E:ASP230
|
4.2
|
63.3
|
1.0
|
|
N
|
E:ARG231
|
4.2
|
59.9
|
1.0
|
|
CB
|
E:ASP267
|
4.5
|
60.2
|
1.0
|
|
C
|
E:ASP230
|
4.6
|
63.3
|
1.0
|
|
CG
|
E:GLU232
|
4.7
|
62.1
|
1.0
|
|
CB
|
E:ASN179
|
4.7
|
63.6
|
1.0
|
|
O
|
E:LEU229
|
4.8
|
63.5
|
1.0
|
|
N
|
E:GLU232
|
4.9
|
62.1
|
1.0
|
|
CA
|
E:CA709
|
4.9
|
59.4
|
1.0
|
|
N
|
E:ASN179
|
5.0
|
63.6
|
1.0
|
|
OD1
|
E:ASP264
|
5.0
|
56.5
|
1.0
|
|
Calcium binding site 4 out
of 8 in 6q2j
Go back to
Calcium Binding Sites List in 6q2j
Calcium binding site 4 out
of 8 in the Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca711
b:41.4
occ:1.00
|
OD1
|
E:ASP567
|
2.3
|
47.0
|
1.0
|
|
O
|
E:THR564
|
2.3
|
45.9
|
1.0
|
|
OE1
|
E:GLU574
|
2.4
|
44.1
|
1.0
|
|
OD2
|
E:ASP584
|
2.4
|
43.4
|
1.0
|
|
OE2
|
E:GLU574
|
2.4
|
44.1
|
1.0
|
|
OD2
|
E:ASP567
|
2.5
|
47.0
|
1.0
|
|
O
|
E:HIS569
|
2.6
|
46.9
|
1.0
|
|
CG
|
E:ASP567
|
2.7
|
47.0
|
1.0
|
|
CD
|
E:GLU574
|
2.7
|
44.1
|
1.0
|
|
O
|
E:CYS565
|
2.8
|
46.6
|
1.0
|
|
C
|
E:THR564
|
3.4
|
45.9
|
1.0
|
|
CG
|
E:ASP584
|
3.5
|
43.4
|
1.0
|
|
C
|
E:CYS565
|
3.6
|
46.6
|
1.0
|
|
CA
|
E:CYS565
|
3.6
|
46.6
|
1.0
|
|
C
|
E:HIS569
|
3.8
|
46.9
|
1.0
|
|
N
|
E:CYS565
|
4.0
|
46.6
|
1.0
|
|
CB
|
E:ASP584
|
4.1
|
43.4
|
1.0
|
|
CB
|
E:ASP567
|
4.2
|
47.0
|
1.0
|
|
OD1
|
E:ASP571
|
4.2
|
44.7
|
1.0
|
|
CG
|
E:GLU574
|
4.3
|
44.1
|
1.0
|
|
CG2
|
E:THR564
|
4.3
|
45.9
|
1.0
|
|
SG
|
E:CYS581
|
4.3
|
39.8
|
1.0
|
|
N
|
E:ASP567
|
4.4
|
47.0
|
1.0
|
|
CA
|
E:THR564
|
4.6
|
45.9
|
1.0
|
|
OD1
|
E:ASP584
|
4.6
|
43.4
|
1.0
|
|
CA
|
E:CYS570
|
4.6
|
46.4
|
1.0
|
|
N
|
E:CYS570
|
4.6
|
46.4
|
1.0
|
|
N
|
E:HIS569
|
4.7
|
46.9
|
1.0
|
|
CA
|
E:HIS569
|
4.8
|
46.9
|
1.0
|
|
N
|
E:PRO566
|
4.8
|
43.2
|
1.0
|
|
N
|
E:ASP571
|
4.8
|
44.7
|
1.0
|
|
CG
|
E:ASP571
|
4.8
|
44.7
|
1.0
|
|
CA
|
E:ASP567
|
4.9
|
47.0
|
1.0
|
|
CB
|
E:CYS565
|
4.9
|
46.6
|
1.0
|
|
Calcium binding site 5 out
of 8 in 6q2j
Go back to
Calcium Binding Sites List in 6q2j
Calcium binding site 5 out
of 8 in the Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Ca708
b:55.4
occ:1.00
|
OD2
|
F:ASP300
|
2.3
|
51.6
|
1.0
|
|
OD2
|
F:ASP302
|
2.3
|
55.6
|
1.0
|
|
OD1
|
F:ASP266
|
2.4
|
56.8
|
1.0
|
|
OD2
|
F:ASP378
|
2.4
|
56.1
|
1.0
|
|
O
|
F:SER268
|
2.6
|
55.9
|
1.0
|
|
OD2
|
F:ASP266
|
2.6
|
56.8
|
1.0
|
|
OD1
|
F:ASP378
|
2.7
|
56.1
|
1.0
|
|
OD1
|
F:ASP300
|
2.7
|
51.6
|
1.0
|
|
CG
|
F:ASP266
|
2.8
|
56.8
|
1.0
|
|
CG
|
F:ASP378
|
2.9
|
56.1
|
1.0
|
|
CG
|
F:ASP300
|
2.9
|
51.6
|
1.0
|
|
CG
|
F:ASP302
|
3.5
|
55.6
|
1.0
|
|
C
|
F:SER268
|
3.8
|
55.9
|
1.0
|
|
CB
|
F:ASP302
|
4.1
|
55.6
|
1.0
|
|
CB
|
F:ASP378
|
4.3
|
56.1
|
1.0
|
|
CB
|
F:ASP266
|
4.3
|
56.8
|
1.0
|
|
CB
|
F:ASP300
|
4.4
|
51.6
|
1.0
|
|
OD1
|
F:ASP302
|
4.5
|
55.6
|
1.0
|
|
N
|
F:ALA269
|
4.7
|
52.0
|
1.0
|
|
OH
|
F:TYR314
|
4.8
|
59.1
|
1.0
|
|
CA
|
F:SER268
|
4.8
|
55.9
|
1.0
|
|
N
|
F:SER268
|
4.8
|
55.9
|
1.0
|
|
CA
|
F:ALA269
|
4.9
|
52.0
|
1.0
|
|
O
|
F:ASP378
|
4.9
|
56.1
|
1.0
|
|
CD
|
F:PRO270
|
4.9
|
50.4
|
1.0
|
|
CA
|
F:ASP266
|
5.0
|
56.8
|
1.0
|
|
CB
|
F:SER268
|
5.0
|
55.9
|
1.0
|
|
Calcium binding site 6 out
of 8 in 6q2j
Go back to
Calcium Binding Sites List in 6q2j
Calcium binding site 6 out
of 8 in the Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 6 of Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Ca709
b:59.4
occ:1.00
|
OD1
|
F:ASP267
|
2.3
|
60.2
|
1.0
|
|
OD1
|
F:ASP264
|
2.4
|
56.5
|
1.0
|
|
OE2
|
F:GLU232
|
2.4
|
62.1
|
1.0
|
|
O
|
F:GLU265
|
2.4
|
62.2
|
1.0
|
|
OD1
|
F:ASP302
|
2.4
|
55.6
|
1.0
|
|
CG
|
F:ASP264
|
3.2
|
56.5
|
1.0
|
|
OD2
|
F:ASP264
|
3.2
|
56.5
|
1.0
|
|
CG
|
F:ASP267
|
3.5
|
60.2
|
1.0
|
|
CG
|
F:ASP302
|
3.6
|
55.6
|
1.0
|
|
CD
|
F:GLU232
|
3.6
|
62.1
|
1.0
|
|
C
|
F:GLU265
|
3.6
|
62.2
|
1.0
|
|
OE2
|
F:GLU178
|
3.6
|
59.3
|
1.0
|
|
N
|
F:ASP267
|
3.7
|
60.2
|
1.0
|
|
O
|
F:ALA301
|
3.8
|
56.1
|
1.0
|
|
CA
|
F:ASP302
|
4.0
|
55.6
|
1.0
|
|
OD2
|
F:ASP267
|
4.1
|
60.2
|
1.0
|
|
CB
|
F:ASP302
|
4.2
|
55.6
|
1.0
|
|
NH2
|
F:ARG231
|
4.2
|
59.9
|
1.0
|
|
CA
|
F:ASP266
|
4.3
|
56.8
|
1.0
|
|
N
|
F:GLU265
|
4.3
|
62.2
|
1.0
|
|
N
|
F:ASP266
|
4.4
|
56.8
|
1.0
|
|
OE1
|
F:GLU232
|
4.5
|
62.1
|
1.0
|
|
CG
|
F:GLU232
|
4.5
|
62.1
|
1.0
|
|
OG
|
F:SER268
|
4.5
|
55.9
|
1.0
|
|
C
|
F:ASP266
|
4.5
|
56.8
|
1.0
|
|
CA
|
F:ASP267
|
4.5
|
60.2
|
1.0
|
|
CB
|
F:ASP267
|
4.5
|
60.2
|
1.0
|
|
OD2
|
F:ASP302
|
4.6
|
55.6
|
1.0
|
|
C
|
F:ALA301
|
4.6
|
56.1
|
1.0
|
|
CB
|
F:ASP264
|
4.6
|
56.5
|
1.0
|
|
CD
|
F:GLU178
|
4.6
|
59.3
|
1.0
|
|
CA
|
F:GLU265
|
4.7
|
62.2
|
1.0
|
|
N
|
F:ASP302
|
4.7
|
55.6
|
1.0
|
|
C
|
F:ASP267
|
4.8
|
60.2
|
1.0
|
|
N
|
F:SER268
|
4.9
|
55.9
|
1.0
|
|
NE
|
F:ARG231
|
4.9
|
59.9
|
1.0
|
|
OE1
|
F:GLU178
|
4.9
|
59.3
|
1.0
|
|
CA
|
F:CA710
|
4.9
|
77.3
|
1.0
|
|
CB
|
F:SER268
|
5.0
|
55.9
|
1.0
|
|
Calcium binding site 7 out
of 8 in 6q2j
Go back to
Calcium Binding Sites List in 6q2j
Calcium binding site 7 out
of 8 in the Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 7 of Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Ca710
b:77.3
occ:1.00
|
OD2
|
F:ASP267
|
2.2
|
60.2
|
1.0
|
|
CD
|
F:GLU178
|
2.3
|
59.3
|
1.0
|
|
OE1
|
F:GLU178
|
2.3
|
59.3
|
1.0
|
|
OE1
|
F:GLU232
|
2.4
|
62.1
|
1.0
|
|
OD1
|
F:ASP230
|
2.4
|
63.3
|
1.0
|
|
OE2
|
F:GLU178
|
2.4
|
59.3
|
1.0
|
|
OD1
|
F:ASN179
|
2.4
|
63.6
|
1.0
|
|
CD
|
F:GLU232
|
3.3
|
62.1
|
1.0
|
|
CG
|
F:GLU178
|
3.3
|
59.3
|
1.0
|
|
CG
|
F:ASP230
|
3.3
|
63.3
|
1.0
|
|
CG
|
F:ASP267
|
3.3
|
60.2
|
1.0
|
|
OE2
|
F:GLU232
|
3.5
|
62.1
|
1.0
|
|
CG
|
F:ASN179
|
3.5
|
63.6
|
1.0
|
|
OD1
|
F:ASP267
|
3.9
|
60.2
|
1.0
|
|
CB
|
F:GLU178
|
3.9
|
59.3
|
1.0
|
|
OD2
|
F:ASP230
|
3.9
|
63.3
|
1.0
|
|
ND2
|
F:ASN179
|
4.0
|
63.6
|
1.0
|
|
CA
|
F:ASP230
|
4.1
|
63.3
|
1.0
|
|
CB
|
F:ASP230
|
4.2
|
63.3
|
1.0
|
|
N
|
F:ARG231
|
4.2
|
59.9
|
1.0
|
|
CB
|
F:ASP267
|
4.5
|
60.2
|
1.0
|
|
C
|
F:ASP230
|
4.6
|
63.3
|
1.0
|
|
CG
|
F:GLU232
|
4.7
|
62.1
|
1.0
|
|
CB
|
F:ASN179
|
4.7
|
63.6
|
1.0
|
|
O
|
F:LEU229
|
4.8
|
63.5
|
1.0
|
|
N
|
F:GLU232
|
4.9
|
62.1
|
1.0
|
|
CA
|
F:CA709
|
4.9
|
59.4
|
1.0
|
|
N
|
F:ASN179
|
5.0
|
63.6
|
1.0
|
|
OD1
|
F:ASP264
|
5.0
|
56.5
|
1.0
|
|
Calcium binding site 8 out
of 8 in 6q2j
Go back to
Calcium Binding Sites List in 6q2j
Calcium binding site 8 out
of 8 in the Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 8 of Cryo-Em Structure of Extracellular Dimeric Complex of Ret/Gfral/GDF15 within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Ca711
b:41.4
occ:1.00
|
OD1
|
F:ASP567
|
2.3
|
47.0
|
1.0
|
|
O
|
F:THR564
|
2.3
|
45.9
|
1.0
|
|
OE1
|
F:GLU574
|
2.4
|
44.1
|
1.0
|
|
OD2
|
F:ASP584
|
2.4
|
43.4
|
1.0
|
|
OE2
|
F:GLU574
|
2.4
|
44.1
|
1.0
|
|
OD2
|
F:ASP567
|
2.5
|
47.0
|
1.0
|
|
O
|
F:HIS569
|
2.6
|
46.9
|
1.0
|
|
CG
|
F:ASP567
|
2.7
|
47.0
|
1.0
|
|
CD
|
F:GLU574
|
2.7
|
44.1
|
1.0
|
|
O
|
F:CYS565
|
2.8
|
46.6
|
1.0
|
|
C
|
F:THR564
|
3.4
|
45.9
|
1.0
|
|
CG
|
F:ASP584
|
3.5
|
43.4
|
1.0
|
|
C
|
F:CYS565
|
3.6
|
46.6
|
1.0
|
|
CA
|
F:CYS565
|
3.6
|
46.6
|
1.0
|
|
C
|
F:HIS569
|
3.8
|
46.9
|
1.0
|
|
N
|
F:CYS565
|
4.0
|
46.6
|
1.0
|
|
CB
|
F:ASP584
|
4.1
|
43.4
|
1.0
|
|
CB
|
F:ASP567
|
4.2
|
47.0
|
1.0
|
|
OD1
|
F:ASP571
|
4.2
|
44.7
|
1.0
|
|
CG
|
F:GLU574
|
4.3
|
44.1
|
1.0
|
|
CG2
|
F:THR564
|
4.3
|
45.9
|
1.0
|
|
SG
|
F:CYS581
|
4.3
|
39.8
|
1.0
|
|
N
|
F:ASP567
|
4.4
|
47.0
|
1.0
|
|
CA
|
F:THR564
|
4.6
|
45.9
|
1.0
|
|
OD1
|
F:ASP584
|
4.6
|
43.4
|
1.0
|
|
CA
|
F:CYS570
|
4.6
|
46.4
|
1.0
|
|
N
|
F:CYS570
|
4.6
|
46.4
|
1.0
|
|
N
|
F:HIS569
|
4.7
|
46.9
|
1.0
|
|
CA
|
F:HIS569
|
4.8
|
46.9
|
1.0
|
|
N
|
F:PRO566
|
4.8
|
43.2
|
1.0
|
|
N
|
F:ASP571
|
4.8
|
44.7
|
1.0
|
|
CG
|
F:ASP571
|
4.8
|
44.7
|
1.0
|
|
CA
|
F:ASP567
|
4.9
|
47.0
|
1.0
|
|
CB
|
F:CYS565
|
4.9
|
46.6
|
1.0
|
|
Reference:
J.Li,
G.Shang,
Y.J.Chen,
C.A.Brautigam,
J.Liou,
X.Zhang,
X.C.Bai.
Cryo-Em Analyses Reveal the Common Mechanism and Diversification in the Activation of Ret By Different Ligands. Elife V. 8 2019.
ISSN: ESSN 2050-084X
PubMed: 31535977
DOI: 10.7554/ELIFE.47650
Page generated: Tue Jul 16 13:10:30 2024
|
