Calcium in PDB 6sl2: Alpha-Actinin From Entamoeba Histolytica

The structure of Alpha-Actinin From Entamoeba Histolytica, PDB code: 6sl2 was solved by N.Pinotsis, M.B.Khan, K.Djinovic-Carugo, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.64 / 3.10
Space group	P 42 21 2
Cell size a, b, c (Å), α, β, γ (°)	192.262, 192.262, 57.168, 90.00, 90.00, 90.00
R / Rfree (%)	21.5 / 25.1

The structure of Alpha-Actinin From Entamoeba Histolytica also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Calcium atom in the Alpha-Actinin From Entamoeba Histolytica (pdb code 6sl2). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Alpha-Actinin From Entamoeba Histolytica, PDB code: 6sl2:

Calcium binding site 1 out of 1 in the Alpha-Actinin From Entamoeba Histolytica


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Alpha-Actinin From Entamoeba Histolytica within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca700 b:85.4 occ:1.00 OD1 A:ASP497 2.4 77.4 1.0 OE1 A:GLU508 2.4 87.1 1.0 O A:ILE503 2.4 63.5 1.0 OD1 A:ASP501 2.5 94.7 1.0 OE2 A:GLU508 2.7 80.5 1.0 OD2 A:ASP501 2.9 94.1 1.0 OD1 A:ASN499 2.9 0.3 1.0 CD A:GLU508 2.9 85.8 1.0 CG A:ASP501 3.0 99.7 1.0 OD1 A:ASP505 3.2 0.9 1.0 O A:ASN499 3.4 0.3 1.0 CG A:ASP497 3.6 81.2 1.0 CG A:ASN499 3.6 0.5 1.0 C A:ILE503 3.7 84.4 1.0 CG A:ASP505 3.9 0.7 1.0 ND2 A:ASN499 3.9 98.5 1.0 OD2 A:ASP505 4.1 0.9 1.0 OD2 A:ASP497 4.2 82.5 1.0 N A:ASP505 4.2 74.3 1.0 CA A:LEU504 4.4 61.7 1.0 CG A:GLU508 4.4 67.7 1.0 N A:LEU504 4.5 61.2 1.0 CB A:ASP501 4.5 68.4 1.0 C A:ASN499 4.5 97.4 1.0 N A:ILE503 4.6 71.6 1.0 C A:LEU504 4.7 69.9 1.0 CA A:ASP497 4.7 81.7 1.0 CA A:ILE503 4.7 73.0 1.0 CB A:ASP497 4.7 63.6 1.0 N A:ASN499 4.7 95.2 1.0 N A:ASP501 4.8 67.7 1.0 CB A:ASN499 4.9 95.5 1.0 N A:GLY498 4.9 68.8 1.0 CB A:ASP505 4.9 69.3 1.0 CA A:ASN499 5.0 95.9 1.0

N.Pinotsis, K.Zielinska, M.Babuta, J.L.Arolas, J.Kostan, M.B.Khan, C.Schreiner, A.Salmazo, L.Ciccarelli, M.Puchinger, E.A.Gkougkoulia, E.A.Ribeiro Jr., T.C.Marlovits, A.Bhattacharya, K.Djinovic-Carugo. Calcium Modulates the Domain Flexibility and Function of An Alpha-Actinin Similar to the Ancestral Alpha-Actinin. Proc.Natl.Acad.Sci.Usa V. 117 22101 2020.
ISSN: ESSN 1091-6490
PubMed: 32848067
DOI: 10.1073/PNAS.1917269117