Calcium in PDB 6tm6: MUC2 CYSD1 Domain

The structure of MUC2 CYSD1 Domain, PDB code: 6tm6 was solved by L.Khmelnitsky, D.Fass, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	15.23 / 1.63
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	54.879, 57.854, 27.471, 90.00, 90.00, 90.00
R / Rfree (%)	17.4 / 21.1

The binding sites of Calcium atom in the MUC2 CYSD1 Domain (pdb code 6tm6). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the MUC2 CYSD1 Domain, PDB code: 6tm6:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the MUC2 CYSD1 Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of MUC2 CYSD1 Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1401 b:17.4 occ:1.00 O A:ASP1312 2.3 17.6 1.0 OD1 A:ASN1310 2.3 20.7 1.0 OD1 A:ASP1381 2.4 18.8 1.0 O A:TYR1382 2.4 17.4 1.0 OE2 A:GLU1324 2.4 18.4 1.0 OD2 A:ASP1322 2.5 17.3 1.0 OD1 A:ASP1322 2.6 18.8 1.0 CG A:ASP1322 2.9 15.3 1.0 C A:ASP1312 3.3 18.8 1.0 CG A:ASN1310 3.5 21.3 1.0 CG A:ASP1381 3.5 18.8 1.0 CD A:GLU1324 3.5 17.9 1.0 C A:TYR1382 3.5 16.7 1.0 N A:TYR1382 3.6 14.6 1.0 OD2 A:ASP1381 4.0 22.1 1.0 CG A:GLU1324 4.1 16.7 1.0 N A:ASP1312 4.1 17.5 1.0 CA A:TYR1382 4.1 15.3 1.0 N A:HIS1313 4.2 18.0 1.0 CA A:ASP1312 4.2 16.9 1.0 ND2 A:ASN1310 4.2 21.0 1.0 CA A:HIS1313 4.2 19.6 1.0 ND1 A:HIS1313 4.3 20.0 1.0 CA A:ASN1310 4.4 19.5 1.0 CB A:ASP1322 4.4 15.4 1.0 C A:ASP1381 4.4 16.4 1.0 CB A:ASN1310 4.5 17.3 1.0 OE1 A:GLU1324 4.5 19.0 1.0 CB A:ASP1312 4.5 15.6 1.0 C A:ASN1310 4.6 17.4 1.0 CA A:ASP1381 4.6 15.8 1.0 N A:LYS1383 4.6 15.7 1.0 CB A:ASP1381 4.7 18.1 1.0 N A:GLU1311 4.7 17.6 1.0 CE1 A:HIS1313 4.8 22.0 1.0 CB A:TYR1382 4.8 14.4 1.0 CG A:HIS1313 4.9 20.4 1.0

Calcium binding site 2 out of 2 in the MUC2 CYSD1 Domain


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of MUC2 CYSD1 Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1402 b:25.4 occ:1.00 O A:SER1316 2.3 22.0 1.0 O A:HIS1313 2.4 18.1 1.0 O A:HOH1541 2.4 18.7 1.0 O A:GLY1321 2.4 16.7 1.0 OD1 A:ASP1319 2.4 19.3 1.0 OD1 A:ASP1312 2.6 19.1 1.0 CG A:ASP1312 3.3 19.8 1.0 OD2 A:ASP1312 3.4 19.4 1.0 C A:SER1316 3.4 23.0 1.0 CG A:ASP1319 3.5 19.3 1.0 C A:HIS1313 3.5 19.1 1.0 C A:GLY1321 3.6 18.3 1.0 OD2 A:ASP1319 3.8 19.6 1.0 N A:SER1316 3.9 24.6 1.0 N A:GLY1321 4.0 14.5 1.0 N A:HIS1313 4.0 18.0 1.0 C A:PRO1314 4.1 21.6 1.0 CA A:PRO1314 4.2 19.0 1.0 CA A:SER1316 4.2 24.3 1.0 O A:PRO1314 4.2 21.9 1.0 N A:PRO1314 4.3 17.8 1.0 CA A:HIS1313 4.4 19.6 1.0 CA A:GLY1321 4.4 17.0 1.0 O A:HOH1561 4.4 34.3 1.0 N A:GLY1317 4.5 23.4 1.0 O A:HOH1549 4.5 23.0 1.0 N A:ASP1322 4.6 15.4 1.0 CA A:GLY1317 4.6 21.0 1.0 N A:SER1315 4.6 20.7 1.0 N A:ASP1320 4.6 15.2 1.0 CA A:ASP1322 4.7 16.8 1.0 CB A:SER1316 4.7 24.7 1.0 CB A:ASP1312 4.7 15.6 1.0 N A:ASP1319 4.7 19.1 1.0 C A:GLY1317 4.8 19.2 1.0 CB A:ASP1319 4.8 19.7 1.0 C A:SER1315 4.9 28.0 1.0 C A:ASP1312 5.0 18.8 1.0

G.Javitt, L.Khmelnitsky, L.Albert, N.Elad, G.Shmul, R.Diskin, D.Fass. Mechanism of Mucin Multimerization To Be Published.