Calcium in PDB 8acf: Structure of the Argx-117 in Complex with A Complement C2 Fragment at Low pH

The structure of Structure of the Argx-117 in Complex with A Complement C2 Fragment at Low pH, PDB code: 8acf was solved by H.G.Olesen, G.R.Andersen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.57 / 1.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	71.83, 89.14, 146.49, 90, 90, 90
R / Rfree (%)	17.8 / 19.9

The structure of Structure of the Argx-117 in Complex with A Complement C2 Fragment at Low pH also contains other interesting chemical elements:

Chlorine

(Cl)

2 atoms

The binding sites of Calcium atom in the Structure of the Argx-117 in Complex with A Complement C2 Fragment at Low pH (pdb code 8acf). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Structure of the Argx-117 in Complex with A Complement C2 Fragment at Low pH, PDB code: 8acf:

Calcium binding site 1 out of 1 in the Structure of the Argx-117 in Complex with A Complement C2 Fragment at Low pH


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of the Argx-117 in Complex with A Complement C2 Fragment at Low pH within 5.0Å range: probe atom residue distance (Å) B Occ H:Ca301 b:33.0 occ:1.00 OD1 H:ASP103 2.2 33.7 1.0 OE1 H:GLU99 2.3 35.2 1.0 O A:ARG103 2.3 31.1 1.0 O H:HOH472 2.4 34.6 1.0 O H:HOH434 2.5 33.5 1.0 OH L:TYR100 2.5 37.0 1.0 HH L:TYR100 2.7 44.5 1.0 CG H:ASP103 3.3 35.1 1.0 HD22 H:ASN33 3.3 44.6 1.0 HB3 H:GLU99 3.4 42.6 1.0 CZ L:TYR100 3.5 38.5 1.0 HD23 A:LEU104 3.5 42.1 1.0 CD H:GLU99 3.5 33.4 1.0 OD2 H:ASP103 3.6 36.5 1.0 C A:ARG103 3.6 29.8 1.0 HA A:LEU104 3.7 39.3 1.0 HB3 A:ARG103 3.7 45.0 1.0 HE2 L:TYR100 3.8 44.7 1.0 HB2 H:GLU99 3.9 42.6 1.0 CB H:GLU99 4.0 35.5 1.0 CE2 L:TYR100 4.0 37.2 1.0 HG2 A:ARG103 4.1 47.6 1.0 ND2 H:ASN33 4.1 37.1 1.0 HA H:ASP103 4.2 38.1 1.0 HB2 H:ASN33 4.2 42.6 1.0 CG H:GLU99 4.3 36.6 1.0 OD1 H:ASP35 4.4 36.3 1.0 HD3 A:ARG103 4.4 51.6 1.0 OD2 H:ASP35 4.4 38.1 1.0 CB A:ARG103 4.4 37.4 1.0 N A:LEU104 4.5 33.2 1.0 CA A:LEU104 4.5 32.7 1.0 CD2 A:LEU104 4.5 35.0 1.0 HD21 H:ASN33 4.5 44.6 1.0 OE2 H:GLU99 4.5 33.6 1.0 CE1 L:TYR100 4.5 40.6 1.0 CA A:ARG103 4.5 37.9 1.0 H A:ARG103 4.6 40.3 1.0 HE1 L:TYR100 4.6 48.8 1.0 CB H:ASP103 4.6 32.2 1.0 O H:HOH443 4.6 46.9 1.0 CG A:ARG103 4.6 39.6 1.0 HD22 A:LEU104 4.7 42.1 1.0 OD2 H:ASP50 4.7 41.3 1.0 O H:HOH442 4.8 34.0 1.0 HG3 H:GLU99 4.8 44.0 1.0 CG H:ASP35 4.8 36.5 1.0 HD21 A:LEU104 4.9 42.1 1.0 CA H:ASP103 4.9 31.7 1.0 N A:ARG103 4.9 33.5 1.0

H.G.Olesen, G.R.Andersen. Structure-Function Analysis of Argx-117, A Calcium- and pH-Dependent Clinical Phase Complement C2 Blocking Antibody To Be Published.