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Calcium in PDB 8si7: Cryo-Em Structure of TRPM7 in Gdn Detergent in Complex with Inhibitor VER155008 in Closed State

Enzymatic activity of Cryo-Em Structure of TRPM7 in Gdn Detergent in Complex with Inhibitor VER155008 in Closed State

All present enzymatic activity of Cryo-Em Structure of TRPM7 in Gdn Detergent in Complex with Inhibitor VER155008 in Closed State:
2.7.11.1;

Other elements in 8si7:

The structure of Cryo-Em Structure of TRPM7 in Gdn Detergent in Complex with Inhibitor VER155008 in Closed State also contains other interesting chemical elements:

Chlorine (Cl) 8 atoms

Calcium Binding Sites:

The binding sites of Calcium atom in the Cryo-Em Structure of TRPM7 in Gdn Detergent in Complex with Inhibitor VER155008 in Closed State (pdb code 8si7). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Cryo-Em Structure of TRPM7 in Gdn Detergent in Complex with Inhibitor VER155008 in Closed State, PDB code: 8si7:

Calcium binding site 1 out of 1 in 8si7

Go back to Calcium Binding Sites List in 8si7
Calcium binding site 1 out of 1 in the Cryo-Em Structure of TRPM7 in Gdn Detergent in Complex with Inhibitor VER155008 in Closed State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Cryo-Em Structure of TRPM7 in Gdn Detergent in Complex with Inhibitor VER155008 in Closed State within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1318

b:132.8
occ:1.00
 HA3 B:GLY1046 3.1 12.3 1.0
HA3 D:GLY1046 3.1 20.3 1.0
HA3 C:GLY1046 3.1 20.9 1.0
HA3 A:GLY1046 3.1 23.6 1.0
HA2 C:GLY1046 3.5 20.9 1.0
HA2 D:GLY1046 3.5 20.3 1.0
HA2 B:GLY1046 3.5 12.3 1.0
HA2 A:GLY1046 3.5 23.6 1.0
CA D:GLY1046 3.7 20.3 1.0
CA B:GLY1046 3.7 12.3 1.0
CA C:GLY1046 3.7 20.9 1.0
CA A:GLY1046 3.8 23.6 1.0
O C:GLY1046 4.1 20.9 1.0
O D:GLY1046 4.1 20.3 1.0
O B:GLY1046 4.1 12.3 1.0
O A:GLY1046 4.1 23.6 1.0
C C:GLY1046 4.4 20.9 1.0
C D:GLY1046 4.4 20.3 1.0
C B:GLY1046 4.4 12.3 1.0
C A:GLY1046 4.4 23.6 1.0
N D:GLY1046 4.8 20.3 1.0
N B:GLY1046 4.8 12.3 1.0
N C:GLY1046 4.8 20.9 1.0
N A:GLY1046 4.9 23.6 1.0

Reference:

K.D.Nadezhdin, L.Correia, C.Narangoda, D.S.Patel, A.Neuberger, T.Gudermann, M.G.Kurnikova, V.Chubanov, A.I.Sobolevsky. Structural Mechanisms of TRPM7 Activation and Inhibition Nat Commun.
ISSN: ESSN 2041-1723
Page generated: Thu Jul 10 07:03:50 2025

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