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Calcium in PDB 8w2l: TRPM7 Structure in Complex with Anticancer Agent CCT128930 in Closed State

Enzymatic activity of TRPM7 Structure in Complex with Anticancer Agent CCT128930 in Closed State

All present enzymatic activity of TRPM7 Structure in Complex with Anticancer Agent CCT128930 in Closed State:
2.7.11.1;

Other elements in 8w2l:

The structure of TRPM7 Structure in Complex with Anticancer Agent CCT128930 in Closed State also contains other interesting chemical elements:

Chlorine (Cl) 4 atoms

Calcium Binding Sites:

The binding sites of Calcium atom in the TRPM7 Structure in Complex with Anticancer Agent CCT128930 in Closed State (pdb code 8w2l). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the TRPM7 Structure in Complex with Anticancer Agent CCT128930 in Closed State, PDB code: 8w2l:

Calcium binding site 1 out of 1 in 8w2l

Go back to Calcium Binding Sites List in 8w2l
Calcium binding site 1 out of 1 in the TRPM7 Structure in Complex with Anticancer Agent CCT128930 in Closed State


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of TRPM7 Structure in Complex with Anticancer Agent CCT128930 in Closed State within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1317

b:56.3
occ:1.00
O A:GLY1046 2.6 27.1 1.0
O C:GLY1046 2.8 24.2 1.0
O D:GLY1046 2.9 22.9 1.0
O B:GLY1046 2.9 23.0 1.0
C A:GLY1046 3.5 27.1 1.0
C C:GLY1046 3.7 24.2 1.0
CA A:GLY1046 3.8 27.1 1.0
C D:GLY1046 3.8 22.9 1.0
C B:GLY1046 3.8 23.0 1.0
CA C:GLY1046 3.8 24.2 1.0
CA D:GLY1046 3.9 22.9 1.0
CA B:GLY1046 3.9 23.0 1.0
O A:HOH1424 4.0 20.9 1.0
O C:HOH1427 4.3 23.2 1.0
O A:HOH1410 4.4 18.3 1.0
O C:HOH1424 4.4 15.9 1.0
N A:GLU1047 4.7 24.2 1.0
N C:GLU1047 4.9 24.6 1.0
N D:GLU1047 5.0 23.6 1.0
N B:GLU1047 5.0 23.7 1.0

Reference:

K.D.Nadezhdin, A.I.Sobolevsky. Structural Basis of Selective TRPM7 Inhibition By the Anticancer Agent CCT128930 To Be Published.
Page generated: Thu Jul 10 08:05:17 2025

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