Calcium in PDB 8wpn: Cryo-Em Structure of the Human TRPC4 in Lipid Nanodiscs

The structure of Cryo-Em Structure of the Human TRPC4 in Lipid Nanodiscs also contains other interesting chemical elements:

Zinc

(Zn)

4 atoms

The binding sites of Calcium atom in the Cryo-Em Structure of the Human TRPC4 in Lipid Nanodiscs (pdb code 8wpn). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Cryo-Em Structure of the Human TRPC4 in Lipid Nanodiscs, PDB code: 8wpn:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Cryo-Em Structure of the Human TRPC4 in Lipid Nanodiscs


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Cryo-Em Structure of the Human TRPC4 in Lipid Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1003 b:76.3 occ:1.00 OE2 A:GLU417 2.4 95.8 1.0 OE1 A:GLN420 2.8 103.0 1.0 OD2 A:ASP438 2.8 72.1 1.0 OD1 A:ASN435 3.3 88.6 1.0 NE2 A:GLN420 3.4 101.9 1.0 CD A:GLN420 3.5 102.2 1.0 CD A:GLU417 3.5 97.3 1.0 CG A:ASN435 3.7 86.8 1.0 NH2 A:ARG491 3.8 62.7 1.0 CG A:ASP438 3.9 72.2 1.0 ND2 A:ASN435 4.0 87.7 1.0 OE1 A:GLU417 4.1 96.2 1.0 CA A:ASN435 4.2 82.2 1.0 CB A:ASP438 4.3 71.3 1.0 CB A:ASN435 4.5 84.3 1.0 CG A:GLU417 4.7 96.6 1.0 N A:ASN435 4.8 81.5 1.0 O A:TRP434 4.9 74.2 1.0 CG A:GLN420 5.0 101.8 1.0

Calcium binding site 2 out of 4 in the Cryo-Em Structure of the Human TRPC4 in Lipid Nanodiscs


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Cryo-Em Structure of the Human TRPC4 in Lipid Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1003 b:76.3 occ:1.00 OE2 B:GLU417 2.4 95.8 1.0 OE1 B:GLN420 2.8 103.0 1.0 OD2 B:ASP438 2.8 72.1 1.0 OD1 B:ASN435 3.3 88.6 1.0 NE2 B:GLN420 3.4 101.9 1.0 CD B:GLN420 3.5 102.2 1.0 CD B:GLU417 3.5 97.3 1.0 CG B:ASN435 3.7 86.8 1.0 NH2 B:ARG491 3.8 62.7 1.0 CG B:ASP438 3.9 72.2 1.0 ND2 B:ASN435 4.0 87.7 1.0 OE1 B:GLU417 4.1 96.2 1.0 CA B:ASN435 4.2 82.2 1.0 CB B:ASP438 4.3 71.3 1.0 CB B:ASN435 4.5 84.3 1.0 CG B:GLU417 4.7 96.6 1.0 N B:ASN435 4.8 81.5 1.0 O B:TRP434 4.9 74.2 1.0 CG B:GLN420 5.0 101.8 1.0

Calcium binding site 3 out of 4 in the Cryo-Em Structure of the Human TRPC4 in Lipid Nanodiscs


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Cryo-Em Structure of the Human TRPC4 in Lipid Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca1003 b:76.3 occ:1.00 OE2 C:GLU417 2.4 95.8 1.0 OE1 C:GLN420 2.8 103.0 1.0 OD2 C:ASP438 2.8 72.1 1.0 OD1 C:ASN435 3.3 88.6 1.0 NE2 C:GLN420 3.4 101.9 1.0 CD C:GLN420 3.5 102.2 1.0 CD C:GLU417 3.5 97.3 1.0 CG C:ASN435 3.7 86.8 1.0 NH2 C:ARG491 3.8 62.7 1.0 CG C:ASP438 3.9 72.2 1.0 ND2 C:ASN435 4.0 87.7 1.0 OE1 C:GLU417 4.1 96.2 1.0 CA C:ASN435 4.2 82.2 1.0 CB C:ASP438 4.3 71.3 1.0 CB C:ASN435 4.5 84.3 1.0 CG C:GLU417 4.7 96.6 1.0 N C:ASN435 4.8 81.5 1.0 O C:TRP434 4.9 74.2 1.0 CG C:GLN420 5.0 101.8 1.0

Calcium binding site 4 out of 4 in the Cryo-Em Structure of the Human TRPC4 in Lipid Nanodiscs


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Cryo-Em Structure of the Human TRPC4 in Lipid Nanodiscs within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca1004 b:76.3 occ:1.00 OE2 D:GLU417 2.4 95.8 1.0 OE1 D:GLN420 2.8 103.0 1.0 OD2 D:ASP438 2.8 72.1 1.0 OD1 D:ASN435 3.3 88.6 1.0 NE2 D:GLN420 3.4 101.9 1.0 CD D:GLN420 3.5 102.2 1.0 CD D:GLU417 3.5 97.3 1.0 CG D:ASN435 3.7 86.8 1.0 NH2 D:ARG491 3.8 62.7 1.0 CG D:ASP438 3.9 72.2 1.0 ND2 D:ASN435 4.0 87.7 1.0 OE1 D:GLU417 4.1 96.2 1.0 CA D:ASN435 4.2 82.2 1.0 CB D:ASP438 4.3 71.3 1.0 CB D:ASN435 4.5 84.3 1.0 CG D:GLU417 4.7 96.6 1.0 N D:ASN435 4.8 81.5 1.0 O D:TRP434 4.9 74.2 1.0 CG D:GLN420 5.0 101.8 1.0

J.Won, H.Jeong, H.H.Lee. Structure of A Trp Channel To Be Published.