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Calcium in PDB 8zic: Structure Complex of 4-Hydroxytryptamine Kinase Psik Complexed with MG2+ and Tryptamine

Enzymatic activity of Structure Complex of 4-Hydroxytryptamine Kinase Psik Complexed with MG2+ and Tryptamine

All present enzymatic activity of Structure Complex of 4-Hydroxytryptamine Kinase Psik Complexed with MG2+ and Tryptamine:
2.7.1.222;

Protein crystallography data

The structure of Structure Complex of 4-Hydroxytryptamine Kinase Psik Complexed with MG2+ and Tryptamine, PDB code: 8zic was solved by C.Y.Meng, Y.Wen, W.T.Guo, B.X.Wu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 60.75 / 2.23
Space group P 42 21 2
Cell size a, b, c (Å), α, β, γ (°) 100.205, 100.205, 76.385, 90, 90, 90
R / Rfree (%) 17 / 21.5

Other elements in 8zic:

The structure of Structure Complex of 4-Hydroxytryptamine Kinase Psik Complexed with MG2+ and Tryptamine also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms

Calcium Binding Sites:

The binding sites of Calcium atom in the Structure Complex of 4-Hydroxytryptamine Kinase Psik Complexed with MG2+ and Tryptamine (pdb code 8zic). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the Structure Complex of 4-Hydroxytryptamine Kinase Psik Complexed with MG2+ and Tryptamine, PDB code: 8zic:

Calcium binding site 1 out of 1 in 8zic

Go back to Calcium Binding Sites List in 8zic
Calcium binding site 1 out of 1 in the Structure Complex of 4-Hydroxytryptamine Kinase Psik Complexed with MG2+ and Tryptamine


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure Complex of 4-Hydroxytryptamine Kinase Psik Complexed with MG2+ and Tryptamine within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca405

b:12.1
occ:1.00
ND1 A:HIS340 2.0 24.9 1.0
CE1 A:HIS340 2.9 29.1 1.0
CG A:HIS340 3.0 27.8 1.0
CB A:HIS340 3.4 29.9 1.0
NE2 A:HIS340 4.1 30.6 1.0
CD2 A:HIS340 4.1 28.9 1.0
CD2 A:LEU201 4.3 31.8 1.0
CA A:HIS340 4.3 28.1 1.0
O A:HIS340 4.8 30.7 1.0
C A:HIS340 5.0 26.9 1.0

Reference:

C.Meng, W.Guo, C.Xiao, Y.Wen, X.Zhu, Q.Zhang, Y.Liang, H.Li, S.Xu, Y.Qiu, H.Chen, W.J.Lin, B.Wu. Structural Basis For Psilocybin Biosynthesis. Nat Commun V. 16 2827 2025.
ISSN: ESSN 2041-1723
PubMed: 40121242
DOI: 10.1038/S41467-025-58239-X
Page generated: Thu Jul 10 08:46:10 2025

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