Calcium in PDB 9asn: Human Drosha and DGCR8 in Complex with Pri-Mir-98

All present enzymatic activity of Human Drosha and DGCR8 in Complex with Pri-Mir-98:
3.1.26.3;

The structure of Human Drosha and DGCR8 in Complex with Pri-Mir-98 also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Calcium atom in the Human Drosha and DGCR8 in Complex with Pri-Mir-98 (pdb code 9asn). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Human Drosha and DGCR8 in Complex with Pri-Mir-98, PDB code: 9asn:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Human Drosha and DGCR8 in Complex with Pri-Mir-98


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human Drosha and DGCR8 in Complex with Pri-Mir-98 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1403 b:30.0 occ:1.00 OE2 A:GLU1147 2.2 141.8 1.0 OP1 E:U22 2.3 159.9 1.0 OE2 A:GLU1222 3.1 141.2 1.0 OD1 A:ASP1219 3.3 148.2 1.0 OE1 A:GLU1222 3.3 141.2 1.0 CD A:GLU1147 3.4 141.8 1.0 CD A:GLU1222 3.6 141.2 1.0 O A:HOH1501 3.7 30.0 1.0 P E:U22 3.7 159.9 1.0 CG A:GLU1147 4.1 141.8 1.0 O5' E:U22 4.2 159.9 1.0 C5' E:U22 4.3 159.9 1.0 CG A:ASP1219 4.3 148.2 1.0 OE1 A:GLU1147 4.4 141.8 1.0 OP2 E:U22 4.6 159.9 1.0 OD2 A:ASP1151 4.8 136.2 1.0 O3' E:G21 4.8 153.4 1.0 OD2 A:ASP1219 4.9 148.2 1.0 OD1 A:ASN1184 4.9 149.4 1.0

Calcium binding site 2 out of 2 in the Human Drosha and DGCR8 in Complex with Pri-Mir-98


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Human Drosha and DGCR8 in Complex with Pri-Mir-98 within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1404 b:30.0 occ:1.00 OD1 A:ASN1042 3.1 127.5 1.0 OE2 A:GLU969 3.2 30.0 1.0 OE1 A:GLU1045 3.7 124.2 1.0 CG A:ASN1042 4.0 127.5 1.0 OP1 E:C101 4.1 149.8 1.0 OE2 A:GLU1045 4.1 124.2 1.0 CD A:GLU969 4.1 30.0 1.0 CD A:GLU1045 4.3 124.2 1.0 ND2 A:ASN1042 4.5 127.5 1.0 CE1 A:HIS1038 4.5 135.3 1.0 C5' E:C101 4.5 149.8 1.0 CG A:GLU969 4.7 30.0 1.0 OD1 A:ASN1006 4.7 129.7 1.0 O5' E:C101 4.9 149.8 1.0 NE2 A:HIS1038 5.0 135.3 1.0 OE1 A:GLU969 5.0 30.0 1.0

A.Garg, L.Joshua-Tor. RNAI_PROTEIN_98 To Be Published.