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Calcium in PDB 9czh: CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent.

Other elements in 9czh:

The structure of CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent. also contains other interesting chemical elements:

Potassium (K) 4 atoms

Calcium Binding Sites:

The binding sites of Calcium atom in the CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent. (pdb code 9czh). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 8 binding sites of Calcium where determined in the CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent., PDB code: 9czh:
Jump to Calcium binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Calcium binding site 1 out of 8 in 9czh

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Calcium binding site 1 out of 8 in the CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent.


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1101

b:86.6
occ:1.00
OE2 A:GLU535 2.4 93.3 1.0
O A:ASN534 2.5 84.8 1.0
O A:ASN509 2.5 77.8 1.0
O A:SER512 2.6 90.7 1.0
O A:VAL532 2.8 87.3 1.0
CD A:GLU535 3.3 88.6 1.0
C A:ASN534 3.5 85.8 1.0
CG A:GLU535 3.5 84.1 1.0
C A:ASN509 3.8 73.7 1.0
C A:SER512 3.8 89.0 1.0
CB A:ARG514 3.9 86.6 1.0
CG A:ARG514 3.9 87.0 1.0
N A:ARG514 4.0 92.8 1.0
C A:VAL532 4.1 80.5 1.0
N A:ASN534 4.2 80.6 1.0
N A:GLU535 4.3 85.4 1.0
C A:SER533 4.4 85.6 1.0
OE1 A:GLU535 4.4 90.0 1.0
CA A:GLU535 4.4 81.2 1.0
CA A:ASN534 4.4 85.3 1.0
CB A:GLU535 4.5 79.5 1.0
CA A:LEU510 4.6 70.1 1.0
CA A:ARG514 4.6 93.3 1.0
C A:LEU510 4.6 74.7 1.0
N A:LEU510 4.6 71.5 1.0
O A:SER533 4.7 87.9 1.0
N A:SER512 4.7 77.6 1.0
CA A:ASN509 4.7 68.7 1.0
C A:MET513 4.7 92.2 1.0
CA A:SER512 4.7 83.8 1.0
N A:MET513 4.8 88.5 1.0
CA A:MET513 4.8 88.7 1.0
CG1 A:VAL532 4.8 75.9 1.0
O A:LEU510 4.9 82.2 1.0
O A:ARG514 4.9 95.1 1.0
CB A:ASN509 4.9 68.5 1.0
CA A:SER533 4.9 84.5 1.0
N A:SER533 5.0 85.4 1.0
CA A:VAL532 5.0 69.6 1.0

Calcium binding site 2 out of 8 in 9czh

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Calcium binding site 2 out of 8 in the CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent.


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca1102

b:94.9
occ:1.00
O A:ASP892 2.4 94.0 1.0
OD2 A:ASP897 2.4 113.5 1.0
OD1 A:ASP895 2.4 106.3 1.0
O A:GLN889 2.5 83.1 1.0
OD1 A:ASP897 2.6 114.5 1.0
OD1 D:ASN449 2.6 102.7 1.0
CG A:ASP897 2.8 113.8 1.0
CG A:ASP895 3.3 106.4 1.0
C A:ASP892 3.5 94.5 1.0
OD2 A:ASP895 3.6 102.3 1.0
CG D:ASN449 3.6 104.3 1.0
C A:GLN889 3.6 80.3 1.0
ND2 D:ASN449 3.8 99.5 1.0
CA A:GLN889 4.2 78.5 1.0
CB A:ASP897 4.3 109.4 1.0
N A:GLN893 4.4 96.4 1.0
CA A:GLN893 4.4 98.3 1.0
O A:ASP895 4.4 112.0 1.0
CA A:ASP892 4.5 88.4 1.0
N A:ASP892 4.5 82.8 1.0
CB A:GLN889 4.6 80.8 1.0
N A:PHE890 4.7 76.9 1.0
CB A:ASP895 4.8 104.2 1.0
C A:ASP895 4.8 111.9 1.0
CB A:ASP892 4.8 91.0 1.0
CA A:PHE890 4.9 69.0 1.0
CB D:ASN449 5.0 96.8 1.0
C A:GLN893 5.0 105.1 1.0

Calcium binding site 3 out of 8 in 9czh

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Calcium binding site 3 out of 8 in the CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent.


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent. within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca1101

b:86.6
occ:1.00
OE2 B:GLU535 2.4 93.3 1.0
O B:ASN534 2.5 84.8 1.0
O B:ASN509 2.5 77.8 1.0
O B:SER512 2.6 90.7 1.0
O B:VAL532 2.8 87.3 1.0
CD B:GLU535 3.3 88.6 1.0
C B:ASN534 3.5 85.8 1.0
CG B:GLU535 3.5 84.1 1.0
C B:ASN509 3.8 73.7 1.0
C B:SER512 3.8 89.0 1.0
CB B:ARG514 3.9 86.6 1.0
CG B:ARG514 3.9 87.0 1.0
N B:ARG514 4.0 92.8 1.0
C B:VAL532 4.1 80.5 1.0
N B:ASN534 4.2 80.6 1.0
N B:GLU535 4.3 85.4 1.0
C B:SER533 4.4 85.6 1.0
OE1 B:GLU535 4.4 90.0 1.0
CA B:GLU535 4.4 81.2 1.0
CA B:ASN534 4.4 85.3 1.0
CB B:GLU535 4.5 79.5 1.0
CA B:LEU510 4.6 70.1 1.0
CA B:ARG514 4.6 93.3 1.0
C B:LEU510 4.6 74.7 1.0
N B:LEU510 4.6 71.5 1.0
O B:SER533 4.7 87.9 1.0
N B:SER512 4.7 77.6 1.0
CA B:ASN509 4.7 68.7 1.0
C B:MET513 4.7 92.2 1.0
CA B:SER512 4.7 83.8 1.0
N B:MET513 4.8 88.5 1.0
CA B:MET513 4.8 88.7 1.0
CG1 B:VAL532 4.8 75.9 1.0
O B:LEU510 4.9 82.2 1.0
O B:ARG514 4.9 95.1 1.0
CB B:ASN509 4.9 68.5 1.0
CA B:SER533 4.9 84.5 1.0
N B:SER533 5.0 85.4 1.0
CA B:VAL532 5.0 69.6 1.0

Calcium binding site 4 out of 8 in 9czh

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Calcium binding site 4 out of 8 in the CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent.


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent. within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Ca1102

b:94.9
occ:1.00
OD2 B:ASP897 2.4 113.5 1.0
O B:ASP892 2.4 94.0 1.0
OD1 B:ASP895 2.4 106.3 1.0
O B:GLN889 2.5 83.1 1.0
OD1 B:ASP897 2.6 114.5 1.0
OD1 A:ASN449 2.6 102.7 1.0
CG B:ASP897 2.8 113.8 1.0
CG B:ASP895 3.3 106.4 1.0
C B:ASP892 3.5 94.5 1.0
OD2 B:ASP895 3.6 102.3 1.0
CG A:ASN449 3.6 104.3 1.0
C B:GLN889 3.6 80.3 1.0
ND2 A:ASN449 3.8 99.5 1.0
CA B:GLN889 4.2 78.5 1.0
CB B:ASP897 4.3 109.4 1.0
N B:GLN893 4.4 96.4 1.0
CA B:GLN893 4.4 98.3 1.0
O B:ASP895 4.4 112.0 1.0
CA B:ASP892 4.5 88.4 1.0
N B:ASP892 4.5 82.8 1.0
CB B:GLN889 4.6 80.8 1.0
N B:PHE890 4.7 76.9 1.0
CB B:ASP895 4.8 104.2 1.0
C B:ASP895 4.8 111.9 1.0
CB B:ASP892 4.8 91.0 1.0
CA B:PHE890 4.9 69.0 1.0
CB A:ASN449 5.0 96.8 1.0

Calcium binding site 5 out of 8 in 9czh

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Calcium binding site 5 out of 8 in the CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent.


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 5 of CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent. within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Ca1101

b:86.6
occ:1.00
OE2 C:GLU535 2.4 93.3 1.0
O C:ASN534 2.5 84.8 1.0
O C:ASN509 2.5 77.8 1.0
O C:SER512 2.6 90.7 1.0
O C:VAL532 2.8 87.3 1.0
CD C:GLU535 3.3 88.6 1.0
C C:ASN534 3.5 85.8 1.0
CG C:GLU535 3.5 84.1 1.0
C C:ASN509 3.8 73.7 1.0
C C:SER512 3.8 89.0 1.0
CB C:ARG514 3.9 86.6 1.0
CG C:ARG514 3.9 87.0 1.0
N C:ARG514 4.0 92.8 1.0
C C:VAL532 4.1 80.5 1.0
N C:ASN534 4.2 80.6 1.0
N C:GLU535 4.3 85.4 1.0
C C:SER533 4.4 85.6 1.0
OE1 C:GLU535 4.4 90.0 1.0
CA C:GLU535 4.4 81.2 1.0
CA C:ASN534 4.4 85.3 1.0
CB C:GLU535 4.5 79.5 1.0
CA C:LEU510 4.6 70.1 1.0
CA C:ARG514 4.6 93.3 1.0
C C:LEU510 4.6 74.7 1.0
N C:LEU510 4.6 71.5 1.0
O C:SER533 4.7 87.9 1.0
N C:SER512 4.7 77.6 1.0
CA C:ASN509 4.7 68.7 1.0
C C:MET513 4.7 92.2 1.0
CA C:SER512 4.7 83.8 1.0
N C:MET513 4.8 88.5 1.0
CA C:MET513 4.8 88.7 1.0
CG1 C:VAL532 4.8 75.9 1.0
O C:LEU510 4.9 82.2 1.0
O C:ARG514 4.9 95.1 1.0
CB C:ASN509 4.9 68.5 1.0
CA C:SER533 4.9 84.5 1.0
N C:SER533 5.0 85.4 1.0
CA C:VAL532 5.0 69.6 1.0

Calcium binding site 6 out of 8 in 9czh

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Calcium binding site 6 out of 8 in the CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent.


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 6 of CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent. within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Ca1102

b:94.9
occ:1.00
OD2 C:ASP897 2.4 113.5 1.0
O C:ASP892 2.4 94.0 1.0
OD1 C:ASP895 2.4 106.3 1.0
O C:GLN889 2.5 83.1 1.0
OD1 C:ASP897 2.6 114.5 1.0
OD1 B:ASN449 2.6 102.7 1.0
CG C:ASP897 2.8 113.8 1.0
CG C:ASP895 3.3 106.4 1.0
C C:ASP892 3.5 94.5 1.0
OD2 C:ASP895 3.6 102.3 1.0
CG B:ASN449 3.6 104.3 1.0
C C:GLN889 3.6 80.3 1.0
ND2 B:ASN449 3.9 99.5 1.0
CA C:GLN889 4.2 78.5 1.0
CB C:ASP897 4.3 109.4 1.0
N C:GLN893 4.4 96.4 1.0
CA C:GLN893 4.4 98.3 1.0
O C:ASP895 4.4 112.0 1.0
CA C:ASP892 4.5 88.4 1.0
N C:ASP892 4.5 82.8 1.0
CB C:GLN889 4.6 80.8 1.0
N C:PHE890 4.7 76.9 1.0
CB C:ASP895 4.8 104.2 1.0
C C:ASP895 4.8 111.9 1.0
CB C:ASP892 4.8 91.0 1.0
CA C:PHE890 4.9 69.0 1.0
CB B:ASN449 5.0 96.8 1.0

Calcium binding site 7 out of 8 in 9czh

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Calcium binding site 7 out of 8 in the CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent.


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 7 of CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent. within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Ca1102

b:86.6
occ:1.00
OE2 D:GLU535 2.4 93.3 1.0
O D:ASN534 2.5 84.8 1.0
O D:ASN509 2.5 77.8 1.0
O D:SER512 2.6 90.7 1.0
O D:VAL532 2.8 87.3 1.0
CD D:GLU535 3.3 88.6 1.0
C D:ASN534 3.5 85.8 1.0
CG D:GLU535 3.5 84.1 1.0
C D:ASN509 3.8 73.7 1.0
C D:SER512 3.8 89.0 1.0
CB D:ARG514 3.9 86.6 1.0
CG D:ARG514 3.9 87.0 1.0
N D:ARG514 4.0 92.8 1.0
C D:VAL532 4.1 80.5 1.0
N D:ASN534 4.2 80.6 1.0
N D:GLU535 4.3 85.4 1.0
C D:SER533 4.4 85.6 1.0
OE1 D:GLU535 4.4 90.0 1.0
CA D:GLU535 4.4 81.2 1.0
CA D:ASN534 4.4 85.3 1.0
CB D:GLU535 4.5 79.5 1.0
CA D:LEU510 4.6 70.1 1.0
CA D:ARG514 4.6 93.3 1.0
C D:LEU510 4.6 74.7 1.0
N D:LEU510 4.6 71.5 1.0
O D:SER533 4.7 87.9 1.0
N D:SER512 4.7 77.6 1.0
CA D:ASN509 4.7 68.7 1.0
C D:MET513 4.7 92.2 1.0
CA D:SER512 4.7 83.8 1.0
N D:MET513 4.8 88.5 1.0
CA D:MET513 4.8 88.7 1.0
CG1 D:VAL532 4.8 75.9 1.0
O D:LEU510 4.9 82.2 1.0
O D:ARG514 4.9 95.1 1.0
CB D:ASN509 4.9 68.5 1.0
CA D:SER533 4.9 84.5 1.0
N D:SER533 5.0 85.4 1.0
CA D:VAL532 5.0 69.6 1.0

Calcium binding site 8 out of 8 in 9czh

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Calcium binding site 8 out of 8 in the CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent.


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 8 of CA2+ Bound Intermediate State of HSLO1 + BETA2N-BETA4 Channel in Detergent. within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Ca1103

b:94.9
occ:1.00
OD2 D:ASP897 2.4 113.5 1.0
O D:ASP892 2.4 94.0 1.0
OD1 D:ASP895 2.4 106.3 1.0
O D:GLN889 2.5 83.1 1.0
OD1 D:ASP897 2.6 114.5 1.0
OD1 C:ASN449 2.6 102.7 1.0
CG D:ASP897 2.8 113.8 1.0
CG D:ASP895 3.3 106.4 1.0
C D:ASP892 3.5 94.5 1.0
OD2 D:ASP895 3.6 102.3 1.0
CG C:ASN449 3.6 104.3 1.0
C D:GLN889 3.6 80.3 1.0
ND2 C:ASN449 3.8 99.5 1.0
CA D:GLN889 4.2 78.5 1.0
CB D:ASP897 4.3 109.4 1.0
N D:GLN893 4.4 96.4 1.0
CA D:GLN893 4.4 98.3 1.0
O D:ASP895 4.4 112.0 1.0
CA D:ASP892 4.5 88.4 1.0
N D:ASP892 4.5 82.8 1.0
CB D:GLN889 4.6 80.8 1.0
N D:PHE890 4.7 76.9 1.0
CB D:ASP895 4.8 104.2 1.0
C D:ASP895 4.8 111.9 1.0
CB D:ASP892 4.8 91.0 1.0
CA D:PHE890 4.9 69.0 1.0
CB C:ASN449 5.0 96.8 1.0

Reference:

S.Agarwal, E.D.Kim, S.Lee, A.Simon, A.Accardi, C.M.Nimigean. Ball-and-Chain Inactivation of A Human Large Conductance Calcium-Activated Potassium Channel. Nat Commun V. 16 1769 2025.
ISSN: ESSN 2041-1723
PubMed: 39971906
DOI: 10.1038/S41467-025-56844-4
Page generated: Thu Jul 10 09:11:30 2025

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