Calcium in PDB 9ic0: Chimeric Mitochondrial Dna Polymerase Gamma Ternary Complex (Mahb) in Mouse-Like Error-Editing Conformer (Composite)

All present enzymatic activity of Chimeric Mitochondrial Dna Polymerase Gamma Ternary Complex (Mahb) in Mouse-Like Error-Editing Conformer (Composite):
2.7.7.7;

The binding sites of Calcium atom in the Chimeric Mitochondrial Dna Polymerase Gamma Ternary Complex (Mahb) in Mouse-Like Error-Editing Conformer (Composite) (pdb code 9ic0). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Chimeric Mitochondrial Dna Polymerase Gamma Ternary Complex (Mahb) in Mouse-Like Error-Editing Conformer (Composite), PDB code: 9ic0:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Chimeric Mitochondrial Dna Polymerase Gamma Ternary Complex (Mahb) in Mouse-Like Error-Editing Conformer (Composite)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Chimeric Mitochondrial Dna Polymerase Gamma Ternary Complex (Mahb) in Mouse-Like Error-Editing Conformer (Composite) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1300 b:101.3 occ:1.00 OD2 A:ASP1113 2.3 71.6 1.0 O1B A:DCP1301 2.3 96.0 1.0 O3A A:DCP1301 2.4 96.0 1.0 PB A:DCP1301 2.7 96.0 1.0 O2B A:DCP1301 3.2 96.0 1.0 CG A:ASP1113 3.4 71.6 1.0 O A:VAL869 3.5 62.1 1.0 OD2 A:ASP868 3.5 62.3 1.0 OD1 A:ASP868 3.8 62.3 1.0 PA A:DCP1301 3.9 96.0 1.0 OD1 A:ASP1113 3.9 71.6 1.0 C5' A:DCP1301 4.0 96.0 1.0 O3' A:DCP1301 4.1 96.0 1.0 CG A:ASP868 4.1 62.3 1.0 N A:SER871 4.2 69.7 1.0 O3B A:DCP1301 4.3 96.0 1.0 O5' A:DCP1301 4.3 96.0 1.0 C3' A:DCP1301 4.5 96.0 1.0 O1A A:DCP1301 4.6 96.0 1.0 CB A:ASP1113 4.6 71.6 1.0 C A:VAL869 4.7 62.1 1.0 C4' A:DCP1301 4.8 96.0 1.0 CA A:SER871 4.9 69.7 1.0 O2A A:DCP1301 4.9 96.0 1.0

Calcium binding site 2 out of 2 in the Chimeric Mitochondrial Dna Polymerase Gamma Ternary Complex (Mahb) in Mouse-Like Error-Editing Conformer (Composite)


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Chimeric Mitochondrial Dna Polymerase Gamma Ternary Complex (Mahb) in Mouse-Like Error-Editing Conformer (Composite) within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1302 b:71.0 occ:1.00 OD1 A:ASP257 2.4 62.2 1.0 OD2 A:ASP257 2.7 62.2 1.0 O A:HIS252 2.8 67.0 1.0 OP1 P:DT25 2.9 95.3 1.0 CG A:ASP257 2.9 62.2 1.0 OD1 A:ASP181 3.4 63.8 1.0 C A:HIS252 4.0 67.0 1.0 P P:DT25 4.0 95.3 1.0 O A:ASN253 4.2 70.0 1.0 CG A:ASP181 4.2 63.8 1.0 CB A:ASP257 4.4 62.2 1.0 O3' P:DC24 4.4 102.3 1.0 OP2 P:DT25 4.4 95.3 1.0 N A:HIS252 4.5 67.0 1.0 C A:ASN253 4.6 70.0 1.0 O A:PHE180 4.7 56.6 1.0 CA A:ASP181 4.7 63.8 1.0 CA A:HIS252 4.7 67.0 1.0 CB A:ASP181 4.8 63.8 1.0 N A:ASP257 4.9 62.2 1.0 C4' P:DC24 4.9 102.3 1.0 CB A:HIS252 5.0 67.0 1.0 N A:ASN253 5.0 70.0 1.0

S.Corra, A.Zuppardo, S.Valenzuela, L.Jenninger, R.Cerutti, S.Sillamaa, E.Hoberg, K.A.S.Johansson, U.Rovsnik, S.Volta, P.Silva-Pinheiro, H.Davis, A.Trifunovic, M.Minczuk, C.M.Gustafsson, A.Suomalainen, M.Zeviani, B.Macao, X.Zhu, M.Falkenberg, C.Viscomi. Modelling Polg Mutations in Mice Unravels A Critical Role of Pol Gamma Beta in Regulating Phenotypic Severity. Nat Commun V. 16 4782 2025.
ISSN: ESSN 2041-1723
PubMed: 40404629
DOI: 10.1038/S41467-025-60059-Y