Calcium »
PDB 4gzt-4h82 »
4h76 »
Calcium in PDB 4h76: Crystal Structure of the Catalytic Domain of Human MMP12 in Complex with A Broad Spectrum Hydroxamate Inhibitor
Enzymatic activity of Crystal Structure of the Catalytic Domain of Human MMP12 in Complex with A Broad Spectrum Hydroxamate Inhibitor
All present enzymatic activity of Crystal Structure of the Catalytic Domain of Human MMP12 in Complex with A Broad Spectrum Hydroxamate Inhibitor:
3.4.24.65;
3.4.24.65;
Protein crystallography data
The structure of Crystal Structure of the Catalytic Domain of Human MMP12 in Complex with A Broad Spectrum Hydroxamate Inhibitor, PDB code: 4h76
was solved by
E.A.Stura,
L.Vera,
E.Cassar-Lajeunesse,
E.Nuti,
V.Dive,
A.Rossello,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 46.76 / 1.50 |
| Space group | P 21 21 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 69.920, 62.890, 37.700, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 16.5 / 18.8 |
Other elements in 4h76:
The structure of Crystal Structure of the Catalytic Domain of Human MMP12 in Complex with A Broad Spectrum Hydroxamate Inhibitor also contains other interesting chemical elements:
| Zinc | (Zn) | 2 atoms |
Calcium Binding Sites:
The binding sites of Calcium atom in the Crystal Structure of the Catalytic Domain of Human MMP12 in Complex with A Broad Spectrum Hydroxamate Inhibitor
(pdb code 4h76). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 3 binding sites of Calcium where determined in the Crystal Structure of the Catalytic Domain of Human MMP12 in Complex with A Broad Spectrum Hydroxamate Inhibitor, PDB code: 4h76:
Jump to Calcium binding site number: 1; 2; 3;
In total 3 binding sites of Calcium where determined in the Crystal Structure of the Catalytic Domain of Human MMP12 in Complex with A Broad Spectrum Hydroxamate Inhibitor, PDB code: 4h76:
Jump to Calcium binding site number: 1; 2; 3;
Calcium binding site 1 out of 3 in 4h76
Go back to
Calcium Binding Sites List in 4h76
Calcium binding site 1 out
of 3 in the Crystal Structure of the Catalytic Domain of Human MMP12 in Complex with A Broad Spectrum Hydroxamate Inhibitor
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Crystal Structure of the Catalytic Domain of Human MMP12 in Complex with A Broad Spectrum Hydroxamate Inhibitor within 5.0Å range:
|
Calcium binding site 2 out of 3 in 4h76
Go back to
Calcium Binding Sites List in 4h76
Calcium binding site 2 out
of 3 in the Crystal Structure of the Catalytic Domain of Human MMP12 in Complex with A Broad Spectrum Hydroxamate Inhibitor
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of Crystal Structure of the Catalytic Domain of Human MMP12 in Complex with A Broad Spectrum Hydroxamate Inhibitor within 5.0Å range:
|
Calcium binding site 3 out of 3 in 4h76
Go back to
Calcium Binding Sites List in 4h76
Calcium binding site 3 out
of 3 in the Crystal Structure of the Catalytic Domain of Human MMP12 in Complex with A Broad Spectrum Hydroxamate Inhibitor
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of Crystal Structure of the Catalytic Domain of Human MMP12 in Complex with A Broad Spectrum Hydroxamate Inhibitor within 5.0Å range:
|
Reference:
C.Antoni,
L.Vera,
L.Devel,
M.P.Catalani,
B.Czarny,
E.Cassar-Lajeunesse,
E.Nuti,
A.Rossello,
V.Dive,
E.A.Stura.
Crystallization of Bi-Functional Ligand Protein Complexes. J.Struct.Biol. V. 182 246 2013.
ISSN: ISSN 1047-8477
PubMed: 23567804
DOI: 10.1016/J.JSB.2013.03.015
Page generated: Sun Jul 14 07:40:24 2024
ISSN: ISSN 1047-8477
PubMed: 23567804
DOI: 10.1016/J.JSB.2013.03.015
Last articles
Ca in 3I6NCa in 3I77
Ca in 3I5E
Ca in 3I5I
Ca in 3I5H
Ca in 3I5G
Ca in 3I57
Ca in 3I08
Ca in 3I46
Ca in 3I4P
