Calcium in PDB 6co7: Structure of the NVTRPM2 Channel in Complex with CA2+

The structure of Structure of the NVTRPM2 Channel in Complex with CA2+ also contains other interesting chemical elements:

Sodium

(Na)

3 atoms

The binding sites of Calcium atom in the Structure of the NVTRPM2 Channel in Complex with CA2+ (pdb code 6co7). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Structure of the NVTRPM2 Channel in Complex with CA2+, PDB code: 6co7:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Structure of the NVTRPM2 Channel in Complex with CA2+


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Structure of the NVTRPM2 Channel in Complex with CA2+ within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca4000 b:42.6 occ:1.00 OD2 A:ASP921 2.5 0.7 1.0 OD1 A:ASN918 2.6 0.5 1.0 OE1 A:GLN896 2.6 0.3 1.0 OE1 A:GLU893 2.7 0.0 1.0 OE2 A:GLU893 2.8 0.8 1.0 CD A:GLU893 3.1 1.0 1.0 CG A:ASP921 3.6 0.8 1.0 CD A:GLN896 3.7 0.9 1.0 CG A:ASN918 3.8 0.7 1.0 NH1 A:ARG960 3.8 0.6 1.0 NE2 A:GLN896 4.1 0.4 1.0 OD1 A:ASP921 4.3 1.0 1.0 CB A:ASP921 4.4 0.4 1.0 ND2 A:ASN918 4.6 0.6 1.0 OH A:TYR912 4.6 0.4 1.0 CG A:GLU893 4.6 0.6 1.0 CA A:ASN918 4.8 0.6 1.0 CB A:ASN918 4.9 0.5 1.0 CZ A:ARG960 4.9 0.5 1.0 CG A:GLN896 5.0 0.2 1.0

Calcium binding site 2 out of 4 in the Structure of the NVTRPM2 Channel in Complex with CA2+


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Structure of the NVTRPM2 Channel in Complex with CA2+ within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca4000 b:42.6 occ:1.00 OD2 B:ASP921 2.5 0.7 1.0 OD1 B:ASN918 2.6 0.5 1.0 OE1 B:GLN896 2.6 0.3 1.0 OE1 B:GLU893 2.7 0.0 1.0 OE2 B:GLU893 2.8 0.8 1.0 CD B:GLU893 3.1 1.0 1.0 CG B:ASP921 3.6 0.8 1.0 CD B:GLN896 3.7 0.9 1.0 CG B:ASN918 3.8 0.7 1.0 NH1 B:ARG960 3.8 0.6 1.0 NE2 B:GLN896 4.1 0.4 1.0 OD1 B:ASP921 4.3 1.0 1.0 CB B:ASP921 4.4 0.4 1.0 ND2 B:ASN918 4.6 0.6 1.0 OH B:TYR912 4.6 0.4 1.0 CG B:GLU893 4.6 0.6 1.0 CA B:ASN918 4.8 0.6 1.0 CB B:ASN918 4.9 0.5 1.0 CZ B:ARG960 4.9 0.5 1.0 CG B:GLN896 5.0 0.2 1.0

Calcium binding site 3 out of 4 in the Structure of the NVTRPM2 Channel in Complex with CA2+


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Structure of the NVTRPM2 Channel in Complex with CA2+ within 5.0Å range: probe atom residue distance (Å) B Occ C:Ca4000 b:42.6 occ:1.00 OD2 C:ASP921 2.5 0.7 1.0 OD1 C:ASN918 2.6 0.5 1.0 OE1 C:GLN896 2.6 0.3 1.0 OE1 C:GLU893 2.7 0.0 1.0 OE2 C:GLU893 2.8 0.8 1.0 CD C:GLU893 3.1 1.0 1.0 CG C:ASP921 3.6 0.8 1.0 CD C:GLN896 3.7 0.9 1.0 CG C:ASN918 3.8 0.7 1.0 NH1 C:ARG960 3.8 0.6 1.0 NE2 C:GLN896 4.1 0.4 1.0 OD1 C:ASP921 4.3 1.0 1.0 CB C:ASP921 4.4 0.4 1.0 ND2 C:ASN918 4.6 0.6 1.0 OH C:TYR912 4.6 0.4 1.0 CG C:GLU893 4.6 0.6 1.0 CA C:ASN918 4.8 0.6 1.0 CB C:ASN918 4.9 0.5 1.0 CZ C:ARG960 4.9 0.5 1.0 CG C:GLN896 5.0 0.2 1.0

Calcium binding site 4 out of 4 in the Structure of the NVTRPM2 Channel in Complex with CA2+


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Structure of the NVTRPM2 Channel in Complex with CA2+ within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca4000 b:42.6 occ:1.00 OD2 D:ASP921 2.5 0.7 1.0 OD1 D:ASN918 2.6 0.5 1.0 OE1 D:GLN896 2.6 0.3 1.0 OE1 D:GLU893 2.7 0.0 1.0 OE2 D:GLU893 2.8 0.8 1.0 CD D:GLU893 3.1 1.0 1.0 CG D:ASP921 3.6 0.8 1.0 CD D:GLN896 3.7 0.9 1.0 CG D:ASN918 3.8 0.7 1.0 NH1 D:ARG960 3.8 0.6 1.0 NE2 D:GLN896 4.1 0.4 1.0 OD1 D:ASP921 4.3 1.0 1.0 CB D:ASP921 4.4 0.4 1.0 ND2 D:ASN918 4.6 0.6 1.0 OH D:TYR912 4.6 0.4 1.0 CG D:GLU893 4.6 0.6 1.0 CA D:ASN918 4.8 0.6 1.0 CB D:ASN918 4.9 0.5 1.0 CZ D:ARG960 4.9 0.5 1.0 CG D:GLN896 5.0 0.2 1.0

Z.Zhang, B.Toth, A.Szollosi, J.Chen, L.Csanady. Structure of A TRPM2 Channel in Complex with CA2+Explains Unique Gating Regulation. Elife V. 7 2018.
ISSN: ESSN 2050-084X
PubMed: 29745897
DOI: 10.7554/ELIFE.36409