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Calcium in PDB 6qbs: The Alkyne Moiety As A Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin KEnzymatic activity of The Alkyne Moiety As A Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K
All present enzymatic activity of The Alkyne Moiety As A Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K:
3.4.22.38; Protein crystallography data
The structure of The Alkyne Moiety As A Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K, PDB code: 6qbs
was solved by
E.Mons,
I.D.C.Jansen,
J.Loboda,
B.R.Van Doodewaerd,
M.Verdoes,
C.A.A.Vanboeckel,
P.A.Van Veelen,
B.Turk,
D.Turk,
J.Hermans,
H.Ovaa,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6qbs:
The structure of The Alkyne Moiety As A Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K also contains other interesting chemical elements:
Calcium Binding Sites:
The binding sites of Calcium atom in the The Alkyne Moiety As A Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K
(pdb code 6qbs). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total only one binding site of Calcium was determined in the The Alkyne Moiety As A Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K, PDB code: 6qbs: Calcium binding site 1 out of 1 in 6qbsGo back to![]() ![]()
Calcium binding site 1 out
of 1 in the The Alkyne Moiety As A Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K
![]() Mono view ![]() Stereo pair view
Reference:
E.Mons,
I.D.C.Jansen,
J.Loboda,
B.R.Van Doodewaerd,
J.Hermans,
M.Verdoes,
C.A.A.Van Boeckel,
P.A.Van Veelen,
B.Turk,
D.Turk,
H.Ovaa.
The Alkyne Moiety As A Latent Electrophile in Irreversible Covalent Small Molecule Inhibitors of Cathepsin K. J. Am. Chem. Soc. V. 141 3507 2019.
Page generated: Sat Dec 12 07:27:09 2020
ISSN: ESSN 1520-5126 PubMed: 30689386 DOI: 10.1021/JACS.8B11027 |
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