Calcium in PDB 7dtv: Human Calcium-Sensing Receptor Bound with L-Trp and Calcium Ions

The binding sites of Calcium atom in the Human Calcium-Sensing Receptor Bound with L-Trp and Calcium Ions (pdb code 7dtv). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Human Calcium-Sensing Receptor Bound with L-Trp and Calcium Ions, PDB code: 7dtv:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Human Calcium-Sensing Receptor Bound with L-Trp and Calcium Ions


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Human Calcium-Sensing Receptor Bound with L-Trp and Calcium Ions within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1102 b:59.3 occ:1.00 OG A:SER302 3.0 29.1 1.0 NH1 A:ARG66 3.8 19.2 1.0 N A:SER303 3.9 34.6 1.0 CA A:SER302 4.0 29.1 1.0 CB A:SER302 4.0 29.1 1.0 CH2 A:TRP1101 4.1 17.7 1.0 CZ A:PHE42 4.2 27.1 1.0 CE1 A:PHE42 4.4 27.1 1.0 C A:SER302 4.5 29.1 1.0 CD A:ARG66 4.5 19.2 1.0 OG A:SER303 4.7 34.6 1.0 O A:SER301 4.8 22.4 1.0 OD1 A:ASN64 4.8 24.4 1.0 CZ3 A:TRP1101 4.9 17.7 1.0 CZ2 A:TRP1101 5.0 17.7 1.0 CZ A:ARG66 5.0 19.2 1.0 CA A:SER303 5.0 34.6 1.0

Calcium binding site 2 out of 4 in the Human Calcium-Sensing Receptor Bound with L-Trp and Calcium Ions


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Human Calcium-Sensing Receptor Bound with L-Trp and Calcium Ions within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1103 b:72.5 occ:1.00 O B:GLY557 3.0 98.0 1.0 OD1 A:ASP234 3.3 43.2 1.0 C B:GLY557 3.6 98.0 1.0 CA B:GLY557 3.7 98.0 1.0 OD2 A:ASP234 3.8 43.2 1.0 CG A:ASP234 3.8 43.2 1.0 O A:GLU231 4.3 38.4 1.0 N B:GLU558 4.6 95.4 1.0

Calcium binding site 3 out of 4 in the Human Calcium-Sensing Receptor Bound with L-Trp and Calcium Ions


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Human Calcium-Sensing Receptor Bound with L-Trp and Calcium Ions within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca1108 b:72.5 occ:1.00 O A:GLY557 3.0 98.0 1.0 OD1 B:ASP234 3.3 43.2 1.0 C A:GLY557 3.6 98.0 1.0 CA A:GLY557 3.7 98.0 1.0 OD2 B:ASP234 3.8 43.2 1.0 CG B:ASP234 3.8 43.2 1.0 O B:GLU231 4.3 38.4 1.0 N A:GLU558 4.6 95.4 1.0

Calcium binding site 4 out of 4 in the Human Calcium-Sensing Receptor Bound with L-Trp and Calcium Ions


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Human Calcium-Sensing Receptor Bound with L-Trp and Calcium Ions within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca1102 b:59.3 occ:1.00 OG B:SER302 3.0 29.1 1.0 NH1 B:ARG66 3.8 19.2 1.0 N B:SER303 3.9 34.6 1.0 CA B:SER302 4.0 29.1 1.0 CB B:SER302 4.0 29.1 1.0 CH2 B:TRP1101 4.1 17.7 1.0 CZ B:PHE42 4.2 27.1 1.0 CE1 B:PHE42 4.4 27.1 1.0 C B:SER302 4.5 29.1 1.0 CD B:ARG66 4.5 19.2 1.0 OG B:SER303 4.7 34.6 1.0 O B:SER301 4.8 22.4 1.0 OD1 B:ASN64 4.8 24.4 1.0 CZ3 B:TRP1101 4.9 17.7 1.0 CZ2 B:TRP1101 5.0 17.7 1.0 CZ B:ARG66 5.0 19.2 1.0 CA B:SER303 5.0 34.6 1.0

S.Ling, P.Shi, S.Liu, X.Meng, Y.Zhou, W.Sun, S.Chang, X.Zhang, L.Zhang, C.Shi, D.Sun, L.Liu, C.Tian. Structural Mechanism of Cooperative Activation of the Human Calcium-Sensing Receptor By Ca 2+ Ions and L-Tryptophan. Cell Res. 2021.
ISSN: ISSN 1001-0602
PubMed: 33603117
DOI: 10.1038/S41422-021-00474-0