Calcium in PDB 7pxg: Verruculogen-Bound Drosophila Slo Channel
Other elements in 7pxg:
The structure of Verruculogen-Bound Drosophila Slo Channel also contains other interesting chemical elements:
Calcium Binding Sites:
The binding sites of Calcium atom in the Verruculogen-Bound Drosophila Slo Channel
(pdb code 7pxg). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 8 binding sites of Calcium where determined in the
Verruculogen-Bound Drosophila Slo Channel, PDB code: 7pxg:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Calcium binding site 1 out
of 8 in 7pxg
Go back to
Calcium Binding Sites List in 7pxg
Calcium binding site 1 out
of 8 in the Verruculogen-Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Verruculogen-Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca2002
b:43.2
occ:1.00
|
O
|
A:ASP980
|
2.4
|
48.0
|
1.0
|
OD2
|
A:ASP985
|
2.4
|
57.5
|
1.0
|
OD1
|
A:ASP983
|
2.5
|
55.3
|
1.0
|
OD1
|
A:ASP985
|
2.5
|
57.5
|
1.0
|
O
|
A:GLN977
|
2.5
|
42.4
|
1.0
|
OD1
|
C:ASN463
|
2.5
|
36.8
|
1.0
|
CG
|
A:ASP985
|
2.8
|
57.5
|
1.0
|
ND2
|
C:ASN463
|
3.0
|
36.8
|
1.0
|
CG
|
C:ASN463
|
3.1
|
36.8
|
1.0
|
CG
|
A:ASP983
|
3.5
|
55.3
|
1.0
|
C
|
A:ASP980
|
3.6
|
48.0
|
1.0
|
C
|
A:GLN977
|
3.7
|
42.4
|
1.0
|
O
|
A:ASP983
|
3.9
|
55.3
|
1.0
|
OD2
|
A:ASP983
|
3.9
|
55.3
|
1.0
|
CA
|
A:GLN981
|
4.2
|
49.0
|
1.0
|
CA
|
A:GLN977
|
4.3
|
42.4
|
1.0
|
N
|
A:GLN981
|
4.3
|
49.0
|
1.0
|
CB
|
A:ASP985
|
4.3
|
57.5
|
1.0
|
C
|
A:GLN981
|
4.5
|
49.0
|
1.0
|
O
|
A:GLN981
|
4.5
|
49.0
|
1.0
|
C
|
A:ASP983
|
4.5
|
55.3
|
1.0
|
CA
|
A:ASP980
|
4.6
|
48.0
|
1.0
|
CB
|
C:ASN463
|
4.6
|
36.8
|
1.0
|
CB
|
A:ASP983
|
4.7
|
55.3
|
1.0
|
CB
|
A:GLN977
|
4.7
|
42.4
|
1.0
|
N
|
A:ASP980
|
4.7
|
48.0
|
1.0
|
N
|
A:PHE978
|
4.8
|
45.4
|
1.0
|
N
|
A:ASP983
|
4.8
|
55.3
|
1.0
|
CA
|
A:ASP983
|
4.9
|
55.3
|
1.0
|
O
|
C:ASN463
|
4.9
|
36.8
|
1.0
|
N
|
A:ASP985
|
5.0
|
57.5
|
1.0
|
CB
|
A:ASP980
|
5.0
|
48.0
|
1.0
|
CA
|
A:PHE978
|
5.0
|
45.4
|
1.0
|
|
Calcium binding site 2 out
of 8 in 7pxg
Go back to
Calcium Binding Sites List in 7pxg
Calcium binding site 2 out
of 8 in the Verruculogen-Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of Verruculogen-Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca2003
b:49.5
occ:1.00
|
O
|
A:ARG528
|
2.4
|
49.0
|
1.0
|
O
|
A:GLN616
|
2.4
|
49.6
|
1.0
|
O
|
A:GLY548
|
2.5
|
45.5
|
1.0
|
OD2
|
A:ASP381
|
2.5
|
53.7
|
1.0
|
OE1
|
A:GLU550
|
2.5
|
47.5
|
1.0
|
OE2
|
A:GLU550
|
2.8
|
47.5
|
1.0
|
CD
|
A:GLU550
|
3.0
|
47.5
|
1.0
|
CG
|
A:ASP381
|
3.4
|
53.7
|
1.0
|
C
|
A:GLY548
|
3.5
|
45.5
|
1.0
|
C
|
A:GLN616
|
3.6
|
49.6
|
1.0
|
C
|
A:ARG528
|
3.6
|
49.0
|
1.0
|
CA
|
A:GLY548
|
3.9
|
45.5
|
1.0
|
OD1
|
A:ASP381
|
3.9
|
53.7
|
1.0
|
CA
|
A:GLN616
|
4.2
|
49.6
|
1.0
|
CB
|
A:ASP381
|
4.3
|
53.7
|
1.0
|
CA
|
A:SER529
|
4.3
|
61.8
|
1.0
|
N
|
A:SER529
|
4.4
|
61.8
|
1.0
|
N
|
A:ARG528
|
4.4
|
49.0
|
1.0
|
NE2
|
A:GLN616
|
4.4
|
49.6
|
1.0
|
CG
|
A:GLU550
|
4.5
|
47.5
|
1.0
|
CA
|
A:ARG528
|
4.6
|
49.0
|
1.0
|
N
|
A:SER617
|
4.6
|
54.0
|
1.0
|
OH
|
A:TYR552
|
4.6
|
51.7
|
1.0
|
N
|
A:MET549
|
4.7
|
48.4
|
1.0
|
CB
|
A:GLN616
|
4.8
|
49.6
|
1.0
|
CA
|
A:SER617
|
4.9
|
54.0
|
1.0
|
CD
|
A:GLN616
|
5.0
|
49.6
|
1.0
|
N
|
A:PHE530
|
5.0
|
68.4
|
1.0
|
|
Calcium binding site 3 out
of 8 in 7pxg
Go back to
Calcium Binding Sites List in 7pxg
Calcium binding site 3 out
of 8 in the Verruculogen-Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of Verruculogen-Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca2002
b:42.1
occ:1.00
|
O
|
B:ASP980
|
2.4
|
48.4
|
1.0
|
OD2
|
B:ASP985
|
2.4
|
58.2
|
1.0
|
OD1
|
B:ASP983
|
2.5
|
55.3
|
1.0
|
OD1
|
D:ASN463
|
2.5
|
39.1
|
1.0
|
OD1
|
B:ASP985
|
2.5
|
58.2
|
1.0
|
O
|
B:GLN977
|
2.5
|
41.8
|
1.0
|
CG
|
B:ASP985
|
2.8
|
58.2
|
1.0
|
ND2
|
D:ASN463
|
3.2
|
39.1
|
1.0
|
CG
|
D:ASN463
|
3.2
|
39.1
|
1.0
|
CG
|
B:ASP983
|
3.5
|
55.3
|
1.0
|
C
|
B:ASP980
|
3.6
|
48.4
|
1.0
|
C
|
B:GLN977
|
3.7
|
41.8
|
1.0
|
O
|
B:ASP983
|
3.9
|
55.3
|
1.0
|
OD2
|
B:ASP983
|
3.9
|
55.3
|
1.0
|
CA
|
B:GLN981
|
4.2
|
49.5
|
1.0
|
CA
|
B:GLN977
|
4.3
|
41.8
|
1.0
|
N
|
B:GLN981
|
4.3
|
49.5
|
1.0
|
CB
|
B:ASP985
|
4.3
|
58.2
|
1.0
|
C
|
B:GLN981
|
4.5
|
49.5
|
1.0
|
O
|
B:GLN981
|
4.5
|
49.5
|
1.0
|
C
|
B:ASP983
|
4.5
|
55.3
|
1.0
|
CA
|
B:ASP980
|
4.6
|
48.4
|
1.0
|
CB
|
B:ASP983
|
4.7
|
55.3
|
1.0
|
O
|
D:ASN463
|
4.7
|
39.1
|
1.0
|
CB
|
D:ASN463
|
4.7
|
39.1
|
1.0
|
CB
|
B:GLN977
|
4.7
|
41.8
|
1.0
|
N
|
B:ASP980
|
4.7
|
48.4
|
1.0
|
N
|
B:PHE978
|
4.8
|
40.3
|
1.0
|
N
|
B:ASP983
|
4.8
|
55.3
|
1.0
|
CA
|
B:ASP983
|
4.9
|
55.3
|
1.0
|
N
|
B:ASP985
|
5.0
|
58.2
|
1.0
|
CB
|
B:ASP980
|
5.0
|
48.4
|
1.0
|
CA
|
B:PHE978
|
5.0
|
40.3
|
1.0
|
|
Calcium binding site 4 out
of 8 in 7pxg
Go back to
Calcium Binding Sites List in 7pxg
Calcium binding site 4 out
of 8 in the Verruculogen-Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of Verruculogen-Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca2003
b:50.5
occ:1.00
|
O
|
B:ARG528
|
2.4
|
49.8
|
1.0
|
O
|
B:GLN616
|
2.4
|
49.2
|
1.0
|
O
|
B:GLY548
|
2.5
|
46.8
|
1.0
|
OD2
|
B:ASP381
|
2.5
|
54.6
|
1.0
|
OE1
|
B:GLU550
|
2.5
|
48.2
|
1.0
|
OE2
|
B:GLU550
|
2.8
|
48.2
|
1.0
|
CD
|
B:GLU550
|
3.0
|
48.2
|
1.0
|
CG
|
B:ASP381
|
3.4
|
54.6
|
1.0
|
C
|
B:GLY548
|
3.5
|
46.8
|
1.0
|
C
|
B:GLN616
|
3.5
|
49.2
|
1.0
|
C
|
B:ARG528
|
3.6
|
49.8
|
1.0
|
CA
|
B:GLY548
|
3.9
|
46.8
|
1.0
|
OD1
|
B:ASP381
|
3.9
|
54.6
|
1.0
|
CA
|
B:GLN616
|
4.2
|
49.2
|
1.0
|
CB
|
B:ASP381
|
4.3
|
54.6
|
1.0
|
CA
|
B:SER529
|
4.3
|
61.5
|
1.0
|
N
|
B:SER529
|
4.4
|
61.5
|
1.0
|
N
|
B:ARG528
|
4.4
|
49.8
|
1.0
|
NE2
|
B:GLN616
|
4.4
|
49.2
|
1.0
|
CG
|
B:GLU550
|
4.5
|
48.2
|
1.0
|
CA
|
B:ARG528
|
4.6
|
49.8
|
1.0
|
N
|
B:SER617
|
4.6
|
54.5
|
1.0
|
OH
|
B:TYR552
|
4.6
|
50.6
|
1.0
|
N
|
B:MET549
|
4.7
|
48.6
|
1.0
|
CB
|
B:GLN616
|
4.8
|
49.2
|
1.0
|
CA
|
B:SER617
|
4.9
|
54.5
|
1.0
|
CD
|
B:GLN616
|
5.0
|
49.2
|
1.0
|
N
|
B:PHE530
|
5.0
|
69.9
|
1.0
|
|
Calcium binding site 5 out
of 8 in 7pxg
Go back to
Calcium Binding Sites List in 7pxg
Calcium binding site 5 out
of 8 in the Verruculogen-Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of Verruculogen-Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca1203
b:42.3
occ:1.00
|
O
|
C:ASP980
|
2.4
|
47.5
|
1.0
|
OD2
|
C:ASP985
|
2.4
|
57.6
|
1.0
|
OD1
|
C:ASP983
|
2.5
|
55.6
|
1.0
|
OD1
|
B:ASN463
|
2.5
|
39.3
|
1.0
|
OD1
|
C:ASP985
|
2.5
|
57.6
|
1.0
|
O
|
C:GLN977
|
2.5
|
41.8
|
1.0
|
CG
|
C:ASP985
|
2.8
|
57.6
|
1.0
|
ND2
|
B:ASN463
|
3.1
|
39.3
|
1.0
|
CG
|
B:ASN463
|
3.2
|
39.3
|
1.0
|
CG
|
C:ASP983
|
3.5
|
55.6
|
1.0
|
C
|
C:ASP980
|
3.6
|
47.5
|
1.0
|
C
|
C:GLN977
|
3.7
|
41.8
|
1.0
|
O
|
C:ASP983
|
3.9
|
55.6
|
1.0
|
OD2
|
C:ASP983
|
3.9
|
55.6
|
1.0
|
CA
|
C:GLN981
|
4.2
|
49.2
|
1.0
|
CA
|
C:GLN977
|
4.3
|
41.8
|
1.0
|
N
|
C:GLN981
|
4.3
|
49.2
|
1.0
|
CB
|
C:ASP985
|
4.3
|
57.6
|
1.0
|
C
|
C:GLN981
|
4.5
|
49.2
|
1.0
|
O
|
C:GLN981
|
4.5
|
49.2
|
1.0
|
C
|
C:ASP983
|
4.5
|
55.6
|
1.0
|
CA
|
C:ASP980
|
4.6
|
47.5
|
1.0
|
CB
|
C:ASP983
|
4.7
|
55.6
|
1.0
|
CB
|
B:ASN463
|
4.7
|
39.3
|
1.0
|
CB
|
C:GLN977
|
4.7
|
41.8
|
1.0
|
N
|
C:ASP980
|
4.7
|
47.5
|
1.0
|
N
|
C:PHE978
|
4.8
|
44.4
|
1.0
|
N
|
C:ASP983
|
4.8
|
55.6
|
1.0
|
O
|
B:ASN463
|
4.9
|
39.3
|
1.0
|
CA
|
C:ASP983
|
4.9
|
55.6
|
1.0
|
N
|
C:ASP985
|
5.0
|
57.6
|
1.0
|
CB
|
C:ASP980
|
5.0
|
47.5
|
1.0
|
CA
|
C:PHE978
|
5.0
|
44.4
|
1.0
|
|
Calcium binding site 6 out
of 8 in 7pxg
Go back to
Calcium Binding Sites List in 7pxg
Calcium binding site 6 out
of 8 in the Verruculogen-Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 6 of Verruculogen-Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca1204
b:50.5
occ:1.00
|
O
|
C:ARG528
|
2.4
|
50.8
|
1.0
|
O
|
C:GLN616
|
2.4
|
49.3
|
1.0
|
O
|
C:GLY548
|
2.5
|
47.1
|
1.0
|
OD2
|
C:ASP381
|
2.5
|
54.6
|
1.0
|
OE1
|
C:GLU550
|
2.5
|
48.2
|
1.0
|
OE2
|
C:GLU550
|
2.8
|
48.2
|
1.0
|
CD
|
C:GLU550
|
3.0
|
48.2
|
1.0
|
CG
|
C:ASP381
|
3.4
|
54.6
|
1.0
|
C
|
C:GLY548
|
3.5
|
47.1
|
1.0
|
C
|
C:GLN616
|
3.6
|
49.3
|
1.0
|
C
|
C:ARG528
|
3.6
|
50.8
|
1.0
|
CA
|
C:GLY548
|
3.9
|
47.1
|
1.0
|
OD1
|
C:ASP381
|
3.9
|
54.6
|
1.0
|
CA
|
C:GLN616
|
4.2
|
49.3
|
1.0
|
CB
|
C:ASP381
|
4.3
|
54.6
|
1.0
|
CA
|
C:SER529
|
4.3
|
63.3
|
1.0
|
N
|
C:SER529
|
4.4
|
63.3
|
1.0
|
N
|
C:ARG528
|
4.4
|
50.8
|
1.0
|
NE2
|
C:GLN616
|
4.4
|
49.3
|
1.0
|
CG
|
C:GLU550
|
4.5
|
48.2
|
1.0
|
CA
|
C:ARG528
|
4.6
|
50.8
|
1.0
|
N
|
C:SER617
|
4.6
|
54.5
|
1.0
|
OH
|
C:TYR552
|
4.6
|
51.1
|
1.0
|
N
|
C:MET549
|
4.7
|
49.1
|
1.0
|
CB
|
C:GLN616
|
4.8
|
49.3
|
1.0
|
CA
|
C:SER617
|
4.9
|
54.5
|
1.0
|
CD
|
C:GLN616
|
5.0
|
49.3
|
1.0
|
N
|
C:PHE530
|
5.0
|
70.0
|
1.0
|
|
Calcium binding site 7 out
of 8 in 7pxg
Go back to
Calcium Binding Sites List in 7pxg
Calcium binding site 7 out
of 8 in the Verruculogen-Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 7 of Verruculogen-Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca2002
b:43.6
occ:1.00
|
O
|
D:ASP980
|
2.4
|
49.1
|
1.0
|
OD2
|
D:ASP985
|
2.4
|
58.7
|
1.0
|
OD1
|
D:ASP983
|
2.5
|
56.3
|
1.0
|
OD1
|
D:ASP985
|
2.5
|
58.7
|
1.0
|
O
|
D:GLN977
|
2.5
|
43.3
|
1.0
|
OD1
|
A:ASN463
|
2.7
|
36.4
|
1.0
|
CG
|
D:ASP985
|
2.8
|
58.7
|
1.0
|
ND2
|
A:ASN463
|
3.4
|
36.4
|
1.0
|
CG
|
A:ASN463
|
3.4
|
36.4
|
1.0
|
CG
|
D:ASP983
|
3.5
|
56.3
|
1.0
|
C
|
D:ASP980
|
3.6
|
49.1
|
1.0
|
C
|
D:GLN977
|
3.7
|
43.3
|
1.0
|
O
|
D:ASP983
|
3.9
|
56.3
|
1.0
|
OD2
|
D:ASP983
|
3.9
|
56.3
|
1.0
|
CA
|
D:GLN981
|
4.2
|
50.2
|
1.0
|
CA
|
D:GLN977
|
4.3
|
43.3
|
1.0
|
N
|
D:GLN981
|
4.3
|
50.2
|
1.0
|
CB
|
D:ASP985
|
4.3
|
58.7
|
1.0
|
C
|
D:GLN981
|
4.5
|
50.2
|
1.0
|
O
|
D:GLN981
|
4.5
|
50.2
|
1.0
|
C
|
D:ASP983
|
4.5
|
56.3
|
1.0
|
CA
|
D:ASP980
|
4.6
|
49.1
|
1.0
|
CB
|
D:ASP983
|
4.7
|
56.3
|
1.0
|
CB
|
D:GLN977
|
4.7
|
43.3
|
1.0
|
N
|
D:ASP980
|
4.7
|
49.1
|
1.0
|
N
|
D:PHE978
|
4.8
|
47.8
|
1.0
|
N
|
D:ASP983
|
4.8
|
56.3
|
1.0
|
CA
|
D:ASP983
|
4.9
|
56.3
|
1.0
|
CB
|
A:ASN463
|
4.9
|
36.4
|
1.0
|
O
|
A:ASN463
|
4.9
|
36.4
|
1.0
|
N
|
D:ASP985
|
5.0
|
58.7
|
1.0
|
CB
|
D:ASP980
|
5.0
|
49.1
|
1.0
|
CA
|
D:PHE978
|
5.0
|
47.8
|
1.0
|
|
Calcium binding site 8 out
of 8 in 7pxg
Go back to
Calcium Binding Sites List in 7pxg
Calcium binding site 8 out
of 8 in the Verruculogen-Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 8 of Verruculogen-Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca2003
b:48.8
occ:1.00
|
O
|
D:ARG528
|
2.4
|
50.1
|
1.0
|
O
|
D:GLN616
|
2.4
|
50.7
|
1.0
|
O
|
D:GLY548
|
2.5
|
47.9
|
1.0
|
OD2
|
D:ASP381
|
2.5
|
54.1
|
1.0
|
OE1
|
D:GLU550
|
2.5
|
48.6
|
1.0
|
OE2
|
D:GLU550
|
2.8
|
48.6
|
1.0
|
CD
|
D:GLU550
|
3.0
|
48.6
|
1.0
|
CG
|
D:ASP381
|
3.4
|
54.1
|
1.0
|
C
|
D:GLY548
|
3.5
|
47.9
|
1.0
|
C
|
D:GLN616
|
3.5
|
50.7
|
1.0
|
C
|
D:ARG528
|
3.6
|
50.1
|
1.0
|
CA
|
D:GLY548
|
3.9
|
47.9
|
1.0
|
OD1
|
D:ASP381
|
3.9
|
54.1
|
1.0
|
CA
|
D:GLN616
|
4.2
|
50.7
|
1.0
|
CB
|
D:ASP381
|
4.3
|
54.1
|
1.0
|
CA
|
D:SER529
|
4.3
|
61.6
|
1.0
|
N
|
D:SER529
|
4.4
|
61.6
|
1.0
|
N
|
D:ARG528
|
4.4
|
50.1
|
1.0
|
NE2
|
D:GLN616
|
4.4
|
50.7
|
1.0
|
CG
|
D:GLU550
|
4.5
|
48.6
|
1.0
|
CA
|
D:ARG528
|
4.6
|
50.1
|
1.0
|
N
|
D:SER617
|
4.6
|
55.5
|
1.0
|
OH
|
D:TYR552
|
4.6
|
52.4
|
1.0
|
N
|
D:MET549
|
4.7
|
50.3
|
1.0
|
CB
|
D:GLN616
|
4.8
|
50.7
|
1.0
|
CA
|
D:SER617
|
4.9
|
55.5
|
1.0
|
CD
|
D:GLN616
|
5.0
|
50.7
|
1.0
|
N
|
D:PHE530
|
5.0
|
70.0
|
1.0
|
|
Reference:
T.Raisch,
A.Brockmann,
U.Ebbinghaus-Kintscher,
J.Freigang,
O.Gutbrod,
J.Kubicek,
B.Maertens,
O.Hofnagel,
S.Raunser.
Small Molecule Modulation of the Drosophila Slo Channel Elucidated By Cryo-Em To Be Published.
DOI: 10.1038/S41467-021-27435-W
Page generated: Fri Jul 19 03:19:59 2024
|