Calcium in PDB 7q3g: Pentameric Ligand-Gated Ion Channel, Declic at pH 7 with 10 Mm CA2+
Calcium Binding Sites:
The binding sites of Calcium atom in the Pentameric Ligand-Gated Ion Channel, Declic at pH 7 with 10 Mm CA2+
(pdb code 7q3g). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 5 binding sites of Calcium where determined in the
Pentameric Ligand-Gated Ion Channel, Declic at pH 7 with 10 Mm CA2+, PDB code: 7q3g:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
Calcium binding site 1 out
of 5 in 7q3g
Go back to
Calcium Binding Sites List in 7q3g
Calcium binding site 1 out
of 5 in the Pentameric Ligand-Gated Ion Channel, Declic at pH 7 with 10 Mm CA2+
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Pentameric Ligand-Gated Ion Channel, Declic at pH 7 with 10 Mm CA2+ within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Ca701
b:34.6
occ:1.00
|
OE2
|
A:GLU347
|
3.1
|
13.8
|
1.0
|
O
|
E:LEU477
|
3.1
|
18.7
|
1.0
|
O
|
A:PRO434
|
3.2
|
12.1
|
1.0
|
OE2
|
E:GLU480
|
3.2
|
23.8
|
1.0
|
OE1
|
A:GLU347
|
3.3
|
13.8
|
1.0
|
CD
|
A:GLU347
|
3.5
|
13.8
|
1.0
|
CB
|
E:GLN476
|
3.5
|
26.6
|
1.0
|
CG
|
E:GLU480
|
3.6
|
23.8
|
1.0
|
CD
|
E:GLU480
|
3.8
|
23.8
|
1.0
|
O
|
A:PHE436
|
4.1
|
14.6
|
1.0
|
C
|
E:LEU477
|
4.1
|
18.7
|
1.0
|
C
|
A:PRO434
|
4.2
|
12.1
|
1.0
|
C
|
E:GLN476
|
4.3
|
26.6
|
1.0
|
N
|
E:LEU477
|
4.3
|
18.7
|
1.0
|
CA
|
A:PRO434
|
4.4
|
12.1
|
1.0
|
CG
|
E:GLN476
|
4.5
|
26.6
|
1.0
|
CA
|
E:GLN476
|
4.6
|
26.6
|
1.0
|
O
|
E:GLN476
|
4.6
|
26.6
|
1.0
|
NE2
|
E:GLN338
|
4.8
|
12.2
|
1.0
|
CA
|
E:LEU477
|
4.9
|
18.7
|
1.0
|
CG
|
A:GLU347
|
4.9
|
13.8
|
1.0
|
N
|
E:GLY478
|
4.9
|
23.7
|
1.0
|
CA
|
E:GLY478
|
4.9
|
23.7
|
1.0
|
OE1
|
E:GLU480
|
5.0
|
23.8
|
1.0
|
CB
|
A:PRO434
|
5.0
|
12.1
|
1.0
|
|
Calcium binding site 2 out
of 5 in 7q3g
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Calcium Binding Sites List in 7q3g
Calcium binding site 2 out
of 5 in the Pentameric Ligand-Gated Ion Channel, Declic at pH 7 with 10 Mm CA2+
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of Pentameric Ligand-Gated Ion Channel, Declic at pH 7 with 10 Mm CA2+ within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca701
b:22.1
occ:1.00
|
OE2
|
E:GLU347
|
3.1
|
12.1
|
1.0
|
O
|
D:LEU477
|
3.1
|
12.8
|
1.0
|
O
|
E:PRO434
|
3.2
|
12.0
|
1.0
|
OE2
|
D:GLU480
|
3.2
|
22.3
|
1.0
|
OE1
|
E:GLU347
|
3.2
|
12.1
|
1.0
|
CD
|
E:GLU347
|
3.5
|
12.1
|
1.0
|
CB
|
D:GLN476
|
3.5
|
20.1
|
1.0
|
CG
|
D:GLU480
|
3.6
|
22.3
|
1.0
|
CD
|
D:GLU480
|
3.8
|
22.3
|
1.0
|
C
|
D:LEU477
|
4.1
|
12.8
|
1.0
|
O
|
E:PHE436
|
4.1
|
13.8
|
1.0
|
C
|
E:PRO434
|
4.2
|
12.0
|
1.0
|
C
|
D:GLN476
|
4.3
|
20.1
|
1.0
|
NE2
|
D:GLN338
|
4.4
|
15.8
|
1.0
|
N
|
D:LEU477
|
4.4
|
12.8
|
1.0
|
CA
|
E:PRO434
|
4.4
|
12.0
|
1.0
|
CG
|
D:GLN476
|
4.5
|
20.1
|
1.0
|
CA
|
D:GLN476
|
4.6
|
20.1
|
1.0
|
O
|
D:GLN476
|
4.6
|
20.1
|
1.0
|
CB
|
E:PRO434
|
4.9
|
12.0
|
1.0
|
N
|
D:GLY478
|
4.9
|
17.8
|
1.0
|
CA
|
D:LEU477
|
4.9
|
12.8
|
1.0
|
CG
|
E:GLU347
|
4.9
|
12.1
|
1.0
|
CA
|
D:GLY478
|
4.9
|
17.8
|
1.0
|
OE1
|
D:GLU480
|
5.0
|
22.3
|
1.0
|
|
Calcium binding site 3 out
of 5 in 7q3g
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Calcium Binding Sites List in 7q3g
Calcium binding site 3 out
of 5 in the Pentameric Ligand-Gated Ion Channel, Declic at pH 7 with 10 Mm CA2+
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of Pentameric Ligand-Gated Ion Channel, Declic at pH 7 with 10 Mm CA2+ within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca701
b:33.6
occ:1.00
|
OE2
|
D:GLU347
|
3.1
|
12.5
|
1.0
|
O
|
C:LEU477
|
3.1
|
14.1
|
1.0
|
O
|
D:PRO434
|
3.2
|
11.8
|
1.0
|
OE2
|
C:GLU480
|
3.2
|
21.8
|
1.0
|
OE1
|
D:GLU347
|
3.2
|
12.5
|
1.0
|
CD
|
D:GLU347
|
3.5
|
12.5
|
1.0
|
CB
|
C:GLN476
|
3.5
|
23.8
|
1.0
|
CG
|
C:GLU480
|
3.7
|
21.8
|
1.0
|
CD
|
C:GLU480
|
3.8
|
21.8
|
1.0
|
C
|
C:LEU477
|
4.1
|
14.1
|
1.0
|
O
|
D:PHE436
|
4.1
|
13.9
|
1.0
|
C
|
D:PRO434
|
4.2
|
11.8
|
1.0
|
C
|
C:GLN476
|
4.3
|
23.8
|
1.0
|
N
|
C:LEU477
|
4.3
|
14.1
|
1.0
|
CA
|
D:PRO434
|
4.4
|
11.8
|
1.0
|
CG
|
C:GLN476
|
4.5
|
23.8
|
1.0
|
CA
|
C:GLN476
|
4.6
|
23.8
|
1.0
|
O
|
C:GLN476
|
4.6
|
23.8
|
1.0
|
NE2
|
C:GLN338
|
4.7
|
13.2
|
1.0
|
CA
|
C:LEU477
|
4.9
|
14.1
|
1.0
|
CG
|
D:GLU347
|
4.9
|
12.5
|
1.0
|
N
|
C:GLY478
|
4.9
|
18.4
|
1.0
|
CB
|
D:PRO434
|
4.9
|
11.8
|
1.0
|
OE1
|
C:GLU480
|
5.0
|
21.8
|
1.0
|
|
Calcium binding site 4 out
of 5 in 7q3g
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Calcium Binding Sites List in 7q3g
Calcium binding site 4 out
of 5 in the Pentameric Ligand-Gated Ion Channel, Declic at pH 7 with 10 Mm CA2+
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of Pentameric Ligand-Gated Ion Channel, Declic at pH 7 with 10 Mm CA2+ within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca701
b:33.6
occ:1.00
|
OE2
|
C:GLU347
|
3.1
|
12.4
|
1.0
|
O
|
B:LEU477
|
3.1
|
14.6
|
1.0
|
OE2
|
B:GLU480
|
3.2
|
19.2
|
1.0
|
O
|
C:PRO434
|
3.2
|
11.8
|
1.0
|
OE1
|
C:GLU347
|
3.2
|
12.4
|
1.0
|
CD
|
C:GLU347
|
3.5
|
12.4
|
1.0
|
CB
|
B:GLN476
|
3.5
|
21.6
|
1.0
|
CG
|
B:GLU480
|
3.7
|
19.2
|
1.0
|
CD
|
B:GLU480
|
3.8
|
19.2
|
1.0
|
C
|
B:LEU477
|
4.1
|
14.6
|
1.0
|
O
|
C:PHE436
|
4.1
|
13.4
|
1.0
|
C
|
C:PRO434
|
4.2
|
11.8
|
1.0
|
C
|
B:GLN476
|
4.3
|
21.6
|
1.0
|
N
|
B:LEU477
|
4.3
|
14.6
|
1.0
|
NE2
|
B:GLN338
|
4.4
|
14.7
|
1.0
|
CA
|
C:PRO434
|
4.4
|
11.8
|
1.0
|
CG
|
B:GLN476
|
4.5
|
21.6
|
1.0
|
CA
|
B:GLN476
|
4.6
|
21.6
|
1.0
|
O
|
B:GLN476
|
4.6
|
21.6
|
1.0
|
CA
|
B:LEU477
|
4.9
|
14.6
|
1.0
|
CG
|
C:GLU347
|
4.9
|
12.4
|
1.0
|
N
|
B:GLY478
|
4.9
|
17.6
|
1.0
|
CB
|
C:PRO434
|
4.9
|
11.8
|
1.0
|
CD
|
B:GLN338
|
5.0
|
14.7
|
1.0
|
OE1
|
B:GLU480
|
5.0
|
19.2
|
1.0
|
CA
|
B:GLY478
|
5.0
|
17.6
|
1.0
|
|
Calcium binding site 5 out
of 5 in 7q3g
Go back to
Calcium Binding Sites List in 7q3g
Calcium binding site 5 out
of 5 in the Pentameric Ligand-Gated Ion Channel, Declic at pH 7 with 10 Mm CA2+
Mono view
Stereo pair view
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of Pentameric Ligand-Gated Ion Channel, Declic at pH 7 with 10 Mm CA2+ within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca701
b:29.0
occ:1.00
|
OE2
|
B:GLU347
|
3.1
|
11.9
|
1.0
|
O
|
A:LEU477
|
3.1
|
13.8
|
1.0
|
O
|
B:PRO434
|
3.2
|
11.2
|
1.0
|
OE2
|
A:GLU480
|
3.2
|
22.5
|
1.0
|
OE1
|
B:GLU347
|
3.2
|
11.9
|
1.0
|
CD
|
B:GLU347
|
3.5
|
11.9
|
1.0
|
CB
|
A:GLN476
|
3.5
|
23.4
|
1.0
|
CG
|
A:GLU480
|
3.7
|
22.5
|
1.0
|
CD
|
A:GLU480
|
3.8
|
22.5
|
1.0
|
C
|
A:LEU477
|
4.1
|
13.8
|
1.0
|
O
|
B:PHE436
|
4.1
|
13.2
|
1.0
|
C
|
B:PRO434
|
4.2
|
11.2
|
1.0
|
C
|
A:GLN476
|
4.3
|
23.4
|
1.0
|
N
|
A:LEU477
|
4.4
|
13.8
|
1.0
|
CA
|
B:PRO434
|
4.4
|
11.2
|
1.0
|
CG
|
A:GLN476
|
4.5
|
23.4
|
1.0
|
CA
|
A:GLN476
|
4.6
|
23.4
|
1.0
|
O
|
A:GLN476
|
4.6
|
23.4
|
1.0
|
NE2
|
A:GLN338
|
4.7
|
15.6
|
1.0
|
CA
|
A:LEU477
|
4.9
|
13.8
|
1.0
|
CG
|
B:GLU347
|
4.9
|
11.9
|
1.0
|
N
|
A:GLY478
|
4.9
|
19.4
|
1.0
|
CB
|
B:PRO434
|
5.0
|
11.2
|
1.0
|
OE1
|
A:GLU480
|
5.0
|
22.5
|
1.0
|
|
Reference:
M.Lycksell,
U.Rovsnik,
A.Hanke,
A.Martel,
R.J.Howard,
E.Lindahl.
Biophysical Characterization of Calcium-Binding and Modulatory-Domain Dynamics in A Pentameric Ligand-Gated Ion Channel. Proc.Natl.Acad.Sci.Usa V. 119 69119 2022.
ISSN: ESSN 1091-6490
PubMed: 36480474
DOI: 10.1073/PNAS.2210669119
Page generated: Fri Jul 19 03:23:31 2024
|