Calcium in PDB 7uai: Meprin Alpha Helix in Complex with Fetuin-B
Enzymatic activity of Meprin Alpha Helix in Complex with Fetuin-B
All present enzymatic activity of Meprin Alpha Helix in Complex with Fetuin-B:
3.4.24.18;
Other elements in 7uai:
The structure of Meprin Alpha Helix in Complex with Fetuin-B also contains other interesting chemical elements:
Calcium Binding Sites:
The binding sites of Calcium atom in the Meprin Alpha Helix in Complex with Fetuin-B
(pdb code 7uai). This binding sites where shown within
5.0 Angstroms radius around Calcium atom.
In total 8 binding sites of Calcium where determined in the
Meprin Alpha Helix in Complex with Fetuin-B, PDB code: 7uai:
Jump to Calcium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Calcium binding site 1 out
of 8 in 7uai
Go back to
Calcium Binding Sites List in 7uai
Calcium binding site 1 out
of 8 in the Meprin Alpha Helix in Complex with Fetuin-B
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 1 of Meprin Alpha Helix in Complex with Fetuin-B within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca701
b:118.5
occ:1.00
|
OD1
|
E:ASP288
|
2.3
|
108.5
|
1.0
|
|
OD1
|
E:ASP285
|
2.3
|
114.1
|
1.0
|
|
OD2
|
E:ASP285
|
2.3
|
114.1
|
1.0
|
|
O
|
E:THR287
|
2.3
|
112.0
|
1.0
|
|
O
|
E:GLY282
|
2.4
|
112.2
|
1.0
|
|
CG
|
E:ASP285
|
2.7
|
114.1
|
1.0
|
|
C
|
E:THR287
|
3.3
|
112.0
|
1.0
|
|
C
|
E:GLY282
|
3.4
|
112.2
|
1.0
|
|
CG
|
E:ASP288
|
3.5
|
108.5
|
1.0
|
|
CA
|
E:ASP288
|
4.0
|
108.5
|
1.0
|
|
N
|
E:ASP288
|
4.0
|
108.5
|
1.0
|
|
N
|
E:GLY282
|
4.1
|
112.2
|
1.0
|
|
CA
|
E:GLY282
|
4.1
|
112.2
|
1.0
|
|
CB
|
E:ASP285
|
4.2
|
114.1
|
1.0
|
|
CB
|
E:GLN281
|
4.2
|
104.2
|
1.0
|
|
CB
|
E:ASP288
|
4.3
|
108.5
|
1.0
|
|
CA
|
E:THR287
|
4.3
|
112.0
|
1.0
|
|
N
|
E:THR283
|
4.3
|
120.2
|
1.0
|
|
OD2
|
E:ASP288
|
4.4
|
108.5
|
1.0
|
|
N
|
E:THR287
|
4.5
|
112.0
|
1.0
|
|
CA
|
E:THR283
|
4.5
|
120.2
|
1.0
|
|
C
|
E:GLN281
|
4.5
|
104.2
|
1.0
|
|
OE1
|
E:GLN281
|
4.5
|
104.2
|
1.0
|
|
O
|
E:LEU329
|
4.6
|
96.5
|
1.0
|
|
N
|
E:LEU329
|
4.8
|
96.5
|
1.0
|
|
CB
|
E:ALA328
|
4.9
|
99.0
|
1.0
|
|
CA
|
E:ALA328
|
4.9
|
99.0
|
1.0
|
|
CA
|
E:GLN281
|
4.9
|
104.2
|
1.0
|
|
C
|
E:ASP285
|
5.0
|
114.1
|
1.0
|
|
Calcium binding site 2 out
of 8 in 7uai
Go back to
Calcium Binding Sites List in 7uai
Calcium binding site 2 out
of 8 in the Meprin Alpha Helix in Complex with Fetuin-B
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 2 of Meprin Alpha Helix in Complex with Fetuin-B within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Ca703
b:125.0
occ:1.00
|
O
|
E:TYR313
|
2.3
|
118.1
|
1.0
|
|
OG1
|
E:THR303
|
2.4
|
119.4
|
1.0
|
|
O
|
E:THR270
|
2.4
|
112.2
|
1.0
|
|
OD1
|
E:ASP422
|
2.4
|
110.0
|
1.0
|
|
OD2
|
E:ASP422
|
2.6
|
110.0
|
1.0
|
|
OD2
|
E:ASP301
|
2.8
|
120.0
|
1.0
|
|
CG
|
E:ASP422
|
2.8
|
110.0
|
1.0
|
|
CB
|
E:THR303
|
3.0
|
119.4
|
1.0
|
|
OG1
|
E:THR270
|
3.4
|
112.2
|
1.0
|
|
C
|
E:TYR313
|
3.5
|
118.1
|
1.0
|
|
C
|
E:THR270
|
3.5
|
112.2
|
1.0
|
|
N
|
E:TYR313
|
3.7
|
118.1
|
1.0
|
|
CG
|
E:ASP301
|
3.7
|
120.0
|
1.0
|
|
CB
|
E:ASP301
|
3.9
|
120.0
|
1.0
|
|
CB
|
E:THR270
|
4.0
|
112.2
|
1.0
|
|
N
|
E:THR303
|
4.0
|
119.4
|
1.0
|
|
CG2
|
E:THR303
|
4.0
|
119.4
|
1.0
|
|
CA
|
E:THR270
|
4.1
|
112.2
|
1.0
|
|
CA
|
E:THR303
|
4.1
|
119.4
|
1.0
|
|
CA
|
E:TYR313
|
4.2
|
118.1
|
1.0
|
|
CB
|
E:ASP422
|
4.3
|
110.0
|
1.0
|
|
N
|
E:PHE314
|
4.6
|
111.8
|
1.0
|
|
N
|
E:PHE271
|
4.7
|
113.8
|
1.0
|
|
CA
|
E:PHE314
|
4.8
|
111.8
|
1.0
|
|
C
|
E:GLY312
|
4.8
|
123.7
|
1.0
|
|
CB
|
E:PHE314
|
4.8
|
111.8
|
1.0
|
|
CB
|
E:PHE271
|
4.9
|
113.8
|
1.0
|
|
OD1
|
E:ASP301
|
4.9
|
120.0
|
1.0
|
|
CB
|
E:TYR313
|
4.9
|
118.1
|
1.0
|
|
N
|
E:GLU272
|
4.9
|
115.5
|
1.0
|
|
N
|
E:HIS302
|
5.0
|
116.2
|
1.0
|
|
Calcium binding site 3 out
of 8 in 7uai
Go back to
Calcium Binding Sites List in 7uai
Calcium binding site 3 out
of 8 in the Meprin Alpha Helix in Complex with Fetuin-B
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 3 of Meprin Alpha Helix in Complex with Fetuin-B within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca701
b:101.0
occ:1.00
|
OD1
|
B:ASP285
|
2.2
|
98.6
|
1.0
|
|
OD1
|
B:ASP288
|
2.3
|
90.1
|
1.0
|
|
O
|
B:THR287
|
2.3
|
97.0
|
1.0
|
|
O
|
B:GLY282
|
2.3
|
94.8
|
1.0
|
|
CG
|
B:ASP285
|
2.7
|
98.6
|
1.0
|
|
OD2
|
B:ASP285
|
2.8
|
98.6
|
1.0
|
|
C
|
B:THR287
|
3.3
|
97.0
|
1.0
|
|
C
|
B:GLY282
|
3.4
|
94.8
|
1.0
|
|
CG
|
B:ASP288
|
3.4
|
90.1
|
1.0
|
|
N
|
B:GLY282
|
3.9
|
94.8
|
1.0
|
|
N
|
B:ASP288
|
4.0
|
90.1
|
1.0
|
|
CA
|
B:ASP288
|
4.0
|
90.1
|
1.0
|
|
CB
|
B:GLN281
|
4.1
|
84.1
|
1.0
|
|
CA
|
B:GLY282
|
4.1
|
94.8
|
1.0
|
|
CB
|
B:ASP285
|
4.2
|
98.6
|
1.0
|
|
C
|
B:GLN281
|
4.2
|
84.1
|
1.0
|
|
OD2
|
B:ASP288
|
4.3
|
90.1
|
1.0
|
|
CB
|
B:ASP288
|
4.3
|
90.1
|
1.0
|
|
CA
|
B:THR287
|
4.4
|
97.0
|
1.0
|
|
N
|
B:THR283
|
4.4
|
107.0
|
1.0
|
|
N
|
B:THR287
|
4.4
|
97.0
|
1.0
|
|
O
|
B:LEU329
|
4.5
|
75.0
|
1.0
|
|
CA
|
B:THR283
|
4.5
|
107.0
|
1.0
|
|
N
|
B:LEU329
|
4.7
|
75.0
|
1.0
|
|
CA
|
B:GLN281
|
4.7
|
84.1
|
1.0
|
|
O
|
B:GLN281
|
4.7
|
84.1
|
1.0
|
|
OE1
|
B:GLN281
|
4.8
|
84.1
|
1.0
|
|
CA
|
B:ALA328
|
4.8
|
79.7
|
1.0
|
|
O
|
B:ASP285
|
4.9
|
98.6
|
1.0
|
|
CB
|
B:ALA328
|
4.9
|
79.7
|
1.0
|
|
C
|
B:ASP285
|
5.0
|
98.6
|
1.0
|
|
C
|
B:ASP286
|
5.0
|
103.4
|
1.0
|
|
Calcium binding site 4 out
of 8 in 7uai
Go back to
Calcium Binding Sites List in 7uai
Calcium binding site 4 out
of 8 in the Meprin Alpha Helix in Complex with Fetuin-B
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 4 of Meprin Alpha Helix in Complex with Fetuin-B within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Ca703
b:74.6
occ:1.00
|
OG1
|
B:THR303
|
2.3
|
70.8
|
1.0
|
|
O
|
B:TYR313
|
2.4
|
77.7
|
1.0
|
|
OD2
|
B:ASP422
|
2.4
|
68.5
|
1.0
|
|
OD1
|
B:ASP422
|
2.4
|
68.5
|
1.0
|
|
O
|
B:THR270
|
2.4
|
72.5
|
1.0
|
|
CG
|
B:ASP422
|
2.7
|
68.5
|
1.0
|
|
OD2
|
B:ASP301
|
2.9
|
78.6
|
1.0
|
|
OE2
|
B:GLU272
|
3.2
|
77.1
|
1.0
|
|
CB
|
B:THR303
|
3.2
|
70.8
|
1.0
|
|
OE1
|
B:GLU272
|
3.2
|
77.1
|
1.0
|
|
C
|
B:TYR313
|
3.5
|
77.7
|
1.0
|
|
CD
|
B:GLU272
|
3.6
|
77.1
|
1.0
|
|
C
|
B:THR270
|
3.6
|
72.5
|
1.0
|
|
N
|
B:TYR313
|
3.7
|
77.7
|
1.0
|
|
CG
|
B:ASP301
|
3.8
|
78.6
|
1.0
|
|
N
|
B:THR303
|
3.8
|
70.8
|
1.0
|
|
CB
|
B:ASP301
|
3.9
|
78.6
|
1.0
|
|
CB
|
B:THR270
|
4.1
|
72.5
|
1.0
|
|
CA
|
B:THR303
|
4.1
|
70.8
|
1.0
|
|
CA
|
B:TYR313
|
4.1
|
77.7
|
1.0
|
|
CA
|
B:THR270
|
4.1
|
72.5
|
1.0
|
|
OG1
|
B:THR270
|
4.2
|
72.5
|
1.0
|
|
CB
|
B:ASP422
|
4.3
|
68.5
|
1.0
|
|
CG2
|
B:THR303
|
4.3
|
70.8
|
1.0
|
|
N
|
B:PHE314
|
4.6
|
73.0
|
1.0
|
|
CB
|
B:TYR313
|
4.7
|
77.7
|
1.0
|
|
N
|
B:PHE271
|
4.7
|
70.9
|
1.0
|
|
N
|
B:HIS302
|
4.7
|
70.0
|
1.0
|
|
OD1
|
B:ASP423
|
4.8
|
71.4
|
1.0
|
|
C
|
B:GLY312
|
4.8
|
81.4
|
1.0
|
|
N
|
B:GLU272
|
4.8
|
77.1
|
1.0
|
|
CB
|
B:PHE271
|
4.9
|
70.9
|
1.0
|
|
OD1
|
B:ASP301
|
5.0
|
78.6
|
1.0
|
|
CA
|
B:PHE314
|
5.0
|
73.0
|
1.0
|
|
C
|
B:PHE271
|
5.0
|
70.9
|
1.0
|
|
Calcium binding site 5 out
of 8 in 7uai
Go back to
Calcium Binding Sites List in 7uai
Calcium binding site 5 out
of 8 in the Meprin Alpha Helix in Complex with Fetuin-B
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 5 of Meprin Alpha Helix in Complex with Fetuin-B within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca701
b:101.7
occ:1.00
|
OD1
|
C:ASP288
|
2.3
|
91.0
|
1.0
|
|
OD1
|
C:ASP285
|
2.3
|
95.2
|
1.0
|
|
OD2
|
C:ASP285
|
2.3
|
95.2
|
1.0
|
|
O
|
C:THR287
|
2.3
|
97.5
|
1.0
|
|
O
|
C:GLY282
|
2.4
|
92.4
|
1.0
|
|
CG
|
C:ASP285
|
2.7
|
95.2
|
1.0
|
|
C
|
C:THR287
|
3.3
|
97.5
|
1.0
|
|
C
|
C:GLY282
|
3.4
|
92.4
|
1.0
|
|
CG
|
C:ASP288
|
3.5
|
91.0
|
1.0
|
|
N
|
C:GLY282
|
3.8
|
92.4
|
1.0
|
|
CA
|
C:GLY282
|
3.9
|
92.4
|
1.0
|
|
N
|
C:ASP288
|
3.9
|
91.0
|
1.0
|
|
CA
|
C:ASP288
|
3.9
|
91.0
|
1.0
|
|
CB
|
C:ASP285
|
4.1
|
95.2
|
1.0
|
|
CB
|
C:ASP288
|
4.3
|
91.0
|
1.0
|
|
N
|
C:THR287
|
4.3
|
97.5
|
1.0
|
|
CA
|
C:THR287
|
4.4
|
97.5
|
1.0
|
|
OD2
|
C:ASP288
|
4.4
|
91.0
|
1.0
|
|
N
|
C:THR283
|
4.4
|
98.6
|
1.0
|
|
C
|
C:GLN281
|
4.4
|
81.6
|
1.0
|
|
CB
|
C:GLN281
|
4.4
|
81.6
|
1.0
|
|
O
|
C:LEU329
|
4.5
|
74.9
|
1.0
|
|
N
|
C:LEU329
|
4.6
|
74.9
|
1.0
|
|
CA
|
C:ALA328
|
4.7
|
79.9
|
1.0
|
|
OE1
|
C:GLN281
|
4.7
|
81.6
|
1.0
|
|
CB
|
C:ALA328
|
4.7
|
79.9
|
1.0
|
|
CA
|
C:THR283
|
4.8
|
98.6
|
1.0
|
|
C
|
C:ASP285
|
4.9
|
95.2
|
1.0
|
|
CA
|
C:GLN281
|
4.9
|
81.6
|
1.0
|
|
O
|
C:ASP285
|
5.0
|
95.2
|
1.0
|
|
CA
|
C:ASP285
|
5.0
|
95.2
|
1.0
|
|
O
|
C:GLN281
|
5.0
|
81.6
|
1.0
|
|
Calcium binding site 6 out
of 8 in 7uai
Go back to
Calcium Binding Sites List in 7uai
Calcium binding site 6 out
of 8 in the Meprin Alpha Helix in Complex with Fetuin-B
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 6 of Meprin Alpha Helix in Complex with Fetuin-B within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Ca703
b:83.2
occ:1.00
|
OG1
|
C:THR303
|
2.3
|
80.8
|
1.0
|
|
O
|
C:TYR313
|
2.4
|
86.2
|
1.0
|
|
OD1
|
C:ASP422
|
2.4
|
75.9
|
1.0
|
|
OD2
|
C:ASP422
|
2.5
|
75.9
|
1.0
|
|
O
|
C:THR270
|
2.5
|
78.8
|
1.0
|
|
CG
|
C:ASP422
|
2.8
|
75.9
|
1.0
|
|
OE2
|
C:GLU272
|
3.0
|
86.2
|
1.0
|
|
CB
|
C:THR303
|
3.2
|
80.8
|
1.0
|
|
OD2
|
C:ASP301
|
3.2
|
85.3
|
1.0
|
|
OG1
|
C:THR270
|
3.5
|
78.8
|
1.0
|
|
C
|
C:TYR313
|
3.6
|
86.2
|
1.0
|
|
C
|
C:THR270
|
3.6
|
78.8
|
1.0
|
|
N
|
C:THR303
|
3.8
|
80.8
|
1.0
|
|
N
|
C:TYR313
|
3.9
|
86.2
|
1.0
|
|
CB
|
C:ASP301
|
4.0
|
85.3
|
1.0
|
|
CB
|
C:THR270
|
4.0
|
78.8
|
1.0
|
|
CD
|
C:GLU272
|
4.1
|
86.2
|
1.0
|
|
CG
|
C:ASP301
|
4.1
|
85.3
|
1.0
|
|
CA
|
C:THR270
|
4.1
|
78.8
|
1.0
|
|
CA
|
C:THR303
|
4.1
|
80.8
|
1.0
|
|
CA
|
C:TYR313
|
4.2
|
86.2
|
1.0
|
|
CB
|
C:ASP422
|
4.3
|
75.9
|
1.0
|
|
CG2
|
C:THR303
|
4.3
|
80.8
|
1.0
|
|
OD1
|
C:ASP423
|
4.4
|
76.5
|
1.0
|
|
OE1
|
C:GLU272
|
4.5
|
86.2
|
1.0
|
|
N
|
C:PHE314
|
4.7
|
80.6
|
1.0
|
|
N
|
C:HIS302
|
4.7
|
78.3
|
1.0
|
|
CB
|
C:TYR313
|
4.7
|
86.2
|
1.0
|
|
N
|
C:PHE271
|
4.8
|
77.7
|
1.0
|
|
N
|
C:GLU272
|
4.9
|
86.2
|
1.0
|
|
N
|
C:ASP423
|
4.9
|
76.5
|
1.0
|
|
CA
|
C:PHE314
|
4.9
|
80.6
|
1.0
|
|
CG
|
C:ASP423
|
5.0
|
76.5
|
1.0
|
|
CB
|
C:PHE271
|
5.0
|
77.7
|
1.0
|
|
Calcium binding site 7 out
of 8 in 7uai
Go back to
Calcium Binding Sites List in 7uai
Calcium binding site 7 out
of 8 in the Meprin Alpha Helix in Complex with Fetuin-B
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 7 of Meprin Alpha Helix in Complex with Fetuin-B within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca701
b:90.0
occ:1.00
|
OD1
|
D:ASP288
|
2.3
|
86.2
|
1.0
|
|
OD1
|
D:ASP285
|
2.3
|
92.5
|
1.0
|
|
OD2
|
D:ASP285
|
2.3
|
92.5
|
1.0
|
|
O
|
D:THR287
|
2.4
|
91.2
|
1.0
|
|
O
|
D:GLY282
|
2.4
|
92.8
|
1.0
|
|
CG
|
D:ASP285
|
2.7
|
92.5
|
1.0
|
|
C
|
D:GLY282
|
3.4
|
92.8
|
1.0
|
|
C
|
D:THR287
|
3.4
|
91.2
|
1.0
|
|
CG
|
D:ASP288
|
3.5
|
86.2
|
1.0
|
|
N
|
D:GLY282
|
4.0
|
92.8
|
1.0
|
|
CA
|
D:ASP288
|
4.0
|
86.2
|
1.0
|
|
N
|
D:ASP288
|
4.0
|
86.2
|
1.0
|
|
CA
|
D:GLY282
|
4.1
|
92.8
|
1.0
|
|
CB
|
D:ASP285
|
4.2
|
92.5
|
1.0
|
|
CB
|
D:GLN281
|
4.2
|
79.7
|
1.0
|
|
C
|
D:GLN281
|
4.3
|
79.7
|
1.0
|
|
N
|
D:THR283
|
4.3
|
102.5
|
1.0
|
|
CB
|
D:ASP288
|
4.4
|
86.2
|
1.0
|
|
OD2
|
D:ASP288
|
4.4
|
86.2
|
1.0
|
|
CA
|
D:THR287
|
4.4
|
91.2
|
1.0
|
|
N
|
D:THR287
|
4.5
|
91.2
|
1.0
|
|
CA
|
D:THR283
|
4.6
|
102.5
|
1.0
|
|
OE1
|
D:GLN281
|
4.6
|
79.7
|
1.0
|
|
CA
|
D:GLN281
|
4.7
|
79.7
|
1.0
|
|
O
|
D:GLN281
|
4.8
|
79.7
|
1.0
|
|
N
|
D:LEU329
|
4.8
|
72.9
|
1.0
|
|
CB
|
D:ALA328
|
4.8
|
75.0
|
1.0
|
|
C
|
D:ASP285
|
4.9
|
92.5
|
1.0
|
|
CA
|
D:ALA328
|
4.9
|
75.0
|
1.0
|
|
C
|
D:ASP286
|
5.0
|
95.4
|
1.0
|
|
CA
|
D:ASP285
|
5.0
|
92.5
|
1.0
|
|
Calcium binding site 8 out
of 8 in 7uai
Go back to
Calcium Binding Sites List in 7uai
Calcium binding site 8 out
of 8 in the Meprin Alpha Helix in Complex with Fetuin-B
 Mono view
 Stereo pair view
|
|
A full contact list of Calcium with other atoms in the Ca binding
site number 8 of Meprin Alpha Helix in Complex with Fetuin-B within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Ca702
b:75.9
occ:1.00
|
OG1
|
D:THR303
|
2.3
|
71.8
|
1.0
|
|
O
|
D:TYR313
|
2.4
|
77.9
|
1.0
|
|
O
|
D:THR270
|
2.4
|
72.7
|
1.0
|
|
OD2
|
D:ASP422
|
2.4
|
70.8
|
1.0
|
|
OD1
|
D:ASP422
|
2.5
|
70.8
|
1.0
|
|
OD2
|
D:ASP301
|
2.6
|
77.0
|
1.0
|
|
CG
|
D:ASP422
|
2.8
|
70.8
|
1.0
|
|
OE1
|
D:GLU272
|
3.0
|
77.7
|
1.0
|
|
CB
|
D:THR303
|
3.1
|
71.8
|
1.0
|
|
OE2
|
D:GLU272
|
3.2
|
77.7
|
1.0
|
|
CD
|
D:GLU272
|
3.5
|
77.7
|
1.0
|
|
C
|
D:TYR313
|
3.5
|
77.9
|
1.0
|
|
CG
|
D:ASP301
|
3.5
|
77.0
|
1.0
|
|
C
|
D:THR270
|
3.6
|
72.7
|
1.0
|
|
N
|
D:TYR313
|
3.7
|
77.9
|
1.0
|
|
CB
|
D:ASP301
|
3.8
|
77.0
|
1.0
|
|
N
|
D:THR303
|
3.8
|
71.8
|
1.0
|
|
CA
|
D:THR303
|
4.0
|
71.8
|
1.0
|
|
CA
|
D:TYR313
|
4.1
|
77.9
|
1.0
|
|
CA
|
D:THR270
|
4.1
|
72.7
|
1.0
|
|
OG1
|
D:THR270
|
4.2
|
72.7
|
1.0
|
|
CB
|
D:THR270
|
4.2
|
72.7
|
1.0
|
|
CG2
|
D:THR303
|
4.3
|
71.8
|
1.0
|
|
CB
|
D:ASP422
|
4.3
|
70.8
|
1.0
|
|
N
|
D:PHE314
|
4.6
|
75.8
|
1.0
|
|
CB
|
D:TYR313
|
4.6
|
77.9
|
1.0
|
|
N
|
D:PHE271
|
4.7
|
71.6
|
1.0
|
|
OD1
|
D:ASP301
|
4.7
|
77.0
|
1.0
|
|
N
|
D:HIS302
|
4.7
|
70.9
|
1.0
|
|
N
|
D:GLU272
|
4.8
|
77.7
|
1.0
|
|
C
|
D:GLY312
|
4.8
|
82.0
|
1.0
|
|
CB
|
D:PHE271
|
4.8
|
71.6
|
1.0
|
|
CG
|
D:GLU272
|
4.9
|
77.7
|
1.0
|
|
CA
|
D:ASP301
|
5.0
|
77.0
|
1.0
|
|
CA
|
D:GLY312
|
5.0
|
82.0
|
1.0
|
|
Reference:
C.Bayly-Jones,
C.J.Lupton,
C.Fritz,
H.Venugopal,
D.Ramsbeck,
M.Wermann,
C.Jager,
A.De Marco,
S.Schilling,
D.Schlenzig,
J.C.Whisstock.
Helical Ultrastructure of the Metalloprotease Meprin Alpha in Complex with A Small Molecule Inhibitor. Nat Commun V. 13 6178 2022.
ISSN: ESSN 2041-1723
PubMed: 36261433
DOI: 10.1038/S41467-022-33893-7
Page generated: Fri Jul 19 04:45:39 2024
|
