Calcium in PDB 5gmf: Crystal Structure of Monkey TLR7 in Complex with Guanosine and Polyu

The structure of Crystal Structure of Monkey TLR7 in Complex with Guanosine and Polyu, PDB code: 5gmf was solved by Z.Zhang, U.Ohto, T.Shimizu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.01 / 2.50
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	98.084, 111.335, 113.376, 93.83, 94.34, 91.48
R / Rfree (%)	20.8 / 24.3

The binding sites of Calcium atom in the Crystal Structure of Monkey TLR7 in Complex with Guanosine and Polyu (pdb code 5gmf). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 4 binding sites of Calcium where determined in the Crystal Structure of Monkey TLR7 in Complex with Guanosine and Polyu, PDB code: 5gmf:
Jump to Calcium binding site number: 1; 2; 3; 4;

Calcium binding site 1 out of 4 in the Crystal Structure of Monkey TLR7 in Complex with Guanosine and Polyu


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Monkey TLR7 in Complex with Guanosine and Polyu within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca901 b:57.8 occ:1.00 OD1 A:ASP829 2.3 54.3 1.0 CG A:ASP829 3.5 53.2 1.0 OD2 A:ASP829 4.0 45.1 1.0 O A:SER827 4.3 59.3 1.0 CB A:ASP829 4.7 55.8 1.0 NE2 A:GLN799 4.9 54.4 1.0 C A:SER827 4.9 62.2 1.0 O A:LEU828 4.9 63.5 1.0

Calcium binding site 2 out of 4 in the Crystal Structure of Monkey TLR7 in Complex with Guanosine and Polyu


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Monkey TLR7 in Complex with Guanosine and Polyu within 5.0Å range: probe atom residue distance (Å) B Occ B:Ca902 b:53.1 occ:1.00 OD1 B:ASP829 2.3 57.2 1.0 CG B:ASP829 3.5 52.8 1.0 OD2 B:ASP829 4.0 55.9 1.0 O B:SER827 4.4 53.9 1.0 CB B:ASP829 4.8 49.7 1.0 NE2 B:GLN799 4.9 52.0 1.0 O B:LEU828 4.9 55.9 1.0 C B:SER827 5.0 50.3 1.0

Calcium binding site 3 out of 4 in the Crystal Structure of Monkey TLR7 in Complex with Guanosine and Polyu


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 3 of Crystal Structure of Monkey TLR7 in Complex with Guanosine and Polyu within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca902 b:54.5 occ:1.00 OD1 D:ASP829 2.3 53.9 1.0 CG D:ASP829 3.5 50.5 1.0 OD2 D:ASP829 4.1 51.2 1.0 O D:SER827 4.4 58.8 1.0 NE2 D:GLN799 4.7 45.4 1.0 CB D:ASP829 4.8 49.7 1.0 O D:LEU828 4.9 48.4 1.0 C D:SER827 4.9 57.8 1.0

Calcium binding site 4 out of 4 in the Crystal Structure of Monkey TLR7 in Complex with Guanosine and Polyu


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 4 of Crystal Structure of Monkey TLR7 in Complex with Guanosine and Polyu within 5.0Å range: probe atom residue distance (Å) B Occ D:Ca903 b:60.5 occ:1.00 O D:TRP29 2.3 69.3 1.0 C D:TRP29 3.6 66.3 1.0 CA D:PHE30 4.4 52.6 1.0 N D:PHE30 4.4 62.1 1.0 CA D:TRP29 4.6 68.1 1.0 CD D:PRO31 4.8 46.0 1.0 C D:PHE30 4.9 45.7 1.0 N D:PRO31 4.9 43.7 1.0

Z.Zhang, U.Ohto, T.Shibata, E.Krayukhina, M.Taoka, Y.Yamauchi, H.Tanji, T.Isobe, S.Uchiyama, K.Miyake, T.Shimizu. Structural Analysis Reveals That Toll-Like Receptor 7 Is A Dual Receptor For Guanosine and Single-Stranded Rna Immunity V. 45 737 2016.
ISSN: ISSN 1074-7613
PubMed: 27742543
DOI: 10.1016/J.IMMUNI.2016.09.011