Calcium in PDB 6cn2: Crystal Structure of Zebrafish Phosphatidylinositol-4-Phosphate 5- Kinase Alpha Isoform D236N with Bound Atp/CA2+

Protein crystallography data

The structure of Crystal Structure of Zebrafish Phosphatidylinositol-4-Phosphate 5- Kinase Alpha Isoform D236N with Bound Atp/CA2+, PDB code: 6cn2 was solved by X.Zeng, D.Sui, J.Hu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 36.07 / 3.10
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 89.036, 89.036, 157.783, 90.00, 90.00, 90.00
R / Rfree (%) 22.6 / 25.9

Calcium Binding Sites:

The binding sites of Calcium atom in the Crystal Structure of Zebrafish Phosphatidylinositol-4-Phosphate 5- Kinase Alpha Isoform D236N with Bound Atp/CA2+ (pdb code 6cn2). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of Zebrafish Phosphatidylinositol-4-Phosphate 5- Kinase Alpha Isoform D236N with Bound Atp/CA2+, PDB code: 6cn2:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in 6cn2

Go back to Calcium Binding Sites List in 6cn2
Calcium binding site 1 out of 2 in the Crystal Structure of Zebrafish Phosphatidylinositol-4-Phosphate 5- Kinase Alpha Isoform D236N with Bound Atp/CA2+


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Zebrafish Phosphatidylinositol-4-Phosphate 5- Kinase Alpha Isoform D236N with Bound Atp/CA2+ within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca502

b:88.5
occ:1.00
O2A A:ATP501 2.5 79.1 1.0
O2G A:ATP501 2.8 95.7 1.0
OD2 A:ASP378 2.9 74.9 1.0
OG A:SER301 3.3 63.5 1.0
O1G A:ATP501 3.4 0.2 1.0
O A:ASP299 3.5 0.2 1.0
PG A:ATP501 3.5 0.5 1.0
CB A:ASP378 3.7 67.5 1.0
NZ A:LYS238 3.7 75.5 1.0
CG A:ASP378 3.7 79.7 1.0
O A:HOH601 3.7 65.4 1.0
O3B A:ATP501 3.8 96.6 1.0
CE A:LYS238 4.0 69.8 1.0
PA A:ATP501 4.0 84.3 1.0
CB A:SER301 4.6 67.4 1.0
ND2 A:ASN236 4.6 72.1 1.0
C A:ASP299 4.7 0.5 1.0
O1A A:ATP501 4.7 84.3 1.0
N A:SER301 4.8 69.7 1.0
OD1 A:ASP378 4.9 78.6 1.0
O3A A:ATP501 4.9 83.9 1.0
PB A:ATP501 5.0 93.1 1.0
O1B A:ATP501 5.0 88.5 1.0
C5' A:ATP501 5.0 78.4 1.0

Calcium binding site 2 out of 2 in 6cn2

Go back to Calcium Binding Sites List in 6cn2
Calcium binding site 2 out of 2 in the Crystal Structure of Zebrafish Phosphatidylinositol-4-Phosphate 5- Kinase Alpha Isoform D236N with Bound Atp/CA2+


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Zebrafish Phosphatidylinositol-4-Phosphate 5- Kinase Alpha Isoform D236N with Bound Atp/CA2+ within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Ca503

b:91.1
occ:1.00
O1B A:ATP501 2.6 88.5 1.0
OD1 A:ASP378 2.7 78.6 1.0
OD2 A:ASP378 2.7 74.9 1.0
O1G A:ATP501 3.1 0.2 1.0
CG A:ASP378 3.1 79.7 1.0
OE2 A:GLU177 3.7 78.8 1.0
PB A:ATP501 4.1 93.1 1.0
PG A:ATP501 4.4 0.5 1.0
O3B A:ATP501 4.6 96.6 1.0
CB A:ASP378 4.7 67.5 1.0
NZ A:LYS171 4.7 78.7 1.0
CD A:GLU177 4.7 80.4 1.0
O3A A:ATP501 5.0 83.9 1.0

Reference:

X.Zeng, A.Uyar, D.Sui, N.Donyapour, D.Wu, A.Dickson, J.Hu. Structural Insights Into Lethal Contractural Syndrome Type 3 (LCCS3) Caused By A Missense Mutation of PIP5K Gamma. Biochem. J. V. 475 2257 2018.
ISSN: ESSN 1470-8728
PubMed: 29959184
DOI: 10.1042/BCJ20180326
Page generated: Sat Dec 12 06:01:36 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy