Calcium in PDB 6cn2: Crystal Structure of Zebrafish Phosphatidylinositol-4-Phosphate 5- Kinase Alpha Isoform D236N with Bound Atp/CA2+

The structure of Crystal Structure of Zebrafish Phosphatidylinositol-4-Phosphate 5- Kinase Alpha Isoform D236N with Bound Atp/CA2+, PDB code: 6cn2 was solved by X.Zeng, D.Sui, J.Hu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.07 / 3.10
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	89.036, 89.036, 157.783, 90.00, 90.00, 90.00
R / Rfree (%)	22.6 / 25.9

The binding sites of Calcium atom in the Crystal Structure of Zebrafish Phosphatidylinositol-4-Phosphate 5- Kinase Alpha Isoform D236N with Bound Atp/CA2+ (pdb code 6cn2). This binding sites where shown within 5.0 Angstroms radius around Calcium atom.
In total 2 binding sites of Calcium where determined in the Crystal Structure of Zebrafish Phosphatidylinositol-4-Phosphate 5- Kinase Alpha Isoform D236N with Bound Atp/CA2+, PDB code: 6cn2:
Jump to Calcium binding site number: 1; 2;

Calcium binding site 1 out of 2 in the Crystal Structure of Zebrafish Phosphatidylinositol-4-Phosphate 5- Kinase Alpha Isoform D236N with Bound Atp/CA2+


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 1 of Crystal Structure of Zebrafish Phosphatidylinositol-4-Phosphate 5- Kinase Alpha Isoform D236N with Bound Atp/CA2+ within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca502 b:88.5 occ:1.00 O2A A:ATP501 2.5 79.1 1.0 O2G A:ATP501 2.8 95.7 1.0 OD2 A:ASP378 2.9 74.9 1.0 OG A:SER301 3.3 63.5 1.0 O1G A:ATP501 3.4 0.2 1.0 O A:ASP299 3.5 0.2 1.0 PG A:ATP501 3.5 0.5 1.0 CB A:ASP378 3.7 67.5 1.0 NZ A:LYS238 3.7 75.5 1.0 CG A:ASP378 3.7 79.7 1.0 O A:HOH601 3.7 65.4 1.0 O3B A:ATP501 3.8 96.6 1.0 CE A:LYS238 4.0 69.8 1.0 PA A:ATP501 4.0 84.3 1.0 CB A:SER301 4.6 67.4 1.0 ND2 A:ASN236 4.6 72.1 1.0 C A:ASP299 4.7 0.5 1.0 O1A A:ATP501 4.7 84.3 1.0 N A:SER301 4.8 69.7 1.0 OD1 A:ASP378 4.9 78.6 1.0 O3A A:ATP501 4.9 83.9 1.0 PB A:ATP501 5.0 93.1 1.0 O1B A:ATP501 5.0 88.5 1.0 C5' A:ATP501 5.0 78.4 1.0

Calcium binding site 2 out of 2 in the Crystal Structure of Zebrafish Phosphatidylinositol-4-Phosphate 5- Kinase Alpha Isoform D236N with Bound Atp/CA2+


Mono view


Stereo pair view

A full contact list of Calcium with other atoms in the Ca binding site number 2 of Crystal Structure of Zebrafish Phosphatidylinositol-4-Phosphate 5- Kinase Alpha Isoform D236N with Bound Atp/CA2+ within 5.0Å range: probe atom residue distance (Å) B Occ A:Ca503 b:91.1 occ:1.00 O1B A:ATP501 2.6 88.5 1.0 OD1 A:ASP378 2.7 78.6 1.0 OD2 A:ASP378 2.7 74.9 1.0 O1G A:ATP501 3.1 0.2 1.0 CG A:ASP378 3.1 79.7 1.0 OE2 A:GLU177 3.7 78.8 1.0 PB A:ATP501 4.1 93.1 1.0 PG A:ATP501 4.4 0.5 1.0 O3B A:ATP501 4.6 96.6 1.0 CB A:ASP378 4.7 67.5 1.0 NZ A:LYS171 4.7 78.7 1.0 CD A:GLU177 4.7 80.4 1.0 O3A A:ATP501 5.0 83.9 1.0

X.Zeng, A.Uyar, D.Sui, N.Donyapour, D.Wu, A.Dickson, J.Hu. Structural Insights Into Lethal Contractural Syndrome Type 3 (LCCS3) Caused By A Missense Mutation of PIP5K Gamma. Biochem. J. V. 475 2257 2018.
ISSN: ESSN 1470-8728
PubMed: 29959184
DOI: 10.1042/BCJ20180326